Enantioselective synthesis of benzazepinoindoles bearing trifluoromethylated quaternary stereocenters catalyzed by chiral spirocyclic phosphoric acids

Hydrogenative Dearomatization of Pyridine and an Asymmetric Aza-Friedel-Crafts Alkylation Sequence

(2014) Shuo-Guo Wang et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Pd(0)-Catalyzed Tandem Deprotection/Cyclization of Tetrahydro-β-carbolines on Allenes: Application to the Synthesis of Indolo[2,3-a]quinolizidines

(2014) Valerian Gobé et al.   ORGANIC LETTERS

Diastereoselective and Enantioselective Epoxidation of Acyclic β-Trifluoromethyl-β,β-Disubstituted Enones by Hydrogen Peroxide with a Pentafluorinated Quinidine-Derived Phase-Transfer Catalyst

(2013) Shaoxiang Wu et al.   ADVANCED SYNTHESIS & CATALYSIS

Enantio- and Diastereoselective Assembly of Tetrahydrofuran and Tetrahydropyran Skeletons with All-Carbon-Substituted Quaternary Stereocenters

(2013) Zhilong Chen et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Complex Bioactive Alkaloid-Type Polycycles through Efficient Catalytic Asymmetric Multicomponent Aza-Diels-Alder Reaction of Indoles with Oxetane as Directing Group

(2013) Zhilong Chen et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Catalytic Enantioselective Intermolecular Desymmetrization of 3-Substituted Oxetanes

(2013) Zhaobin Wang et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Versatile Access to Chiral Indolines by Catalytic Asymmetric Fischer Indolization

(2013) Alberto Martínez et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Enantioselective Synthesis of Epoxides Having a Tetrasubstituted Trifluoromethylated Carbon Center: Methylhydrazine-Induced Aerobic Epoxidation of β,β-Disubstituted Enones

(2013) Hiroyuki Kawai et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Organocatalytic asymmetric multicomponent reactions of aromatic aldehydes and anilines with β-ketoesters: facile and atom-economical access to chiral tetrahydropyridines

(2013) Xuejian Li et al.   CHEMICAL COMMUNICATIONS

Catalytic Enantioselective Synthesis of Tetrahydroisoquinolines and Their Analogues Bearing a C4 Stereocenter: Formal Synthesis of (+)-(8S,13R)-Cyclocelabenzine

(2013) Zhilong Chen et al.   CHEMISTRY-A EUROPEAN JOURNAL

Theoretical Study on the Acidities of Chiral Phosphoric Acids in Dimethyl Sulfoxide: Hints for Organocatalysis

(2013) Chen Yang et al.   JOURNAL OF ORGANIC CHEMISTRY

Organocatalytic Cascade Sulfa-Michael/Aldol Reaction of β,β-Disubstituted Enones: Enantioselective Synthesis of Tetrahydrothiophenes with a Trifluoromethylated Quaternary Center

(2013) Yu Su et al.   JOURNAL OF ORGANIC CHEMISTRY

Catalytic Asymmetric Protonation of Silyl Ketene Imines

(2013) Joyram Guin et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

An olefin isomerization/asymmetric Pictet–Spengler cascade via sequential catalysis of ruthenium alkylidene and chiral phosphoric acid

(2013) Quan Cai et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

A combination of directing groups and chiral anion phase-transfer catalysis for enantioselective fluorination of alkenes

(2013) Jeffrey Wu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Highly enantioselective S–H bond insertion cooperatively catalyzed by dirhodium complexes and chiral spiro phosphoric acids

(2013) Bin Xu et al.   Chemical Science

Highly Enantioselective Synthesis of Dihydroquinazolinones Catalyzed by SPINOL-Phosphoric Acids

(2013) Dan Huang et al.   ACS Catalysis

Highly enantioselective hydrophosphonylation of imines catalyzed by SPINOL-phosphoric acid

(2013) Yanyan Zhao et al.   RSC Advances

Organocatalytic Asymmetric Synthesis of Trifluoromethyl-substituted Diarylpyrrolines: Enantioselective Conjugate Cyanation of β-Aryl-β-trifluoromethyl-disubstituted Enones

