Nanomaterials design and tests for neural tissue engineering

FGF-1 and proteolytically mediated cleavage site presentation influence three-dimensional fibroblast invasion in biomimetic PEGDA hydrogels

(2012) Sonja Sokic et al.   Acta Biomaterialia

Multifunctional Materials through Modular Protein Engineering

(2012) Rebecca L. DiMarco et al.   ADVANCED MATERIALS

The effect of oxidation on the degradation of photocrosslinkable alginate hydrogels

(2012) Oju Jeon et al.   BIOMATERIALS

Post-Self-Assembly Cross-Linking of Molecular Nanofibers for Oscillatory Hydrogels

(2012) Ye Zhang et al.   LANGMUIR

Injectable Solid Peptide Hydrogel as a Cell Carrier: Effects of Shear Flow on Hydrogels and Cell Payload

(2012) Congqi Yan et al.   LANGMUIR

Langevin Dynamics Simulation of Chain Crosslinking into Polymer Networks

(2012) Rongliang Wu et al.   MACROMOLECULAR THEORY AND SIMULATIONS

New bioactive motifs and their use in functionalized self-assembling peptides for NSC differentiation and neural tissue engineering

(2012) F. Gelain et al.   Nanoscale

BMHP1-Derived Self-Assembling Peptides: Hierarchically Assembled Structures with Self-Healing Propensity and Potential for Tissue Engineering Applications

(2011) Fabrizio Gelain et al.   ACS Nano

Hyaluronic Acid Hydrogels for Biomedical Applications

(2011) Jason A. Burdick et al.   ADVANCED MATERIALS

Zinc-Triggered Hydrogelation of a Self-Assembling β-Hairpin Peptide

(2011) Christopher M. Micklitsch et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Toward a Molecular Theory of Early and Late Events in Monomer to Amyloid Fibril Formation

(2011) John E. Straub et al.   Annual Review of Physical Chemistry

Solid-State NMR Studies of Amyloid Fibril Structure

(2011) Robert Tycko   Annual Review of Physical Chemistry

Solid-State NMR Characterization of Autofluorescent Fibrils Formed by the Elastin-Derived Peptide GVGVAGVG

(2011) Simon Sharpe et al.   BIOMACROMOLECULES

A novel strategy for preparing mechanically robust ionically cross-linked alginate hydrogels

(2011) Aparna Jejurikar et al.   Biomedical Materials

Viscoelastic properties and nanoscale structures of composite oligopeptide-polysaccharide hydrogels

(2011) Laura L. Hyland et al.   BIOPOLYMERS

Diffusion of small molecules inside a peptide hydrogel

(2011) Yue Feng et al.   CHEMICAL COMMUNICATIONS

DNA in a modern world

(2011) Eugen Stulz et al.   CHEMICAL SOCIETY REVIEWS

Modeling and simulation of pH-sensitive hydrogels

(2011) Thomas Wallmersperger et al.   COLLOID AND POLYMER SCIENCE

Preparation and characterization of composite nanofibers of polycaprolactone and nanohydroxyapatite for osteogenic differentiation of mesenchymal stem cells

(2011) Jyh-Ping Chen et al.   COLLOIDS AND SURFACES B-BIOINTERFACES

Tracking adult stem cells

(2011) Hugo J Snippert et al.   EMBO REPORTS

Computer simulations of the growth of synthetic peptide fibres

(2011) T. P. Stedall et al.   EUROPEAN PHYSICAL JOURNAL E

3D culture of adult mouse neural stem cells within functionalized self-assembling peptide scaffolds

(2011) Cunha et al.   International Journal of Nanomedicine

Structural Insights into Charge Pair Interactions in Triple Helical Collagen-like Proteins

(2011) Jorge A. Fallas et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Identification of targeting peptides for ischemic myocardium by in vivo phage display

(2011) Sachiko Kanki et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Enhanced Mechanical Rigidity of Hydrogels Formed from Enantiomeric Peptide Assemblies

(2011) Katelyn J. Nagy et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Effect of Glycine Substitution on Fmoc–Diphenylalanine Self-Assembly and Gelation Properties

(2011) Claire Tang et al.   LANGMUIR

Hydrogels in Poor Solvents: A Molecular Dynamics Study

(2011) Bernward A. F. Mann et al.   MACROMOLECULAR THEORY AND SIMULATIONS

Polyelectrolytes in Salt Solutions: Molecular Dynamics Simulations

(2011) Jan-Michael Y. Carrillo et al.   MACROMOLECULES

The use of the PeakForceTMquantitative nanomechanical mapping AFM-based method for high-resolution Young's modulus measurement of polymers

(2011) T J Young et al.   MEASUREMENT SCIENCE and TECHNOLOGY

Hierarchical Structure and Nanomechanics of Collagen Microfibrils from the Atomistic Scale Up

(2011) Alfonso Gautieri et al.   NANO LETTERS

Multi-hierarchical self-assembly of a collagen mimetic peptide from triple helix to nanofibre and hydrogel

(2011) Lesley E. R. O'Leary et al.   Nature Chemistry

Turning straw into gold: directing cell fate for regenerative medicine

(2011) Dena E. Cohen et al.   NATURE REVIEWS GENETICS

The self-assembly mechanism of fibril-forming silk-based block copolymers

(2011) Marieke Schor et al.   PHYSICAL CHEMISTRY CHEMICAL PHYSICS

Synthesis and dissipative particle dynamics simulation of cross-linkable fluorinated diblock copolymers: self-assembly aggregation behavior in different solvents

(2011) Shu-le Lin et al.   PHYSICAL CHEMISTRY CHEMICAL PHYSICS

Evaluation of Early and Late Effects into the Acute Spinal Cord Injury of an Injectable Functionalized Self-Assembling Scaffold

(2011) Daniela Cigognini et al.   PLoS One

In vivo imaging reveals a phase-specific role of STAT3 during central and peripheral nervous system axon regeneration

(2011) F. M. Bareyre et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Effects of chain length on oligopeptide hydrogelation

(2011) Marc B. Taraban et al.   Soft Matter

Molecular theory of weak polyelectrolyte thin films

(2011) Gabriel S. Longo et al.   Soft Matter

A Multiscale Approach to Characterize the Early Aggregation Steps of the Amyloid-Forming Peptide GNNQQNY from the Yeast Prion Sup-35

(2011) Jessica Nasica-Labouze et al.   PLoS Computational Biology

Polymer and Water Dynamics in Poly(vinyl alcohol)/Poly(methacrylate) Networks. A Molecular Dynamics Simulation and Incoherent Neutron Scattering Investigation

(2011) Gaio Paradossi et al.   Polymers

Transplantation of Nanostructured Composite Scaffolds Results in the Regeneration of Chronically Injured Spinal Cords

(2010) Fabrizio Gelain et al.   ACS Nano

Imaging of Self-Assembled Structures: Interpretation of TEM and Cryo-TEM Images

(2010) Heiner Friedrich et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Atomistic model of the spider silk nanostructure

(2010) Sinan Keten et al.   APPLIED PHYSICS LETTERS

Conformational Flexibility of Chitosan: A Molecular Modeling Study

(2010) Søren Skovstrup et al.   BIOMACROMOLECULES

Enzymatic Cross-Linking of a Nanofibrous Peptide Hydrogel

(2010) Erica L. Bakota et al.   BIOMACROMOLECULES

Self-assembly of peptide amphiphiles: From molecules to nanostructures to biomaterials

(2010) Honggang Cui et al.   BIOPOLYMERS

Controlled Release of Neurotrophin-3 and Platelet-Derived Growth Factor from Fibrin Scaffolds Containing Neural Progenitor Cells Enhances Survival and Differentiation into Neurons in a Subacute Model of SCI

