Catalytic activations of unstrained C–C bond involving organometallic intermediates

Directed Decarbonylation of Unstrained Aryl Ketones via Nickel-Catalyzed C—C Bond Cleavage

(2018) Tian-Tian Zhao et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Direct Alkenylation of Allylbenzenes via Chelation-Assisted C–C Bond Cleavage

(2018) Shunsuke Onodera et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Suzuki–Miyaura Coupling of Simple Ketones via Activation of Unstrained Carbon–Carbon Bonds

(2018) Ying Xia et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Nickel-Mediated Decarbonylation of Simple Unstrained Ketones through the Cleavage of Carbon–Carbon Bonds

(2017) Toshifumi Morioka et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Rhodium-Catalyzed Homocoupling of γ-Alkylated tert-Propargylic Alcohols

(2017) Xiaowei Dou et al.   ORGANIC LETTERS

Rhodium-Catalyzed Asymmetric Conjugate Alkynylation of β,γ-Unsaturated α-Ketoesters

(2017) Yanle Zhi et al.   ORGANIC LETTERS

Oxidative coupling of sp 2 and sp 3 carbon–hydrogen bonds to construct dihydrobenzofurans

(2017) Jiang-Ling Shi et al.   Nature Communications

“Cut and Sew” Transformations via Transition-Metal-Catalyzed Carbon–Carbon Bond Activation

(2017) Peng-hao Chen et al.   ACS Catalysis

Lanthanide-Catalyzed Reversible Alkynyl Exchange by Carbon-Carbon Single-Bond Cleavage Assisted by a Secondary Amino Group

(2016) Yinlin Shao et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

A Simple and Versatile Amide Directing Group for C−H Functionalizations

(2016) Ru-Yi Zhu et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Synthesis and applications of rhodacyclopentanones derived from C–C bond activation

(2016) Megan H. Shaw et al.   CHEMICAL COMMUNICATIONS

Potential of Metal-Catalyzed C–C Single Bond Cleavage for Organic Synthesis

(2016) Masahiro Murakami et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Catalytic activation of carbon–carbon bonds in cyclopentanones

(2016) Ying Xia et al.   NATURE

Remote C−H alkylation and C−C bond cleavage enabled by an in situ generated palladacycle

(2016) Juntao Ye et al.   Nature Chemistry

Rhodium-Catalyzed Interconversion of Quinolinyl Ketones with Boronic Acids via C–C Bond Activation

(2016) Joseph M. Dennis et al.   ORGANIC LETTERS

Efficient Benzimidazolidinone Synthesis via Rhodium-Catalyzed Double-Decarbonylative C–C Activation/Cycloaddition between Isatins and Isocyanates

(2016) Rong Zeng et al.   ACS Catalysis

Rhodium-Catalyzed [5 + 2 + 1] Cycloaddition of Ene–Vinylcyclopropanes and CO: Reaction Design, Development, Application in Natural Product Synthesis, and Inspiration for Developing New Reactions for Synthesis of Eight-Membered Carbocycles

(2015) Yi Wang et al.   ACCOUNTS OF CHEMICAL RESEARCH

Asymmetric Conjugate Alkynylation of Cyclic α,β-Unsaturated Carbonyl Compounds with a Chiral Diene Rhodium Catalyst

(2015) Xiaowei Dou et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Synthesis of Enantioenriched 5,6-Dihydrophenanthridine Derivatives through retro-Carbopalladation of Chiralo-Bromobenzylamines

(2015) Juntao Ye et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Rh/Cu-catalyzed multiple C–H, C–C, and C–N bond cleavage: facile synthesis of pyrido[2,1-a]indoles from 1-(pyridin-2-yl)-1H-indoles and γ-substituted propargyl alcohols

(2015) Ting Li et al.   CHEMICAL COMMUNICATIONS

Catalytic C–C Bond Activations via Oxidative Addition to Transition Metals

(2015) Laetitia Souillart et al.   CHEMICAL REVIEWS

Transition metal-catalyzed ketone-directed or mediated C–H functionalization

(2015) Zhongxing Huang et al.   CHEMICAL SOCIETY REVIEWS

C–C Activation by Retro-Aldol Reaction of Two β-Hydroxy Carbonyl Compounds: Synergy with Pd-Catalyzed Cross-Coupling To Access Mono-α-arylated Ketones and Esters