(2012) Hiroyuki Kawai et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Highly Enantioselective Pictet-Spengler Reaction Catalyzed by SPINOL-Phosphoric Acids

(2012) Dan Huang et al.   CHEMISTRY-A EUROPEAN JOURNAL

Asymmetric Allylboration of Aldehydes with Pinacol Allylboronates Catalyzed by 1,1′-Spirobiindane-7,7′-diol (SPINOL) Based Phosphoric Acids

(2012) Chun-Hui Xing et al.   EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

Oxidative γ-Addition of Enals to Trifluoromethyl Ketones: Enantioselectivity Control via Lewis Acid/N-Heterocyclic Carbene Cooperative Catalysis

(2012) Junming Mo et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

An Asymmetric Synthesis of 1,2,4-Trioxane Anticancer Agents via Desymmetrization of Peroxyquinols through a Brønsted Acid Catalysis Cascade

(2012) David M. Rubush et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Highly Enantioselective Copper-Catalyzed Electrophilic Trifluoromethylation of β-Ketoesters

(2012) Qing-Hai Deng et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Highly enantioselective Biginelli reaction catalyzed by SPINOL-phosphoric acids

(2012) Fangxi Xu et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Direct and Highly Enantioselective Iso-Pictet–Spengler Reactions with α-Ketoamides: Access to Underexplored Indole Core Structures

(2012) Heike Schönherr et al.   ORGANIC LETTERS

Highly enantioselective three-component Povarov reaction catalyzed by SPINOL-phosphoric acids

(2012) Dan Huang et al.   RSC Advances

Brønsted-Acid-Catalyzed Asymmetric Multicomponent Reactions for the Facile Synthesis of Highly Enantioenriched Structurally Diverse Nitrogenous Heterocycles

(2011) Jie Yu et al.   ACCOUNTS OF CHEMICAL RESEARCH

An Easy Entry to Optically Active Spiroindolinones: Chiral Brønsted Acid-Catalysed Pictet-Spengler Reactions of Isatins

(2011) Sara Duce et al.   ADVANCED SYNTHESIS & CATALYSIS

Asymmetric NH Insertion Reaction Cooperatively Catalyzed by Rhodium and Chiral Spiro Phosphoric Acids

(2011) Bin Xu et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Bifunctional Cinchona Alkaloid Thiourea Catalyzed Highly Efficient, Enantioselective Aza-Henry Reaction of Cyclic Trifluoromethyl Ketimines: Synthesis of Anti-HIV Drug DPC 083

(2011) Hexin Xie et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

The Pictet-Spengler Reaction in Nature and in Organic Chemistry

(2011) Joachim Stöckigt et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Asymmetric Organocatalytic Cyclization and Cycloaddition Reactions

(2011) Albert Moyano et al.   CHEMICAL REVIEWS

Chiral Brønsted acids in enantioselective carbonyl activations – activation modes and applications

(2011) Magnus Rueping et al.   CHEMICAL SOCIETY REVIEWS

Enantioselective Organocatalytic Synthesis of Fluorinated Molecules

(2011) Guillem Valero et al.   CHEMISTRY-A EUROPEAN JOURNAL

Optically Active 1,1′-Spirobiindane-7,7′-diol (SPINOL)-Based Phosphoric Acids as Highly Enantioselective Catalysts for Asymmetric Organocatalysis

(2011) Chun-Hui Xing et al.   JOURNAL OF ORGANIC CHEMISTRY

The Catalytic Asymmetric Fischer Indolization

(2011) Steffen Müller et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Direct Synthesis of Chiral 1,2,3,4-Tetrahydropyrrolo[1,2-a]pyrazines via a Catalytic Asymmetric Intramolecular Aza-Friedel–Crafts Reaction

