Efficient new constructs against triple negative breast cancer cells: synthesis and preliminary biological study of ferrocifen–SAHA hybrids and related species

Synthesis and characterization of new ferrocenyl compounds with different alkyl chain lengths and functional groups to target breast cancer cells

(2013) José de Jesús Cázares-Marinero et al.   JOURNAL OF ORGANOMETALLIC CHEMISTRY

Inhibition of triple-negative breast cancer models by combinations of antibodies to EGFR

(2013) D. A. Ferraro et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Radiosensitizing Potential of Epigenetic Anticancer Drugs

(2012) Harlinde De Schutter et al.   Anti-Cancer Agents in Medicinal Chemistry

Organometallic Compounds: An Opportunity for Chemical Biology?

(2012) Malay Patra et al.   CHEMBIOCHEM

Redox Regulation of p53, Redox Effectors Regulated by p53: A Subtle Balance

(2011) Agnès Maillet et al.   ANTIOXIDANTS & REDOX SIGNALING

Addition of a histone deacetylase inhibitor redirects tamoxifen-treated breast cancer cells into apoptosis, which is opposed by the induction of autophagy

(2011) Scott Thomas et al.   BREAST CANCER RESEARCH AND TREATMENT

A phase II study of the histone deacetylase inhibitor vorinostat combined with tamoxifen for the treatment of patients with hormone therapy-resistant breast cancer

(2011) P N Munster et al.   BRITISH JOURNAL OF CANCER

Identification of human triple-negative breast cancer subtypes and preclinical models for selection of targeted therapies

(2011) Brian D. Lehmann et al.   JOURNAL OF CLINICAL INVESTIGATION

Suberoylanilide hydroxamic acid, a potent histone deacetylase inhibitor; its X-ray crystal structure and solid state and solution studies of its Zn(II), Ni(II), Cu(II) and Fe(III) complexes

(2011) Darren M. Griffith et al.   JOURNAL OF INORGANIC BIOCHEMISTRY

Discovery of a Tetrahydroisoquinoline-Based Hydroxamic Acid Derivative (ZYJ-34c) as Histone Deacetylase Inhibitor with Potent Oral Antitumor Activities

(2011) Yingjie Zhang et al.   JOURNAL OF MEDICINAL CHEMISTRY

Oxime Amides as a Novel Zinc Binding Group in Histone Deacetylase Inhibitors: Synthesis, Biological Activity, and Computational Evaluation

(2011) Cinzia B. Botta et al.   JOURNAL OF MEDICINAL CHEMISTRY

Aminoferrocene-Based Prodrugs Activated by Reactive Oxygen Species

(2011) Helen Hagen et al.   JOURNAL OF MEDICINAL CHEMISTRY

Redox modulation of p53: Mechanisms and functional significance

(2011) Do-Hee Kim et al.   MOLECULAR CARCINOGENESIS

Advances in metal-induced oxidative stress and human disease

(2011) Klaudia Jomova et al.   TOXICOLOGY

Synthesis and Biological Evaluation of JAHAs: Ferrocene-Based Histone Deacetylase Inhibitors

(2011) John Spencer et al.   ACS Medicinal Chemistry Letters

Epigenetics: an Expanding New Piece of the Stroke Puzzle

(2011) William J. Pearce   Translational Stroke Research

The histone deacetylase inhibitor suberoylanilide hydroxamic acid induces growth inhibition and enhances taxol-induced cell death in breast cancer

(2010) Yi-kang Shi et al.   CANCER CHEMOTHERAPY AND PHARMACOLOGY

Potential anti-cancer activity of N-hydroxy-7-(2-naphthylthio) heptanomide (HNHA), a histone deacetylase inhibitor, against breast cancer both in vitro and in vivo

(2010) Ki Cheong Park et al.   CANCER SCIENCE

A ferrocenyl derivative of hydroxytamoxifen elicits an estrogen receptor-independent mechanism of action in breast cancer cell lines

