Article
Chemistry, Organic
Liu Shi, Qiang Xiong, Shu-Yi Wu, Yang Li, Peng Shen, Ji Lu, Guang-Yao Ran
Summary: Novel cyclic vinylogous anhydrides were designed and utilized as five-carbon carbonyl synthons for [5 + 5] annulation with vinylethylene carbonates under chiral palladium catalysis. The strategy exhibited excellent regioselectivity, mild conditions, and broad substrate scope, leading to the synthesis of spiro ten-membered lactones bearing oxindole and pyrrolidinone motif in high yield (up to 99%) with moderate to high enantioselectivity (up to 89% ee).
Article
Chemistry, Organic
Srinivasarao Yaragorla, Doma Arun
Summary: We present a strategy for the direct synthesis of C2-aryl/heteroaryl indoles without the use of transition metal catalysts. The synthesis involves a one-pot, four-component reaction using readily available starting materials, which allows for the generation of diverse indole derivatives with a broad range of substrates and high yields. The reaction proceeds through a series of steps including Friedel-Crafts C-arylation, N-arylation, [3+2] cycloaddition, and aromatization cascade.
JOURNAL OF ORGANIC CHEMISTRY
(2022)
Article
Chemistry, Organic
Yotsakorn Saebang, Juthanat Kaeobamrung, Vatcharin Rukachaisirikul
Summary: The straightforward synthesis of quinazolinones with N-fused medium-sized ring urea was achieved, involving key intermediates tert-butyl {2-[4-oxo-2-(4-oxopentyl)quinazolin-3(4H)-yl]ethyl]carbamates derived from copper-catalyzed domino reaction and direct cyclization using 1,1'-carbonyldiimidazole (CDI).
Article
Chemistry, Inorganic & Nuclear
Jose-Antonio Garcia-Lopez, Maria-Jose Oliva-Madrid, Delia Bautista, Jose Vicente, Isabel Saura-Llamas
Summary: This study involves the synthesis of metallacycles by inserting alkynes into Pd-C bonds of ortho-metalated homoveratrylamine and phentermine, which further react with alkenes to form mononuclear complexes. Depending on the type of olefin used, different types of Pd(II) complexes are obtained. When terminal alkenes are used, anti/syn eta(3)-allyl Pd(II) complexes are formed; whereas using 2-norbornene leads to the formation of norbornyl palladium(II) complexes with a 10-membered ring structure.
Review
Medicine, General & Internal
Rehab Y. Al-Ansari, Dena Al Otaibi, Nourah Al Hudaithi, Leena Abdalla
Summary: Essential thrombocythemia is a myeloproliferative disorder commonly caused by genetic mutations such as JAK2, MPL, and CALR. Isolated TET2 positive in triple negative essential thrombocythemia is rare. Further study and guidelines are needed to understand the management and risk stratification in this condition.
SAGE OPEN MEDICAL CASE REPORTS
(2021)
Article
Chemistry, Multidisciplinary
Alberto Martinez-Cuezva, Delia Bautista, Mateo Alajarin, Jose Berna
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
(2018)
Article
Chemistry, Organic
Adrian Saura-Sanmartin, Alberto Martinez-Cuezva, Aurelia Pastor, Delia Bautista, Jose Berna
ORGANIC & BIOMOLECULAR CHEMISTRY
(2018)
Article
Chemistry, Inorganic & Nuclear
Marta Perez-Gomez, Sergio Hernandez-Ponte, Jose Antonio Garcia-Lopez, Roberto Frutos-Pedreno, Delia Bautista, Isabel Saura-Llamas, Jose Vicente
Article
Chemistry, Multidisciplinary
Angela Vivancos, Delia Bautista, Pablo Gonzalez-Herrero
CHEMISTRY-A EUROPEAN JOURNAL
(2019)
Article
Chemistry, Inorganic & Nuclear
Maria-Teresa Chicote, Isabel Saura-Llamas, Maria-Francisca Garcia-Yuste, Delia Bautista, Jose Vicente
JOURNAL OF ORGANOMETALLIC CHEMISTRY
(2019)
Article
Chemistry, Inorganic & Nuclear
Jose-Antonio Garcia-Lopez, Maria-Jose Oliva-Madrid, Delia Bautista, Jose Vicente, Isabel Saura-Llamas
Summary: This study involves the synthesis of metallacycles by inserting alkynes into Pd-C bonds of ortho-metalated homoveratrylamine and phentermine, which further react with alkenes to form mononuclear complexes. Depending on the type of olefin used, different types of Pd(II) complexes are obtained. When terminal alkenes are used, anti/syn eta(3)-allyl Pd(II) complexes are formed; whereas using 2-norbornene leads to the formation of norbornyl palladium(II) complexes with a 10-membered ring structure.
