Journal
CHEMISTRY & BIODIVERSITY
Volume 10, Issue 8, Pages 1494-1500Publisher
WILEY-V C H VERLAG GMBH
DOI: 10.1002/cbdv.201200213
Keywords
Hyptis suaveolens; Abietanes; Diterpenes; Antimycobacterial activity; Cytotoxic activity
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Investigation of the constituents of the whole plant of Hyptis suaveolens led to the isolation of three new abietane diterpenes, isosuaveolic acid (1), 8,9-epoxysuaveolic acid (2), and 14-O-methylsuaveolic acid (3), together with eleven known compounds. The structures of 1-3 were established by spectroscopic methods and chemical correlations. Some isolates were tested for their antimycobacterial and cytotoxic activities.
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