(2011) Yuwei He et al.   ORGANIC LETTERS

Thiourea-Catalyzed Enantioselective Iso-Pictet–Spengler Reactions

(2011) Yunmi Lee et al.   ORGANIC LETTERS

Catalytic Asymmetric Pictet–Spengler-Type Reaction for the Synthesis of Optically Active Indolo[3,4-cd][1]benzazepines

(2011) Dao-Juan Cheng et al.   ORGANIC LETTERS

Synthesis of Trifluoromethylated and gem-Difluoromethylenated Biologically Interesting Compounds from Fluorine-Containing Synthons

(2011) Feng-Ling Qing et al.   SYNLETT

Combination Catalysis in Enantioselective Trifluoromethylation

(2010) Yan Zheng et al.   ADVANCED SYNTHESIS & CATALYSIS

Asymmetric Construction of Stereogenic Carbon Centers Featuring a Trifluoromethyl Group from Prochiral Trifluoromethylated Substrates

(2010) Jing Nie et al.   CHEMICAL REVIEWS

SPINOL-Derived Phosphoric Acids: Synthesis and Application in Enantioselective Friedel−Crafts Reaction of Indoles with Imines

(2010) Fangxi Xu et al.   JOURNAL OF ORGANIC CHEMISTRY

Kinetic Resolution of Homoaldols via Catalytic Asymmetric Transacetalization

(2010) Ilija Čorić et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Organocatalytic Asymmetric Synthesis of Chiral Pyrrolizines by Cascade Conjugate Addition−Aldol Reactions

(2010) Ju-Yeon Bae et al.   ORGANIC LETTERS

Direct Enantioselective Brønsted Acid CatalyzedN-Acyliminium Cyclization Cascades of Tryptamines and Ketoacids

(2010) Chloe A. Holloway et al.   ORGANIC LETTERS

Highly Enantioselective Pictet-Spengler Reactions with α-Ketoamide-Derived Ketimines: Access to an Unusual Class of Quaternary α-Amino Amides

(2009) Farhan R. Bou-Hamdan et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

A perfect double role of CF3 groups in activating substrates and stabilizing adducts: the chiral Brønsted acid-catalyzed direct arylation of trifluoromethyl ketones

(2009) Jing Nie et al.   CHEMICAL COMMUNICATIONS

Highly enantio- and diastereoselective synthesis of α-trifluoromethyldihydropyrans using a novel bifunctional piperazine-thiourea catalyst

(2009) Peng Li et al.   CHEMICAL COMMUNICATIONS

Application of 7-endo-trigPictet-Spengler Cyclization to the Formation of the Benzazepine Ring: Synthesis of Benzazepinoindoles

(2009) Sudhir K. Sharma et al.   EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

Synthesis of fluorinated chiral amines usingN-tert-butylsulfinyl imines

(2009) Jun Liu et al.   Future Medicinal Chemistry

DFT Study on the Factors Determining the Enantioselectivity of Friedel−Crafts Reactions of Indole withN-Acyl andN-Tosylimines Catalyzed by BINOL−Phosphoric Acid Derivatives

(2009) Luis Simón et al.   JOURNAL OF ORGANIC CHEMISTRY

Enantioselective Brønsted Acid-CatalyzedN-Acyliminium Cyclization Cascades

(2009) Michael E. Muratore et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Weak Brønsted Acid−Thiourea Co-catalysis: Enantioselective, Catalytic Protio-Pictet−Spengler Reactions

(2009) Rebekka S. Klausen et al.   ORGANIC LETTERS

Recent advances in enantioselective trifluoromethylation reactions

(2009) Norio Shibata et al.   TETRAHEDRON-ASYMMETRY

Binaphthol-derived phosphoric acid as a versatile catalyst for enantioselective carbon–carbon bond forming reactions

(2008) Masahiro Terada   CHEMICAL COMMUNICATIONS

Update 1 of: Asymmetric Fluorination, Trifluoromethylation, and Perfluoroalkylation Reactions

(2008) Jun-An Ma et al.   CHEMICAL REVIEWS

Fluorine in medicinal chemistry

(2007) Sophie Purser et al.   CHEMICAL SOCIETY REVIEWS