A biomimetic polyketide-inspired approach to small-molecule ligand discovery

1,3-Allylic Strain as a Strategic Diversification Element for Constructing Libraries of Substituted 2-Arylpiperidines

(2011) Thomas C. Coombs et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Identification of Candidate IgG Biomarkers for Alzheimer's Disease via Combinatorial Library Screening

(2011) M. Muralidhar Reddy et al.   CELL

Peptide Nucleic Acids (PNA) in Chemical Biology and Drug Discovery

(2010) Peter E. Nielsen   CHEMISTRY & BIODIVERSITY

Small molecules of different origins have distinct distributions of structural complexity that correlate with protein-binding profiles

(2010) P. A. Clemons et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Synthesis of Natural Product Inspired Compound Collections

(2009) Kamal Kumar et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

PRIMA-1 Reactivates Mutant p53 by Covalent Binding to the Core Domain

(2009) Jeremy M.R. Lambert et al.   CANCER CELL

Revisiting the modularity of modular polyketide synthases

(2009) Chaitan Khosla et al.   CURRENT OPINION IN CHEMICAL BIOLOGY

Allylic and Allenic Halide Synthesis via NbCl5- and NbBr5-Mediated Alkoxide Rearrangements

(2009) P. C. Ravikumar et al.   JOURNAL OF ORGANIC CHEMISTRY

Gold(I)-Catalyzed Coupling Reactions for the Synthesis of Diverse Small Molecules Using the Build/Couple/Pair Strategy

(2009) Tuoping Luo et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Skeletally Diverse Small Molecules Using a Build/Couple/Pair Strategy

(2009) Takuya Uchida et al.   ORGANIC LETTERS

β-Peptidic Peptidomimetics

(2008) Dieter Seebach et al.   ACCOUNTS OF CHEMICAL RESEARCH

Shape-Programmable Macromolecules

(2008) Christian E. Schafmeister et al.   ACCOUNTS OF CHEMICAL RESEARCH

α-Aminoxy Acids: New Possibilities from Foldamers to Anion Receptors and Channels

(2008) Xiang Li et al.   ACCOUNTS OF CHEMICAL RESEARCH

β-Hairpin Peptidomimetics: Design, Structures and Biological Activities

(2008) John A. Robinson   ACCOUNTS OF CHEMICAL RESEARCH

Foldamers with Heterogeneous Backbones

(2008) W. Seth Horne et al.   ACCOUNTS OF CHEMICAL RESEARCH

Exploring β-Sheet Structure and Interactions with Chemical Model Systems

(2008) James S. Nowick   ACCOUNTS OF CHEMICAL RESEARCH

Synthesis of Natural-Product-Like Molecules with Over Eighty Distinct Scaffolds

(2008) Daniel Morton et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

A Peptoid “Antibody Surrogate” That Antagonizes VEGF Receptor 2 Activity

(2008) D. Gomika Udugamasooriya et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Targeted rescue of a destabilized mutant of p53 by an in silico screened drug

(2008) F. M. Boeckler et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Chemical Versatility of Natural-Product Assembly Lines

(2007) Christopher T. Walsh   ACCOUNTS OF CHEMICAL RESEARCH

Towards the Optimal Screening Collection: A Synthesis Strategy

(2007) Thomas E. Nielsen et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION