Artificial DNA cutters for DNA manipulation and genome engineering

Artificial Restriction DNA Cutters to Promote Homologous Recombination in Human Cells

(2011) Hitoshi Katada et al.   CURRENT GENE THERAPY

Homing Endonucleases: From Microbial Genetic Invaders to Reagents for Targeted DNA Modification

(2011) Barry L. Stoddard   STRUCTURE

The Discovery of Zinc Fingers and Their Applications in Gene Regulation and Genome Manipulation

(2010) Aaron Klug   Annual Review of Biochemistry

Zinc Finger Nucleases as tools to understand and treat human diseases

(2010) David Davis et al.   BMC Medicine

Activation of DNA Carbon−Hydrogen Bonds by Metal Complexes

(2010) Marguerite Pitié et al.   CHEMICAL REVIEWS

Zinc-finger nucleases: new strategies to target the rat genome

(2010) Aron M. Geurts et al.   CLINICAL SCIENCE

Directed Evolution of an Enhanced and Highly Efficient FokI Cleavage Domain for Zinc Finger Nucleases

(2010) Jing Guo et al.   JOURNAL OF MOLECULAR BIOLOGY

Gene Correction by Homologous Recombination With Zinc Finger Nucleases in Primary Cells From a Mouse Model of a Generic Recessive Genetic Disease

(2010) Jon P Connelly et al.   MOLECULAR THERAPY

Genome editing with engineered zinc finger nucleases

(2010) Fyodor D. Urnov et al.   NATURE REVIEWS GENETICS

The I-CreI meganuclease and its engineered derivatives: applications from cell modification to gene therapy

(2010) S. Arnould et al.   PROTEIN ENGINEERING DESIGN & SELECTION

Homing endonucleases: from basics to therapeutic applications

(2009) Maria J. Marcaida et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Artificial Restriction DNA Cutters as New Tools for Gene Manipulation

(2009) Hitoshi Katada et al.   CHEMBIOCHEM

Site-selective scission of human genome by artificial restriction DNA cutter

(2009) Kenichiro Ito et al.   CHEMICAL COMMUNICATIONS

Homologous recombination in human cells using artificial restriction DNA cutter

(2009) Hitoshi Katada et al.   CHEMICAL COMMUNICATIONS

Oxidation of an Oligonucleotide-Bound CeIII/Multiphosphonate Complex for Site-Selective DNA Scission

(2009) Tuomas Lönnberg et al.   CHEMISTRY-A EUROPEAN JOURNAL

Targeted approaches for gene therapy and the emergence of engineered meganucleases

(2009) Roman Galetto et al.   EXPERT OPINION ON BIOLOGICAL THERAPY

Origin of High Fidelity in Target-Sequence Recognition by PNA−Ce(IV)/EDTA Combinations as Site-Selective DNA Cutters

(2009) Yoshitaka Miyajima et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

High-frequency modification of plant genes using engineered zinc-finger nucleases

(2009) Jeffrey A. Townsend et al.   NATURE

Precise genome modification in the crop species Zea mays using zinc-finger nucleases

(2009) Vipula K. Shukla et al.   NATURE

Efficient targeting of expressed and silent genes in human ESCs and iPSCs using zinc-finger nucleases

(2009) Dirk Hockemeyer et al.   NATURE BIOTECHNOLOGY

Generation of single-chain LAGLIDADG homing endonucleases from native homodimeric precursor proteins

(2009) Hui Li et al.   NUCLEIC ACIDS RESEARCH

Efficient targeting of a SCID gene by an engineered single-chain homing endonuclease

(2009) Sylvestre Grizot et al.   NUCLEIC ACIDS RESEARCH

Knockout Rats via Embryo Microinjection of Zinc-Finger Nucleases

(2009) Aron M. Geurts et al.   SCIENCE

Zinc-finger nucleases: a powerful tool for genetic engineering of animals

(2009) Séverine Rémy et al.   TRANSGENIC RESEARCH

Mechanism of Eukaryotic Homologous Recombination

(2008) Joseph San Filippo et al.   Annual Review of Biochemistry

Site-Selective Blocking of PCR by a Caged Nucleotide Leading to Direct Creation of Desired Sticky Ends in The Products

(2008) Keita Tanaka et al.   CHEMBIOCHEM

DNA hydrolytic cleavage catalyzed by synthetic multinuclear metallonucleases

(2008) Changlin Liu et al.   DALTON TRANSACTIONS

Zinc-finger Nucleases: The Next Generation Emerges

(2008) Toni Cathomen et al.   MOLECULAR THERAPY

Molecular basis of xeroderma pigmentosum group C DNA recognition by engineered meganucleases

(2008) Pilar Redondo et al.   NATURE

Targeted gene inactivation in zebrafish using engineered zinc-finger nucleases

(2008) Xiangdong Meng et al.   NATURE BIOTECHNOLOGY

Artificial restriction DNA cutter for site-selective scission of double-stranded DNA with tunable scission site and specificity

(2008) Makoto Komiyama et al.   Nature Protocols

Solid-phase synthesis of pseudo-complementary peptide nucleic acids

(2008) Makoto Komiyama et al.   Nature Protocols

Sequence-specific DNA cleavage mediated by bipyridine polyamide conjugates

(2008) Philippe Simon et al.   NUCLEIC ACIDS RESEARCH

Prompt site-selective DNA hydrolysis by Ce(iv)–EDTA using oligonucleotide multiphosphonate conjugates

(2008) Tuomas Lönnberg et al.   ORGANIC & BIOMOLECULAR CHEMISTRY