(2015) Song-Lin Zhang et al.   JOURNAL OF ORGANIC CHEMISTRY

Synthesis of Multisubstituted Triphenylenes and Phenanthrenes by Cascade Reaction of o-Iodobiphenyls or (Z)-β-Halostyrenes with o-Bromobenzyl Alcohols through Two Sequential C–C Bond Formations Catalyzed by a Palladium Complex

(2015) Masayuki Iwasaki et al.   JOURNAL OF ORGANIC CHEMISTRY

Group Exchange between Ketones and Carboxylic Acids through Directing Group Assisted Rh-Catalyzed Reorganization of Carbon Skeletons

(2015) Zhi-Quan Lei et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Rh-Catalyzed Decarbonylative Coupling with Alkynes via C–C Activation of Isatins

(2015) Rong Zeng et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Controlled Rh-Catalyzed Mono- and Double-decarbonylation of Alkynyl α-Diones To Form Conjugated Ynones and Disubstituted Alkynes

(2015) Rachel E. Whittaker et al.   ORGANIC LETTERS

Csp3–Csp3 Bond Cleavage in the Palladium-Catalyzed Aminohydroxylation of Allylic Hydrazones Using Atmospheric Oxygen as the Sole Oxidant

(2015) Yu-Chen Chen et al.   ORGANIC LETTERS

Palladium-Catalyzed Allylic Amination of Homoallylic Alcohols with Amines via Carbon–Carbon Bond Cleavage

(2015) Qiang Kang et al.   SYNTHESIS-STUTTGART

Rh-catalyzed decarbonylation of conjugated ynones via carbon–alkyne bond activation: reaction scope and mechanistic exploration via DFT calculations

(2015) Alpay Dermenci et al.   Chemical Science

Cobalt(III)-Catalyzed Functionalization of Unstrained Carbon–Carbon Bonds through β-Carbon Cleavage of Alcohols

(2015) Erhan Ozkal et al.   ACS Catalysis

Copper-catalyzed carbon–carbon bond cleavage of primary propargyl alcohols: β-carbon elimination of hemiaminal intermediates

(2015) Ye-Won Kang et al.   Catalysis Science & Technology

Selective Carbon-Carbon Bond Cleavage for the Stereoselective Synthesis of Acyclic Systems

(2014) Ilan Marek et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Recent Advances in Transition-Metal-Catalyzed Functionalization of Unstrained Carbon–Carbon Bonds

(2014) Feng Chen et al.   CHEMICAL REVIEWS

Unstrained CarbonCarbon Bond Cleavage

(2014) Hui Liu et al.   Chemistry-An Asian Journal

Substitution Controlled Functionalization of ortho-Bromobenzylic Alcohols via Palladium Catalysis: Synthesis of Chromenes and Indenols

(2014) Lodi Mahendar et al.   JOURNAL OF ORGANIC CHEMISTRY

Palladium-Catalyzed Allylic Esterification via C–C Bond Cleavage of a Secondary Homoallyl Alcohol

(2014) Yong Wang et al.   ORGANIC LETTERS

Direct activation of relatively unstrained carbon–carbon bonds in homogeneous systems

(2014) Alpay Dermenci et al.   Organic Chemistry Frontiers

Gold-Catalyzed Tandem Reactions of Methylenecyclopropanes and Vinylidenecyclopropanes

(2013) Di-Han Zhang et al.   ACCOUNTS OF CHEMICAL RESEARCH

The Cross-Dehydrogenative Coupling of C sp 3H Bonds: A Versatile Strategy for CC Bond Formations

(2013) Simon A. Girard et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Steric and Electronic Effects Influencing β-Aryl Elimination in the Pd-catalyzed Carbon–Carbon Single Bond Activation of Triarylmethanols

(2013) James R. Bour et al.   JOURNAL OF ORGANIC CHEMISTRY

Rh(I)-Catalyzed Decarbonylation of Diynones via C–C Activation: Orthogonal Synthesis of Conjugated Diynes

(2013) Alpay Dermenci et al.   ORGANIC LETTERS

Palladium-Catalyzed Annulation of o-Iodobiphenyls with o-Bromobenzyl Alcohols: Synthesis of Functionalized Triphenylenes via C–C and C–H Bond Cleavages

