Increasing αvβ3 Selectivity of the Anti-Angiogenic Drug Cilengitide by N-Methylation

Cilengitide: The First Anti-Angiogenic Small Molecule Drug Candidate. Design, Synthesis and Clinical Evaluation

(2011) Carlos Mas-Moruno et al.   Anti-Cancer Agents in Medicinal Chemistry

The Impact of Amino Acid Side Chain Mutations in Conformational Design of Peptides and Proteins

(2010) Burkhardt Laufer et al.   CHEMISTRY-A EUROPEAN JOURNAL

MultipleN-Methylation of MT-II Backbone Amide Bonds Leads to Melanocortin Receptor Subtype hMC1R Selectivity: Pharmacological and Conformational Studies

(2010) Lucas Doedens et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Novel analogues of the therapeutic complement inhibitor compstatin with significantly improved affinity and potency

(2010) Hongchang Qu et al.   MOLECULAR IMMUNOLOGY

Integrins as therapeutic targets: lessons and opportunities

(2010) Dermot Cox et al.   NATURE REVIEWS DRUG DISCOVERY

Targeting integrins in malignant glioma

(2010) Ghazaleh Tabatabai et al.   Targeted Oncology

 v 3/ v 5 Integrins-FAK-RhoB: A Novel Pathway for Hypoxia Regulation in Glioblastoma

(2009) N. Skuli et al.   CANCER RESEARCH

Rapid Optimization of a Peptide Inhibitor of Malaria Parasite Invasion by ComprehensiveN-Methyl Scanning

(2009) Karen S. Harris et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Poly-N-methylated Amyloid β-Peptide (Aβ) C-Terminal Fragments Reduce Aβ Toxicity in Vitro and inDrosophila melanogaster

(2009) Partha Pratim Bose et al.   JOURNAL OF MEDICINAL CHEMISTRY

Will integrin inhibitors have proangiogenic effects in the clinic?

(2009) Michael Weller et al.   NATURE MEDICINE

Reply to: “Will integrin inhibitors have proangiogenic effects in the clinic?”

(2009) Andrew R Reynolds et al.   NATURE MEDICINE

Stimulation of tumor growth and angiogenesis by low concentrations of RGD-mimetic integrin inhibitors

(2009) Andrew R Reynolds et al.   NATURE MEDICINE

N-Methylation of Peptides: A New Perspective in Medicinal Chemistry

(2008) Jayanta Chatterjee et al.   ACCOUNTS OF CHEMICAL RESEARCH

Conformational Preference and Potential Templates ofN-Methylated Cyclic Pentaalanine Peptides

(2007) Jayanta Chatterjee et al.   CHEMISTRY-A EUROPEAN JOURNAL