A general synthesis of dirhodium metallopeptides as MDM2 ligands

Synthesis of cell-permeable stapled peptide dual inhibitors of the p53-Mdm2/Mdmx interactions via photoinduced cycloaddition

(2011) Michael M. Madden et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Chemical states of the N-terminal “lid” of MDM2 regulate p53 binding: Simulations reveal complexities of modulation

(2011) Shubhra Ghosh Dastidar et al.   CELL CYCLE

Proximity-driven metallopeptide catalysis: Remarkable side-chain scope enables modification of the Fos bZip domain

(2011) Brian V. Popp et al.   Chemical Science

High affinity interaction of the p53 peptide-analogue with human Mdm2 and Mdmx

(2010) Anna Czarna et al.   CELL CYCLE

Helix Induction by Dirhodium: Access to Biocompatible Metallopeptides with Defined Secondary Structure

(2010) Alexander N. Zaykov et al.   CHEMISTRY-A EUROPEAN JOURNAL

Photophysical Properties, DNA Photocleavage, and Photocytotoxicity of a Series of Dppn Dirhodium(II,II) Complexes

(2010) Lauren E. Joyce et al.   INORGANIC CHEMISTRY

Novel Helix-Constrained Nociceptin Derivatives Are Potent Agonists and Antagonists of ERK Phosphorylation and Thermal Analgesia in Mice

(2010) Rosemary S. Harrison et al.   JOURNAL OF MEDICINAL CHEMISTRY

Structure-Selective Modification of Aromatic Side Chains with Dirhodium Metallopeptide Catalysts

(2010) Brian V. Popp et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Peptides for In Vivo Target-Specific Cancer Imaging

(2010) G. Ferro-Flores et al.   MINI-REVIEWS IN MEDICINAL CHEMISTRY

Reactivation of p53: from peptides to small molecules

(2010) Christopher J. Brown et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

Copper(I)-mediated protein–protein interactions result from suboptimal interaction surfaces

(2009) Lucia Banci et al.   BIOCHEMICAL JOURNAL

Controlling Peptide Structure with Coordination Chemistry: Robust and Reversible Peptide-Dirhodium Ligation

(2009) Alexander N. Zaykov et al.   CHEMISTRY-A EUROPEAN JOURNAL

Anticancer activity of heteroleptic diimine complexes of dirhodium: A study of intercalating properties, hydrophobicity and in cellulo activity

(2009) J. Dafhne Aguirre et al.   DALTON TRANSACTIONS

Metal Clips That Induce Unstructured Pentapeptides To Be α-Helical In Water

(2009) Michelle T. Ma et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Live Cell Cytotoxicity Studies: Documentation of the Interactions of Antitumor Active Dirhodium Compounds with Nuclear DNA

(2009) J. Dafhne Aguirre et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Linkage Isomerism in the Binding of Pentapeptide Ac-His(Ala)3His-NH2to (Ethylenediamine)Palladium(II): Effect of the Binding Mode on Peptide Conformation

(2008) Huy N. Hoang et al.   INORGANIC CHEMISTRY

BCL-2 family antagonists for cancer therapy

(2008) Guillaume Lessene et al.   NATURE REVIEWS DRUG DISCOVERY