(2013) Masayuki Iwasaki et al.   ORGANIC LETTERS

Reductive Cleavage of the C sp 2C sp 3 Bond of Secondary Benzyl Alcohols: Rhodium Catalysis Directed by N-Containing Groups

(2012) Kang Chen et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Direct Exchange of a Ketone Methyl or Aryl Group to Another Aryl Group through CC Bond Activation Assisted by Rhodium Chelation

(2012) Jingjing Wang et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Extrusion of CO from Aryl Ketones: Rhodium(I)-Catalyzed CC Bond Cleavage Directed by a Pyridine Group

(2012) Zhi-Quan Lei et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Rh-Catalyzed CC Cleavage of Benzyl/Allylic Alcohols to Produce Benzyl/Allylic Amines or other Alcohols by Nucleophilic Addition of Intermediate Rhodacycles to Aldehydes and Imines

(2012) Xi-Sha Zhang et al.   CHEMISTRY-A EUROPEAN JOURNAL

Pd-Catalyzed Sequential C–C Bond Formation and Cleavage: Evidence for an Unexpected Generation of Arylpalladium(II) Species

(2012) So Won Youn et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Rhodium-Catalyzed Acyl-Transfer Reaction between Benzyl Ketones and Thioesters: Synthesis of Unsymmetric Ketones by Ketone CO–C Bond Cleavage and Intermolecular Rearrangement

(2012) Mieko Arisawa et al.   ORGANIC LETTERS

A Domino Palladium-Catalyzed C–C and C–O Bonds Formation via Dual O–H Bond Activation: Synthesis of 6,6-Dialkyl-6H-benzo[c]chromenes

(2012) Lodi Mahendar et al.   ORGANIC LETTERS

Direct oxidative arylation via rhodium-catalyzed C–C bond cleavage of secondary alcohols with arylsilanes

(2012) Kang Chen et al.   Chemical Science

Weak Coordination as a Powerful Means for Developing Broadly Useful C–H Functionalization Reactions

(2011) Keary M. Engle et al.   ACCOUNTS OF CHEMICAL RESEARCH

Allyl-, Allenyl-, and Propargyl-Transfer Reactions through Cleavage of CC Bonds Catalyzed by an N-Heterocyclic Carbene/Copper Complex: Synthesis of Multisubstituted Pyrroles

(2011) Masahiro Sai et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Strained small rings in gold-catalyzed rapid chemical transformations

(2011) Bei-Li Lu et al.   CHEMICAL SOCIETY REVIEWS

Copper(I)-Catalyzed Deacetylenative Coupling of Propargylic Amines: An Efficient Synthesis of Symmetric 1,4-Diamino-2-butynes

(2011) Yongeun Kim et al.   CHEMISTRY-A EUROPEAN JOURNAL

Cleavage of unreactive bonds with pincer metal complexes

(2011) Martin Albrecht et al.   DALTON TRANSACTIONS

Rhodium-Catalyzed Acylation with Quinolinyl Ketones: Carbon−Carbon Single Bond Activation as the Turnover-Limiting Step of Catalysis

(2011) Colin M. Rathbun et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Rate-Limiting Step of the Rh-Catalyzed Carboacylation of Alkenes: C–C Bond Activation or Migratory Insertion?

(2011) J. Patrick Lutz et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Pyridinyl Directed Alkenylation with Olefins via Rh(III)-Catalyzed C–C Bond Cleavage of Secondary Arylmethanols

(2011) Hu Li et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Palladium-Catalyzed Arylative Ring-Opening Reactions of Norbornenols: Entry to Highly Substituted Cyclohexenes, Quinolines, and Tetrahydroquinolines

(2010) Michael Waibel et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Desymmetrizations of meso-tert-norbornenols by rhodium(i)-catalyzed enantioselective retro-allylations

(2010) Michael Waibel et al.   CHEMICAL COMMUNICATIONS

Metal-catalysed cleavage of carbon–carbon bonds

(2010) Masahiro Murakami et al.   CHEMICAL COMMUNICATIONS

Overview of the Mechanistic Work on the Concerted Metallation–Deprotonation Pathway

(2010) David Lapointe et al.   CHEMISTRY LETTERS

Palladium-Catalyzed Allylation of Aryl Halides with Homoallyl Alcohols Bearing a Trisubstituted Double Bond: Application to Chirality Transfer from Hydroxylated Carbon to Benzylic One