Article
Chemistry, Inorganic & Nuclear
Angela Vivancos, Adrian Jimenez-Garcia, Delia Bautista, Pablo Gonzalez-Herrero
Summary: A series of bis-cyclometalated Pt(IV) complexes incorporating mesoionic aryl-NHC ligand trz with either 1-phenylpyrazole or 2-arylpyridine ligands are reported, showing phosphorescent emissions in the blue to yellow color range with high quantum yields. The addition of trz ligand leads to lower nonradiative decay rates and higher quantum efficiencies compared to homologous species with two equal 2-arylpyridine ligands. Computational calculations substantiate the effect of the carbene ligand on the energy levels and emissive properties of the complexes.
INORGANIC CHEMISTRY
(2021)
Review
Chemistry, Inorganic & Nuclear
Jose-Antonio Garcia-Lopez, Isabel Saura-Llamas
Summary: This manuscript reviews different approaches for the synthesis of C,C-palladacycles and their relevance in catalytic transformations. The strategies include elemental steps like oxidative addition of C-C bonds and more complex processes involving multiple Pd chemistry steps. Furthermore, it highlights synthetic methodologies based on Pd catalysis with C,C-palladacyclic intermediates.
EUROPEAN JOURNAL OF INORGANIC CHEMISTRY
(2021)
Article
Chemistry, Multidisciplinary
Dionisio Poveda, Angela Vivancos, Delia Bautista, Pablo Gonzalez-Herrero
Article
Chemistry, Multidisciplinary
Francisco J. Ballester, Enrique Ortega, Delia Bautista, M. Dolores Santana, Jose Ruiz
CHEMICAL COMMUNICATIONS
(2020)
Article
Chemistry, Inorganic & Nuclear
Angela Vivancos, Dionisio Poveda, Alonso Munoz, Julia Moreno, Delia Bautista, Pablo Gonzalez-Herrero
DALTON TRANSACTIONS
(2019)
Review
Chemistry, Multidisciplinary
Juan Gil-Rubio, Jose Vicente
CHEMISTRY-A EUROPEAN JOURNAL
(2018)
Review
Chemistry, Multidisciplinary
Dan He, Yawen Li, Fuwen Zhao, Yuze Lin
Summary: High trap density in organic solar cells leads to localized charge carriers and reduced carrier lifetime, limiting device efficiency. This feature article summarizes the recent advances of trap suppression by material design and device engineering.
CHEMICAL COMMUNICATIONS
(2024)
Review
Chemistry, Multidisciplinary
Olivier Monfort, Arshitha Madhusudhan, Martin Motola
Summary: This article presents the advantages of coupling photocatalysis and Fenton-based processes for environmental remediation and discusses their synergy. It critically examines the simultaneous triggering of these two processes and provides insights into research approaches. The study aims to enhance understanding of this complex process and highlight the potential integration of new catalysts in current wastewater treatment technology.
CHEMICAL COMMUNICATIONS
(2024)
Article
Chemistry, Multidisciplinary
Manideepa Dhar, Chittaranjan Mishra, Avijit Das, Uttam Manna
Summary: An approach of 'polymerization of monomers in its aggregated form' has been introduced to tailor the water wettability of fibrous and porous substrates, achieving hydrophobicity to superhydrophobicity transition, as well as patterned wettability. This facile chemical method provides a durable coating with adjustable and patterned wettability for various potential applications.