(2010) Philip J. Johnson et al.   CELL TRANSPLANTATION

Energy transfer in self-assembled dipeptide hydrogels

(2010) Lin Chen et al.   CHEMICAL COMMUNICATIONS

Enzymatic formation of a photoresponsive supramolecular hydrogel

(2010) Xinming Li et al.   CHEMICAL COMMUNICATIONS

Rheological properties of peptide-based hydrogels for biomedical and other applications

(2010) Congqi Yan et al.   CHEMICAL SOCIETY REVIEWS

Using small angle scattering (SAS) to structurally characterise peptide and protein self-assembled materials

(2010) Jean-Baptiste Guilbaud et al.   CHEMICAL SOCIETY REVIEWS

Spinal cord injury in vitro: modelling axon growth inhibition

(2010) Mohammad Abu-Rub et al.   DRUG DISCOVERY TODAY

Molecular dynamics and experimental study of conformation change of poly(N-isopropylacrylamide) hydrogels in water

(2010) Jonathan Walter et al.   FLUID PHASE EQUILIBRIA

The sensors and regulators of cell-matrix surveillance in anoikis resistance of tumors

(2010) Lokesh Dalasanur Nagaprashantha et al.   INTERNATIONAL JOURNAL OF CANCER

Biocompatibility of poly(ethylene glycol)-based hydrogels in the brain: An analysis of the glial response across space and time

(2010) K. B. Bjugstad et al.   JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A

Relationship between population of the fibril-prone conformation in the monomeric state and oligomer formation times of peptides: Insights from all-atom simulations

(2010) Hoang Bao Nam et al.   JOURNAL OF CHEMICAL PHYSICS

Low molecular weight oligomers of amyloid peptides display β-barrel conformations: A replica exchange molecular dynamics study in explicit solvent

(2010) Alfonso De Simone et al.   JOURNAL OF CHEMICAL PHYSICS

Chitosan produces potent neuroprotection and physiological recovery following traumatic spinal cord injury

(2010) Y. Cho et al.   JOURNAL OF EXPERIMENTAL BIOLOGY

Self-assembling peptide amphiphile promotes plasticity of serotonergic fibers following spinal cord injury

(2010) Vicki M. Tysseling et al.   JOURNAL OF NEUROSCIENCE RESEARCH

Toward Modeling Thermoresponsive Polymer Networks: A Molecular Dynamics Simulation Study ofN-Isopropyl Acrylamide Co-oligomers

(2010) Ester Chiessi et al.   JOURNAL OF PHYSICAL CHEMISTRY B

Can Peptide Folding Simulations Provide Predictive Information for Aggregation Propensity?

(2010) Edmund I. Lin et al.   JOURNAL OF PHYSICAL CHEMISTRY B

Self-Assembling Multidomain Peptide Hydrogels: Designed Susceptibility to Enzymatic Cleavage Allows Enhanced Cell Migration and Spreading

(2010) Kerstin M. Galler et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Novel Anisotropic Supramolecular Hydrogel with High Stability over a Wide pH Range†

(2010) Fan Zhao et al.   LANGMUIR

Yielding Behavior in Injectable Hydrogels from Telechelic Proteins

(2010) Bradley D. Olsen et al.   MACROMOLECULES

Molecular Theory of Weak Polyelectrolyte Gels: The Role of pH and Salt Concentration

(2010) Gabriel S. Longo et al.   MACROMOLECULES

Molecular and Nanostructural Mechanisms of Deformation, Strength and Toughness of Spider Silk Fibrils

(2010) Andrea Nova et al.   NANO LETTERS

A self-assembly pathway to aligned monodomain gels

(2010) Shuming Zhang et al.   NATURE MATERIALS

Transplantation of human bone marrow stromal cell-derived Schwann cells reduces cystic cavity and promotes functional recovery after contusion injury of adult rat spinal cord

