A Cyclen-Based Tetraphosphinate Chelator for the Preparation of Radiolabeled Tetrameric Bioconjugates

Synthesis and Evaluation of Diastereoisomers of 1,4,7-Triazacyclononane-1,4,7-tris-(glutaric acid) (NOTGA) for Multimeric Radiopharmaceuticals of Gallium

(2012) Francisco L. Guerra Gomez et al.   BIOCONJUGATE CHEMISTRY

How is68Ga Labeling of Macrocyclic Chelators Influenced by Metal Ion Contaminants in68Ge/68Ga Generator Eluates?

(2012) Jakub Šimeček et al.   ChemMedChem

A Monoreactive Bifunctional Triazacyclononane Phosphinate Chelator with High Selectivity for Gallium-68

(2012) Jakub Šimeček et al.   ChemMedChem

Copper-64 labelling of triazacyclononane-triphosphinate chelators

(2012) Jakub Šimeček et al.   DALTON TRANSACTIONS

68Ga-NODAGA-RGD is a suitable substitute for 18F-Galacto-RGD and can be produced with high specific activity in a cGMP/GRP compliant automated process

(2012) Karolin Pohle et al.   NUCLEAR MEDICINE AND BIOLOGY

Be spoilt for choice with radiolabelled RGD peptides: Preclinical evaluation of 68Ga-TRAP(RGD)3

(2012) Johannes Notni et al.   NUCLEAR MEDICINE AND BIOLOGY

Synthesis and biological evaluation of RGD peptides with the99mTc/188Re chelated iminodiacetate core: highly enhanced uptake and excretion kinetics of theranostics against tumor angiogenesis

(2012) Byung Chul Lee et al.   RSC Advances

Bone-seeking TRAP conjugates: surprising observations and their implications on the development of gallium-68-labeled bisphosphonates

(2012) Johannes Notni et al.   EJNMMI Research

Comparative gallium-68 labeling of TRAP-, NOTA-, and DOTA-peptides: practical consequences for the future of gallium-68-PET

(2012) Johannes Notni et al.   EJNMMI Research

Increasing αvβ3 Selectivity of the Anti-Angiogenic Drug Cilengitide by N-Methylation

(2011) Carlos Mas-Moruno et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Cilengitide: The First Anti-Angiogenic Small Molecule Drug Candidate. Design, Synthesis and Clinical Evaluation

(2011) Carlos Mas-Moruno et al.   Anti-Cancer Agents in Medicinal Chemistry

Multivalent Bifunctional Chelator Scaffolds for Gallium-68 Based Positron Emission Tomography Imaging Probe Design: Signal Amplification via Multivalency

(2011) Ajay N. Singh et al.   BIOCONJUGATE CHEMISTRY

TRAP, a Powerful and Versatile Framework for Gallium-68 Radiopharmaceuticals

(2011) Johannes Notni et al.   CHEMISTRY-A EUROPEAN JOURNAL

Complexation of Metal Ions with TRAP (1,4,7-Triazacyclononane Phosphinic Acid) Ligands and 1,4,7-Triazacyclononane-1,4,7-triacetic Acid: Phosphinate-Containing Ligands as Unique Chelators for Trivalent Gallium

(2011) Jakub Šimeček et al.   INORGANIC CHEMISTRY

Multimerization of cRGD Peptides by Click Chemistry: Synthetic Strategies, Chemical Limitations, and Influence on Biological Properties

(2010) Carmen Wängler  et al.   CHEMBIOCHEM

A Triazacyclononane-Based Bifunctional Phosphinate Ligand for the Preparation of Multimeric68Ga Tracers for Positron Emission Tomography

(2010) Johannes Notni et al.   CHEMISTRY-A EUROPEAN JOURNAL

PET imaging of αvβ3 integrin expression in tumours with 68Ga-labelled mono-, di- and tetrameric RGD peptides

(2010) Ingrid Dijkgraaf et al.   EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING

Gallium(III) Complexes of DOTA and DOTA−Monoamide: Kinetic and Thermodynamic Studies

(2010) Vojtěch Kubíček et al.   INORGANIC CHEMISTRY

New chelators tailored for Ga(III) and radiolabelling with gallium-68

(2010) Jakub Šimeček et al.   NUCLEAR MEDICINE AND BIOLOGY

Multivalent cyclic RGD ligands: influence of linker lengths on receptor binding

(2010) Holger Kubas et al.   NUCLEAR MEDICINE AND BIOLOGY

Comparison of different phosphorus-containing ligands complexing68Ga for PET-imaging of bone metabolism

(2010) M. Fellner et al.   RADIOCHIMICA ACTA

Preclinical and Clinical Studies of Peptide Receptor Radionuclide Therapy

(2010) Stefan E. Pool et al.   SEMINARS IN NUCLEAR MEDICINE

Ligands for Mapping αvβ3-Integrin Expression in Vivo

(2009) Margret Schottelius et al.   ACCOUNTS OF CHEMICAL RESEARCH

Radiolabeled Cyclic RGD Peptides as Integrin αvβ3-Targeted Radiotracers: Maximizing Binding Affinity via Bivalency

(2009) Shuang Liu   BIOCONJUGATE CHEMISTRY

The coordination chemistry of 1,4,7,10-tetraazacyclododecane-N,N′,N″,N′″-tetraacetic acid (H4DOTA): Structural overview and analyses on structure–stability relationships

(2009) Nerissa Viola-Villegas et al.   COORDINATION CHEMISTRY REVIEWS

Peptide-receptor radionuclide therapy for endocrine tumors

(2009) Martijn van Essen et al.   Nature Reviews Endocrinology

Lanthanide Complexes of 2,2′,2″-(10-{[Hydroxy(phenyl)phosphoryl]methyl}-1,4,7,10-tetraazacyclododecan-1,4,7-triyl)triacetic Acid: Structural Characterisation of Intermediates from the Proposed Complexation Mechanism in the Systems of LnIII-dota-Type Ligands

(2008) Pavel Vojtíšek et al.   EUROPEAN JOURNAL OF INORGANIC CHEMISTRY

Lanthanide(III) Complexes of Phosphorus Acid Analogues of H4DOTA as Model Compounds for the Evaluation of the Second-Sphere Hydration

(2008) Zuzana Kotková et al.   EUROPEAN JOURNAL OF INORGANIC CHEMISTRY

68Ga-labeled multimeric RGD peptides for microPET imaging of integrin αvβ3 expression

(2008) Zi-Bo Li et al.   EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING

Syntheses, structures and catalytic properties of one-dimensional lanthanide-dotp compounds [dotpH8=1,4,7,10-tetraazacyclododecane-1,4,7,10-tetrakis-(methylenephosphonic acid)]

(2008) Ting-Hai Yang et al.   INORGANIC CHEMISTRY COMMUNICATIONS

Chemical and biological evaluation of 153Sm and 166Ho complexes of 1,4,7,10-tetraazacyclododecane-1,4,7,10-tetrakis(methylphosphonic acid monoethylester) (H4dotpOEt)

(2008) Michaela Försterová et al.   JOURNAL OF INORGANIC BIOCHEMISTRY