Dithiocarbamates: a new class of carbonic anhydrase inhibitors. Crystallographic and kinetic investigations
Published 2011 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Dithiocarbamates: a new class of carbonic anhydrase inhibitors. Crystallographic and kinetic investigations
Authors
Keywords
-
Journal
CHEMICAL COMMUNICATIONS
Volume 48, Issue 13, Pages 1868
Publisher
Royal Society of Chemistry (RSC)
Online
2011-12-14
DOI
10.1039/c2cc16395k
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Targeting Tumor Hypoxia: Suppression of Breast Tumor Growth and Metastasis by Novel Carbonic Anhydrase IX Inhibitors
- (2011) Y. Lou et al. CANCER RESEARCH
- Interfering with pH regulation in tumours as a therapeutic strategy
- (2011) Dario Neri et al. NATURE REVIEWS DRUG DISCOVERY
- Coumarinyl-substituted sulfonamides strongly inhibit several human carbonic anhydrase isoforms: solution and crystallographic investigations
- (2010) Jason Wagner et al. BIOORGANIC & MEDICINAL CHEMISTRY
- Carbonic anhydrase inhibitors. Inhibition of transmembrane isoforms IX, XII, and XIV with less investigated anions including trithiocarbonate and dithiocarbamate
- (2010) Alessio Innocenti et al. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
- 7,8-Disubstituted- but not 6,7-disubstituted coumarins selectively inhibit the transmembrane, tumor-associated carbonic anhydrase isoforms IX and XII over the cytosolic ones I and II in the low nanomolar/subnanomolar range
- (2010) Alfonso Maresca et al. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
- Carbonic anhydrase inhibitors
- (2010) Claudiu T. Supuran BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
- Carbonic anhydrase inhibitors. The X-ray crystal structure of human isoform II in adduct with an adamantyl analogue of acetazolamide resides in a less utilized binding pocket than most hydrophobic inhibitors
- (2010) Balendu Sankara Avvaru et al. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
- Coumarins incorporating hydroxy- and chloro-moieties selectively inhibit the transmembrane, tumor-associated carbonic anhydrase isoforms IX and XII over the cytosolic ones I and II
- (2010) Alfonso Maresca et al. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
- Selective hydrophobic pocket binding observed within the carbonic anhydrase II active site accommodate different 4-substituted-ureido-benzenesulfonamides and correlate to inhibitor potency
- (2010) Fabio Pacchiano et al. CHEMICAL COMMUNICATIONS
- Bidentate Zinc Chelators for α-Carbonic Anhydrases that Produce a Trigonal Bipyramidal Coordination Geometry
- (2010) Johannes Schulze Wischeler et al. ChemMedChem
- Carbonic Anhydrase Inhibition/Activation: Trip of a Scientist Around the World in the Search of Novel Chemotypes and Drug Targets
- (2010) Claudiu T. Supuran CURRENT PHARMACEUTICAL DESIGN
- Potent inhibitory effects of benzyl andp-xylidine-bis dithiocarbamate sodium salts on activities of mushroom tyrosinase
- (2010) E. Amin et al. JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY
- Polyamines Inhibit Carbonic Anhydrases by Anchoring to the Zinc-Coordinated Water Molecule
- (2010) Fabrizio Carta et al. JOURNAL OF MEDICINAL CHEMISTRY
- Carbonic anhydrase inhibitors. Inhibition of cytosolic isoforms I, II, III, VII and XIII with less investigated inorganic anions
- (2009) Alessio Innocenti et al. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
- Carbonic anhydrase inhibitors. X-ray crystal studies of the carbonic anhydrase II–trithiocarbonate adduct—An inhibitor mimicking the sulfonamide and urea binding to the enzyme
- (2009) Claudia Temperini et al. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
- Taking advantage of tumor cell adaptations to hypoxia for developing new tumor markers and treatment strategies
- (2009) Peter Ebbesen et al. JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY
- Deciphering the Mechanism of Carbonic Anhydrase Inhibition with Coumarins and Thiocoumarins
- (2009) Alfonso Maresca et al. JOURNAL OF MEDICINAL CHEMISTRY
- Non-Zinc Mediated Inhibition of Carbonic Anhydrases: Coumarins Are a New Class of Suicide Inhibitors#
- (2009) Alfonso Maresca et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Crystal structure of the catalytic domain of the tumor-associated human carbonic anhydrase IX
- (2009) V. Alterio et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Entrapment of Carbon Dioxide in the Active Site of Carbonic Anhydrase II
- (2008) John F. Domsic et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Carbonic anhydrases: novel therapeutic applications for inhibitors and activators
- (2008) Claudiu T. Supuran NATURE REVIEWS DRUG DISCOVERY
- Crystal structure of human carbonic anhydrase XIII and its complex with the inhibitor acetazolamide
- (2008) Anna Di Fiore et al. PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS
Become a Peeref-certified reviewer
The Peeref Institute provides free reviewer training that teaches the core competencies of the academic peer review process.
Get StartedAsk a Question. Answer a Question.
Quickly pose questions to the entire community. Debate answers and get clarity on the most important issues facing researchers.
Get Started