CHEMICAL COMMUNICATIONS
(2024)
Article
Chemistry, Multidisciplinary
Saswat Ranjan Bhoi, Chhanda Debnath, Shikha Gandhi
Summary: In this article, a novel catalytic reaction using Pd(0) and Bronsted acid is reported for the synthesis of biologically important imidazolidinone-fused N-heterocycles through redox-neutral intramolecular N-allylation of indoles and pyrroles with alkynes. This atom-economical method is applicable to a wide range of substrates and eliminates the need for leaving groups or oxidizing agents commonly used in traditional allylation reactions.
CHEMICAL COMMUNICATIONS
(2024)
Article
Chemistry, Multidisciplinary
Longkun Chen, Mingshuai Zhang, Meichen Liu, Zhuoyuan Liu, Yuetong Qiu, Zhilai Zhang, Fuchao Yu, Jiuzhong Huang
Summary: In this study, an efficient Rh(III)-catalyzed selective mono- and dual-C-H bond functionalization/cyclization with iodonium ylide as the sole coupling partner was demonstrated. Fused benzodiazepine skeletons were obtained in excellent yields, providing an improved approach to dual C-H unsymmetrical functionalization.
CHEMICAL COMMUNICATIONS
(2024)
Article
Chemistry, Multidisciplinary
Alice Kennett, Sven Epple, Gabriella van der Valk, Irene Georgiou, Evelyne Gout, Romain R. Vives, Angela J. Russell
Summary: This study presents the design and synthesis of sulfated disaccharide inhibitors based on IdoA(2S)-GlcNS(6S), which showed potent inhibition of Sulf-2. The results suggest that IdoA(2S)-GlcNS(6S) is the shortest fragment size required for effective inhibition of Sulfs, and a trisulfated disaccharide is identified as the minimal fragment size of heparan sulfate for effective endosulfatase inhibition.
CHEMICAL COMMUNICATIONS
(2024)
Article
Chemistry, Multidisciplinary
Mauro Garbini, Andrea Brunetti, Riccardo Pedrazzani, Magda Monari, Massimo Marcaccio, Giulio Bertuzzi, Marco Bandini
Summary: The self-adaptability of galvanostatic electrolysis was found to be helpful in a multistage chemo- and diastereoselective electrochemically promoted cyclodimerization of chalcones. Through a series of reductive events, densely functionalized cyclopentanes with five contiguous stereocenters were obtained (25 examples, yields up to 95%, dr values up to >20:1). Further experimental and electrochemical investigations indicated the crucial role of dynamic kinetic resolution of the aldol intermediate in the reaction mechanism.
CHEMICAL COMMUNICATIONS
(2024)
Article
Chemistry, Multidisciplinary
Dhananjay S. Nipate, Neha Meena, Prakash N. Swami, Krishnan Rangan, Anil Kumar
Summary: In this study, the synthesis of functionalized benzo[a]phenazines and indazolo[2,3-a]quinolines was achieved through Rh(III)-catalyzed oxidative annulation of 2-arylquinoxalines and 2-aryl-2H-indazoles with allyl alcohols. The method showed a wide substrate scope, excellent functional group tolerance, good to high yields of annulated products, and the capability for scaled-up synthesis. A tentative mechanism of the annulation reaction was proposed based on a preliminary mechanistic investigation.
CHEMICAL COMMUNICATIONS
(2024)
Article
Chemistry, Multidisciplinary
Ruonan Zhang, Abudukadi Tudi, Xia Yang, Xuping Wang, Zhihua Yang, Shujuan Han, Shilie Pan
Summary: A new lead tellurium borate material with a unique fundamental building block [B4O10] was synthesized and found to exhibit high birefringence. The structure-property relationship was discussed using first-principles calculations.
CHEMICAL COMMUNICATIONS
(2024)
Article
Chemistry, Multidisciplinary
Amresh Kumar Singh, Baishali Thakurta, Anupam Giri, Monalisa Pal
Summary: This study introduces three key concepts for the quick synthesis of large-scale high-quality 2D materials films and their utilization in device fabrication.
CHEMICAL COMMUNICATIONS
(2024)
Article
Chemistry, Multidisciplinary
Reina Hagiwara, Shun Nishimura, Kosuke Okeyoshi
Summary: A copolymer-conjugated nanocatalytic system has been developed to improve electron transfer and enhance photoinduced H2 generation.
CHEMICAL COMMUNICATIONS
(2024)