(2010) Takahito Kamada et al.   NEUROPATHOLOGY

The neuroprotective effects of fibronectin mats and fibronectin peptides following spinal cord injury in the rat

(2010) V.R. King et al.   NEUROSCIENCE

Identification of a Cardiac Specific Protein Transduction Domain by In Vivo Biopanning Using a M13 Phage Peptide Display Library in Mice

(2010) Maliha Zahid et al.   PLoS One

Cryogenic Transmission Electron Microscopy for Direct Observation of Polymer and Small-Molecule Materials and Structures in Solution

(2010) Sheng Zhong et al.   Polymer Reviews

An outlook on organization of lipids in membranes: Searching for a realistic connection with the organization of biological membranes

(2010) Luis A. Bagatolli et al.   PROGRESS IN LIPID RESEARCH

Construction of tissue engineered nerve grafts and their application in peripheral nerve regeneration

(2010) Xiaosong Gu et al.   PROGRESS IN NEUROBIOLOGY

Extending the PRIME model for protein aggregation to all 20 amino acids

(2010) Mookyung Cheon et al.   PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS

Injectable solid hydrogel: mechanism of shear-thinning and immediate recovery of injectable β-hairpin peptide hydrogels

(2010) Congqi Yan et al.   Soft Matter

Atomic force microscopy of biological samples

(2010) David P. Allison et al.   Wiley Interdisciplinary Reviews-Nanomedicine and Nanobiotechnology

Electrospinning of polysaccharides for regenerative medicine

(2009) Kuen Yong Lee et al.   ADVANCED DRUG DELIVERY REVIEWS

Revealing the Design Principles of High-Performance Biological Composites Using Ab initio and Multiscale Simulations: The Example of Lobster Cuticle

(2009) Svetoslav Nikolov et al.   ADVANCED MATERIALS

A Constitutive Model of Soft Tissue: From Nanoscale Collagen to Tissue Continuum

(2009) Huang Tang et al.   ANNALS OF BIOMEDICAL ENGINEERING

Self-Assembly of Multidomain Peptides: Sequence Variation Allows Control over Cross-Linking and Viscoelasticity

(2009) Lorenzo Aulisa et al.   BIOMACROMOLECULES

Self-Assembled Fmoc-Peptides as a Platform for the Formation of Nanostructures and Hydrogels

(2009) Ron Orbach et al.   BIOMACROMOLECULES

Molecular dynamics simulation study of P (VP-co-HEMA) hydrogels: Effect of water content on equilibrium structures and mechanical properties

(2009) Seung G. Lee et al.   BIOMATERIALS

What Determines the Structure and Stability of KFFE Monomers, Dimers, and Protofibrils?

(2009) Giovanni Bellesia et al.   BIOPHYSICAL JOURNAL

Hydrogels as extracellular matrix mimics for 3D cell culture

(2009) Mark W. Tibbitt et al.   BIOTECHNOLOGY AND BIOENGINEERING

Delayed transplantation of human marrow stromal cell-seeded scaffolds increases transcallosal neural fiber length, angiogenesis, and hippocampal neuronal survival and improves functional outcome after traumatic brain injury in rats

(2009) Ye Xiong et al.   BRAIN RESEARCH

Integrins

(2009) Malgorzata Barczyk et al.   CELL AND TISSUE RESEARCH

Current applications and future perspectives of artificial nerve conduits

(2009) Xu Jiang et al.   EXPERIMENTAL NEUROLOGY

Atomistic simulation of nanomechanical properties of Alzheimer’s Aβ(1–40) amyloid fibrils under compressive and tensile loading

(2009) Raffaella Paparcone et al.   JOURNAL OF BIOMECHANICS

Fibrin-based tissue engineering scaffolds enhance neural fiber sprouting and delay the accumulation of reactive astrocytes at the lesion in a subacute model of spinal cord injury

(2009) Philip J. Johnson et al.   JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A