(2010) Anne Vessières et al.   JOURNAL OF INORGANIC BIOCHEMISTRY

Biological and Biophysical Properties of the Histone Deacetylase Inhibitor Suberoylanilide Hydroxamic Acid Are Affected by the Presence of Short Alkyl Groups on the Phenyl Ring

(2010) Frédérik Oger et al.   JOURNAL OF MEDICINAL CHEMISTRY

Organometallic Anticancer Compounds

(2010) Gilles Gasser et al.   JOURNAL OF MEDICINAL CHEMISTRY

Synthesis and biological activity of ferrocenyl derivatives of the non-steroidal antiandrogens flutamide and bicalutamide

(2010) Olivier Payen et al.   JOURNAL OF ORGANOMETALLIC CHEMISTRY

Facile synthesis and strong antiproliferative activity of disubstituted diphenylmethylidenyl-[3]ferrocenophanes on breast and prostate cancer cell lines

(2010) Meral Görmen et al.   MedChemComm

Targeting proteins with metal complexes

(2009) Eric Meggers   CHEMICAL COMMUNICATIONS

A novel anti-cancer bifunctional platinum drug candidate with dual DNA binding and histone deacetylase inhibitory activity

(2009) Darren Griffith et al.   CHEMICAL COMMUNICATIONS

Role of aromatic substituents on the antiproliferative effects of diphenyl ferrocenyl butene compounds

(2009) Ouardia Zekri et al.   DALTON TRANSACTIONS

Suberoylanilide hydroxamic acid (SAHA) potentiates paclitaxel-induced apoptosis in ovarian cancer cell lines

(2009) Charles S. Dietrich et al.   GYNECOLOGIC ONCOLOGY

Vorinostat increases carboplatin and paclitaxel activity in non-small cell lung cancer cells

(2009) Taofeek K. Owonikoko et al.   INTERNATIONAL JOURNAL OF CANCER

A [3]Ferrocenophane Polyphenol Showing a Remarkable Antiproliferative Activity on Breast and Prostate Cancer Cell Lines

(2009) Damian Plażuk et al.   JOURNAL OF MEDICINAL CHEMISTRY

Electrochemical parameters and techniques in drug development, with an emphasis on quinones and related compounds

(2008) Elizabeth Anne Hillard et al.   CHEMICAL COMMUNICATIONS

Synthesis and Structure-Activity Relationships of Ferrocenyl Tamoxifen Derivatives with Modified Side Chains

(2008) Anh Nguyen et al.   CHEMISTRY-A EUROPEAN JOURNAL

Inorganic chemical biology: from small metal complexes in biological systems to metalloproteins

(2008) Sheila S David et al.   CURRENT OPINION IN CHEMICAL BIOLOGY

Electrochemical attachment of a conjugated amino–ferrocifen complex onto carbon and metal surfaces

(2008) Olivier Buriez et al.   JOURNAL OF ELECTROANALYTICAL CHEMISTRY

Histone Deacetylase Inhibitors: From Bench to Clinic

(2008) Marielle Paris et al.   JOURNAL OF MEDICINAL CHEMISTRY

Use of the Nitrile Oxide Cycloaddition (NOC) Reaction for Molecular Probe Generation: A New Class of Enzyme Selective Histone Deacetylase Inhibitors (HDACIs) Showing Picomolar Activity at HDAC6

(2008) Alan P. Kozikowski et al.   JOURNAL OF MEDICINAL CHEMISTRY

The replacement of a phenol group by an aniline or acetanilide group enhances the cytotoxicity of 2-ferrocenyl-1,1-diphenyl-but-l-ene compounds against breast cancer cells

(2008) Pascal Pigeon et al.   JOURNAL OF ORGANOMETALLIC CHEMISTRY

Incorporation of histone deacetylase inhibition into the structure of a nuclear receptor agonist

(2008) L. E. Tavera-Mendoza et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA