Journal
CHEMISTRY & BIODIVERSITY
Volume 10, Issue 10, Pages 1903-1908Publisher
WILEY-V C H VERLAG GMBH
DOI: 10.1002/cbdv.201300072
Keywords
Pteris ensiformis; Sesquiterpenes; Pterosin sesquiterpenes; Antitubercular activity
Funding
- National Science Council of the Republic of China [NSC 95-2320-B-127-001-MY3, NSC 98-2320-B-127-001-MY3, NSC 101-2320-B-127-001-MY3]
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Two new pterosin sesquiterpenes, (2S)-13-hydroxypterosin A (1) and (2S,3S)-12-hydroxypterosin Q (2), were isolated from the whole plants of Pteris ensiformis, together with six known compounds. The structures of 1 and 2 were determined through extensive 1D/2D-NMR and MS analyses. Compound 2 exhibited antitubercular activity (MIC 6.25g/ml) against Mycobacterium tuberculosis H(37)Rv in vitro.
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