Effect of β-sheet propensity on peptide aggregation

(2009) Giovanni Bellesia et al.   JOURNAL OF CHEMICAL PHYSICS

Simulations of nucleation and elongation of amyloid fibrils

(2009) Jianing Zhang et al.   JOURNAL OF CHEMICAL PHYSICS

A simple route to interpenetrating network hydrogel with high mechanical strength

(2009) Qunwei Tang et al.   JOURNAL OF COLLOID AND INTERFACE SCIENCE

Microscopic Factors that Control β-Sheet Registry in Amyloid Fibrils Formed by Fragment 11–25 of Amyloid β Peptide: Insights from Computer Simulations

(2009) Lacramioara Negureanu et al.   JOURNAL OF MOLECULAR BIOLOGY

Effect of biodegradable fibrin scaffold on survival, migration, and differentiation of transplanted bone marrow stromal cells after cortical injury in rats

(2009) Hiroshi Yasuda et al.   JOURNAL OF NEUROSURGERY

Biomaterial Design Strategies for the Treatment of Spinal Cord Injuries

(2009) Karin S. Straley et al.   JOURNAL OF NEUROTRAUMA

Amyloid β-Protein: Experiment and Theory on the 21−30 Fragment

(2009) Megan M. Murray et al.   JOURNAL OF PHYSICAL CHEMISTRY B

A Coarse-Grained Model for Polyethylene Oxide and Polyethylene Glycol: Conformation and Hydrodynamics

(2009) Hwankyu Lee et al.   JOURNAL OF PHYSICAL CHEMISTRY B

Enzyme-Instructed Molecular Self-assembly Confers Nanofibers and a Supramolecular Hydrogel of Taxol Derivative

(2009) Yuan Gao et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Genetically Engineered Nanofiber-Like Viruses For Tissue Regenerating Materials

(2009) Anna Merzlyak et al.   NANO LETTERS

Self-assembling peptide nanofiber scaffold promotes the reconstruction of acutely injured brain

(2009) Jiasong Guo et al.   Nanomedicine-Nanotechnology Biology and Medicine

Electrospun nanofibers for neural tissue engineering

(2009) Jingwei Xie et al.   Nanoscale

An expanding arsenal of experimental methods yields an explosion of insights into protein folding mechanisms

(2009) Alice I Bartlett et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Effects of human neural stem cell transplantation in canine spinal cord hemisection

(2009) Seung-Hoon Lee et al.   NEUROLOGICAL RESEARCH

Dynamics of locking of peptides onto growing amyloid fibrils

(2009) G. Reddy et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Discovery of a functional protein complex of netrin-4, laminin γ1 chain, and integrin α6β1 in mouse neural stem cells

(2009) Fernanda I. Staquicini et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Phage library-screening: A powerful approach for generation of targeting-agents specific for normal pancreatic islet-cells and islet-cell carcinoma in vivo

(2009) S. Ueberberg et al.   REGULATORY PEPTIDES

Advances in Progenitor Cell Therapy Using Scaffolding Constructs for Central Nervous System Injury

(2009) Peter A. Walker et al.   Stem Cell Reviews and Reports

Incorporation of a matrix metalloproteinase-sensitive substrate into self-assembling peptides – A model for biofunctional scaffolds

(2008) Ying Chau et al.   BIOMATERIALS

The role of aligned polymer fiber-based constructs in the bridging of long peripheral nerve gaps

(2008) Young-tae Kim et al.   BIOMATERIALS

Electrospinning: Applications in drug delivery and tissue engineering

(2008) Travis J. Sill et al.   BIOMATERIALS

Peptide Aggregation in Finite Systems

(2008) Gurpreet Singh et al.   BIOPHYSICAL JOURNAL

Substrate Modulus Directs Neural Stem Cell Behavior

(2008) Krishanu Saha et al.   BIOPHYSICAL JOURNAL

Electrospun micro- and nanofiber tubes for functional nervous regeneration in sciatic nerve transections

(2008) Silvia Panseri et al.   BMC BIOTECHNOLOGY

Chemical modifications of AFM tips for the study of molecular recognition events

(2008) Régis Barattin et al.   CHEMICAL COMMUNICATIONS

Theory and simulations of charged polymers: From solution properties to polymeric nanomaterials

(2008) A DOBRYNIN   CURRENT OPINION IN COLLOID & INTERFACE SCIENCE

Exploring energy landscapes of protein folding and aggregation

(2008) Normand Mousseau   Frontiers in Bioscience-Landmark

Effects of Schwann cell alignment along the oriented electrospun chitosan nanofibers on nerve regeneration

(2008) Wei Wang et al.   JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A

Probing the mechanisms of fibril formation using lattice models

(2008) Mai Suan Li et al.   JOURNAL OF CHEMICAL PHYSICS

Detection of apoptosis in a rat model of focal cerebral ischemia using a homing peptide selected from in vivo phage display

(2008) Hai-Yan Hong et al.   JOURNAL OF CONTROLLED RELEASE

Prediction of Aggregation-Prone Regions in Structured Proteins

(2008) Gian Gaetano Tartaglia et al.   JOURNAL OF MOLECULAR BIOLOGY

Self-Assembling Nanofibers Inhibit Glial Scar Formation and Promote Axon Elongation after Spinal Cord Injury

(2008) V. M. Tysseling-Mattiace et al.   JOURNAL OF NEUROSCIENCE

Brain cortex regeneration affected by scaffold architectures

(2008) Darice Y. Wong et al.   JOURNAL OF NEUROSURGERY

Molecular Simulation Study of Peptide Amphiphile Self-Assembly

(2008) Yuri S. Velichko et al.   JOURNAL OF PHYSICAL CHEMISTRY B

A Templating Approach for Monodisperse Self-Assembled Organic Nanostructures

(2008) Steve R. Bull et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Self-Assembly of Nanodonut Structure from a Cone-Shaped Designer Lipid-like Peptide Surfactant†

(2008) Ulung Khoe et al.   LANGMUIR

Direct Observation of Early-Time Hydrogelation in β-Hairpin Peptide Self-Assembly

(2008) Tuna Yucel et al.   MACROMOLECULES

Self-Templated Nucleation in Peptide and Protein Aggregation

(2008) Stefan Auer et al.   PHYSICAL REVIEW LETTERS

Monte Carlo simulation of two interpenetrating polymer networks: Structure, swelling, and mechanical properties

(2008) Samuel Edgecombe et al.   POLYMER

Spontaneous β-helical fold in prion protein: The case of PrP(82-146)

(2008) Gloria A.A. Saracino et al.   PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS

Thermodynamics and dynamics of amyloid peptide oligomerization are sequence dependent

(2008) Yan Lu et al.   PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS

Metadynamics: a method to simulate rare events and reconstruct the free energy in biophysics, chemistry and material science

(2008) Alessandro Laio et al.   REPORTS ON PROGRESS IN PHYSICS

Effect of functionalization on the self-assembling propensity of β-sheet forming peptides

(2008) Francesca Taraballi et al.   Soft Matter

A Generic Mechanism of Emergence of Amyloid Protofilaments from Disordered Oligomeric Aggregates

(2008) Stefan Auer et al.   PLoS Computational Biology

Enhanced nerve regeneration through a bilayered chitosan tube: The effect of introduction of glycine spacer into the CYIGSR sequence

(2007) Wei Wang et al.   JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A

Phase Diagram for Assembly of Biologically-Active Peptide Amphiphiles†

(2007) Stefan Tsonchev et al.   JOURNAL OF PHYSICAL CHEMISTRY B

Charge states rather than propensity for β-structure determine enhanced fibrillogenesis in wild-type Alzheimer's β-amyloid peptide compared to E22Q Dutch mutant

(2002) Francesca Massi et al.   PROTEIN SCIENCE