☆ 4.3 Article

Direct Synthesis of Acyl Azides from Carboxylic Acids Using 2-Azido-1,3-dimethylimidazolinium Chloride

CHEMISTRY LETTERS (2010)

Journal

CHEMISTRY LETTERS

Volume 39, Issue 7, Pages 732-733

Publisher

CHEMICAL SOC JAPAN

DOI: 10.1246/cl.2010.732

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Chemistry, Multidisciplinary

Funding

Ministry of Education, Culture, Sports, Science and Technology

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Abstract

Acyl azides were directly synthesized from carboxylic acids by the treatment with 2-azido-1,3-dimethylimidazolinium chloride (ADMC, 1) and amine. This procedure resulted in acyl azides in good yields and was applied to the amidation of amino acid derivatives without racemization of the products.

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