(2010) Ryota Wakabayashi et al.   JOURNAL OF ORGANIC CHEMISTRY

Metalloradical-Catalyzed Aliphatic Carbon−Carbon Activation of Cyclooctane

(2010) Yun Wai Chan et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Copper(I)-Catalyzed Substitution Reactions of Propargylic Amines: Importance of C(sp)−C(sp3) Bond Cleavage in Generation of Iminium Intermediates

(2010) Tsuyuka Sugiishi et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Nickel-Catalyzed Arylative Ring-Opening of 3-Methylenecycloalkane-1,1-dicarboxylates

(2010) Yuto Sumida et al.   ORGANIC LETTERS

Rhodium-catalyzed oxidative alkynylation of acrylate esters with propargylic alcohols

(2010) Takahiro Nishimura et al.   TETRAHEDRON LETTERS

Chemoselectivity in Catalytic CC and CH Bond Activation: Controlling Intermolecular Carboacylation and Hydroarylation of Alkenes

(2009) Michael T. Wentzel et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Cross Dehydrogenative Arylation (CDA) of a Benzylic CH Bond with Arenes by Iron Catalysis

(2009) Yi-Zhou Li et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Palladium-Catalyzed 1-Methylene-2-propenylation Reactions of Aryl Bromides with 3,4-Alkadien-1-ols via Carbon–Carbon Bond Cleavage for the Synthesis of 2-Aryl-1,3-butadiene Derivatives

(2009) Junichi Imoto et al.   BULLETIN OF THE CHEMICAL SOCIETY OF JAPAN

A heterogeneous Ru/CeO2 catalyst effective for transfer-allylation from homoallyl alcohols to aldehydes

(2009) Hiroki Miura et al.   CHEMICAL COMMUNICATIONS

Palladium-Catalyzed (N-Oxido-2-pyridinyl)methyl Transfer from 2-(2-Hydroxyalkyl)pyridineN-Oxide to Aryl Halides by β-Carbon Elimination

(2009) Takafumi Suehiro et al.   Chemistry-An Asian Journal

A Pd(II)-Catalyzed Ring-Expansion Reaction of Cyclic 2-Azidoalcohol Derivatives: Synthesis of Azaheterocycles

(2009) Shunsuke Chiba et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Cross-Dehydrogenative Coupling (CDC): Exploring C−C Bond Formations beyond Functional Group Transformations

(2008) Chao-Jun Li   ACCOUNTS OF CHEMICAL RESEARCH

Rhodium-Catalyzed Rearrangement of Aryl Bis(alkynyl) Carbinols to 3-Alkynyl-1-indanones

(2008) Ryo Shintani et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Synthesis of Arylallenes by Palladium-Catalyzed Retro-Propargylation of Homopropargyl Alcohols

(2008) Sayuri Hayashi et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Catalytic Carbon−Carbon σ Bond Activation: An Intramolecular Carbo-Acylation Reaction with Acylquinolines

(2008) Ashley M. Dreis et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Nickel-Catalyzed Allylation of Allyl Carbonates with Homoallyl Alcohols via Retro-Allylation Providing 1,5-Hexadienes

(2008) Yuto Sumida et al.   ORGANIC LETTERS

Rhodium-Catalyzed Kinetic Resolution of Tertiary Homoallyl Alcohols via Stereoselective Carbon−Carbon Bond Cleavage

(2008) Ryo Shintani et al.   ORGANIC LETTERS

Generation of rhodium enolates via retro-aldol reaction and its application to regioselective aldol reaction

(2008) Kei Murakami et al.   TETRAHEDRON LETTERS

Multiple CH Activations To Construct Biologically Active Molecules in a Process Completely Free of Organohalogen and Organometallic Components

(2007) Bi-Jie Li et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Rhodium-Catalyzed Allylation of Aldehydes with Homoallylic Alcohols by Retroallylation and Isomerization to Saturated Ketones with Conventional or Microwave Heating

(2007) Yuto Sumida et al.   Chemistry-An Asian Journal

Rhodium-Catalyzed Oxidative Coupling of Triarylmethanols with Internal Alkynes via Successive C−H and C−C Bond Cleavages

(2007) Toshihiko Uto et al.   JOURNAL OF ORGANIC CHEMISTRY