γ-AApeptide-based small-molecule ligands that inhibit Aβ aggregation

Aβ42-Binding Peptoids as Amyloid Aggregation Inhibitors and Detection Ligands

(2013) Yuan Luo et al.   ACS Chemical Neuroscience

Radiolabeled γ-AApeptides: a new class of tracers for positron emission tomography

(2012) Yunan Yang et al.   CHEMICAL COMMUNICATIONS

Lipo-γ-AApeptides as a New Class of Potent and Broad-Spectrum Antimicrobial Agents

(2012) Youhong Niu et al.   JOURNAL OF MEDICINAL CHEMISTRY

Heterodivalent Linked Macrocyclic β-Sheets with Enhanced Activity against Aβ Aggregation: Two Sites Are Better Than One

(2012) Pin-Nan Cheng et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Nanorods Formed from a New Class of Peptidomimetics

(2012) Youhong Niu et al.   MACROMOLECULES

Amyloid β-sheet mimics that antagonize protein aggregation and reduce amyloid toxicity

(2012) Pin-Nan Cheng et al.   Nature Chemistry

Solid-Phase Synthesis of γ-AApeptides Using a Submonomeric Approach

(2012) Haifan Wu et al.   ORGANIC LETTERS

A cleavable scaffold strategy for the synthesis of one-bead one-compound cyclic peptoid libraries that can be sequenced by tandem mass spectrometry

(2012) Levi S. Simpson et al.   TETRAHEDRON LETTERS

Design and synthesis of unprecedented cyclic γ-AApeptides for antimicrobial development

(2012) Haifan Wu et al.   Chemical Science

Incorporation of Heterocycles into the Backbone of Peptoids to Generate Diverse Peptoid-Inspired One Bead One Compound Libraries

(2012) Animesh Aditya et al.   ACS Combinatorial Science

The rise, fall and reinvention of combinatorial chemistry

(2011) Thomas Kodadek   CHEMICAL COMMUNICATIONS

Identification of γ-AApeptides with potent and broad-spectrum antimicrobial activity

(2011) Youhong Niu et al.   CHEMICAL COMMUNICATIONS

Structural Basis for Increased Toxicity of Pathological Aβ42:Aβ40Ratios in Alzheimer Disease

(2011) Kris Pauwels et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

High-molecular weight Aβ oligomers and protofibrils are the predominant Aβ species in the native soluble protein fraction of the AD brain

(2011) Ajeet Rijal Upadhaya et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

A biomimetic polyketide-inspired approach to small-molecule ligand discovery

(2011) Claudio Aquino et al.   Nature Chemistry

γ-AApeptides: design, synthesis and evaluation

(2011) Youhong Niu et al.   NEW JOURNAL OF CHEMISTRY

γ-AApeptides bind to RNA by mimicking RNA-binding proteins

(2011) Youhong Niu et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Solid-phase synthesis and screening of N-acylated polyamine (NAPA) combinatorial libraries for protein binding

(2010) Jaclyn A. Iera et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Seamless Bead to Microarray Screening: Rapid Identification of the Highest Affinity Protein Ligands from Large Combinatorial Libraries

(2010) John M. Astle et al.   CHEMISTRY & BIOLOGY

Rethinking screening

(2010) Thomas Kodadek   Nature Chemical Biology

N-Acylpolyamine inhibitors of HDM2 and HDMX binding to p53

(2009) Ryo Hayashi et al.   BIOORGANIC & MEDICINAL CHEMISTRY