Out of fuzzy chemistry: from prebiotic chemistry to metabolic networks

Elements of Metabolic Evolution

(2012) Claudia Huber et al.   CHEMISTRY-A EUROPEAN JOURNAL

Exploratory Experiments on the Chemistry of the “Glyoxylate Scenario”: Formation of Ketosugars from Dihydroxyfumarate

(2012) Vasudeva Naidu Sagi et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Metabolic Networks of Sodalis glossinidius: A Systems Biology Approach to Reductive Evolution

(2012) Eugeni Belda et al.   PLoS One

Enzyme functional evolution through improved catalysis of ancestrally nonpreferred substrates

(2012) R. Huang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Etiology of Potentially Primordial Biomolecular Structures: From Vitamin B12 to the Nucleic Acids and an Inquiry into the Chemistry of Life’s Origin: A Retrospective

(2011) Albert Eschenmoser   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

The Moderately Efficient Enzyme: Evolutionary and Physicochemical Trends Shaping Enzyme Parameters

(2011) Arren Bar-Even et al.   BIOCHEMISTRY

Early evolution without a tree of life

(2011) William F Martin   Biology Direct

Toward a Systems Biology Perspective on Enzyme Evolution

(2011) Shelley D. Copley   JOURNAL OF BIOLOGICAL CHEMISTRY

Origins of Specificity and Promiscuity in Metabolic Networks

(2011) Pablo Carbonell et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Synthesis of Carbohydrates in Mineral-Guided Prebiotic Cycles

(2011) Hyo-Joong Kim et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

From L'Homme Machine to metabolic closure: Steps towards understanding life

(2011) Juan-Carlos Letelier et al.   JOURNAL OF THEORETICAL BIOLOGY

Computation of metabolic fluxes and efficiencies for biological carbon dioxide fixation

(2011) Nanette R. Boyle et al.   METABOLIC ENGINEERING

Microfossils of sulphur-metabolizing cells in 3.4-billion-year-old rocks of Western Australia

(2011) David Wacey et al.   Nature Geoscience

Prebiotic chemistry: a new modus operandi

(2011) M. W. Powner et al.   PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

An optimal degree of physical and chemical heterogeneity for the origin of life?

(2011) J. W. Szostak   PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

Physical limits of cells and proteomes

(2011) K. A. Dill et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The molecular origins of evolutionary innovations

(2011) Andreas Wagner   TRENDS IN GENETICS

Enzyme Promiscuity: A Mechanistic and Evolutionary Perspective

(2010) Olga Khersonsky and Dan S. Tawfik   Annual Review of Biochemistry

Alternative Pathways of Carbon Dioxide Fixation: Insights into the Early Evolution of Life?

(2010) Georg Fuchs   Annual Review of Microbiology

When metabolism meets topology: Reconciling metabolite and reaction networks

(2010) Raul Montañez et al.   BIOESSAYS

A New Replicator: A theoretical framework for analysing replication

(2010) István Zachar et al.   BMC BIOLOGY

The Structures and Physicochemical Properties of Organic Cofactors in Biocatalysis

(2010) Julia D. Fischer et al.   JOURNAL OF MOLECULAR BIOLOGY

Messy biology and the origins of evolutionary innovations

(2010) Dan S Tawfik   Nature Chemical Biology

Which Way to Life?

(2010) Antonio Lazcano   ORIGINS OF LIFE AND EVOLUTION OF BIOSPHERES

The Role of Natural Selection in the Origin of Life

(2010) Iris Fry   ORIGINS OF LIFE AND EVOLUTION OF BIOSPHERES

Lack of evolvability in self-sustaining autocatalytic networks constraints metabolism-first scenarios for the origin of life

(2010) V. Vasas et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Historical Development of Origins Research

(2010) A. Lazcano   Cold Spring Harbor Perspectives in Biology

Crawling Out of the RNA World

(2009) Thomas R. Cech   CELL

The powerful law of the power law and other myths in network biology

(2009) Gipsi Lima-Mendez et al.   Molecular BioSystems

Absolute metabolite concentrations and implied enzyme active site occupancy in Escherichia coli

(2009) Bryson D Bennett et al.   Nature Chemical Biology

Evolution of biomolecular networks — lessons from metabolic and protein interactions

(2009) Takuji Yamada et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Protein Dynamism and Evolvability

(2009) N. Tokuriki et al.   SCIENCE

Origin of Life on Earth

(2009) Alonso Ricardo et al.   SCIENTIFIC AMERICAN

Evolutionary Plasticity and Innovations in Complex Metabolic Reaction Networks

(2009) João F. Matias Rodrigues et al.   PLoS Computational Biology

An Examination of the Role of Autocatalytic Cycles in the Chemistry of Proposed Primordial Reactions

(2008) Donna G. Blackmond   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Acetogenesis and the Wood–Ljungdahl pathway of CO2 fixation

(2008) Stephen W. Ragsdale et al.   BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS

The Implausibility of Metabolic Cycles on the Prebiotic Earth

(2008) Leslie E Orgel   PLOS BIOLOGY

Computational identification of obligatorily autocatalytic replicators embedded in metabolic networks

(2008) Ádám Kun et al.   GENOME BIOLOGY

From prebiotic chemistry to cellular metabolism—The chemical evolution of metabolism before Darwinian natural selection

(2007) Enrique Meléndez-Hevia et al.   JOURNAL OF THEORETICAL BIOLOGY