Genetic Encoding of Caged Cysteine and Caged Homocysteine in Bacterial and Mammalian Cells

Pyrrolysyl-tRNA synthetase: An ordinary enzyme but an outstanding genetic code expansion tool

(2014) Wei Wan et al.   BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS

Genetic Encoding of Photocaged Cysteine Allows Photoactivation of TEV Protease in Live Mammalian Cells

(2014) Duy P. Nguyen et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Structural Insights into Incorporation of Norbornene Amino Acids for Click Modification of Proteins

(2013) Sabine Schneider et al.   CHEMBIOCHEM

Genetically Encoded Light-Activated Transcription for Spatiotemporal Control of Gene Expression and Gene Silencing in Mammalian Cells

(2013) James Hemphill et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Mechanism-Based Design of a Photoactivatable Firefly Luciferase

(2013) Jingyi Zhao et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

In Vivo Expression of a Light-Activatable Potassium Channel Using Unnatural Amino Acids

(2013) Ji-Yong Kang et al.   NEURON

Diverse Functional Roles of Reactive Cysteines

(2012) Nicholas J. Pace et al.   ACS Chemical Biology

A novel crystal form of pyrrolysyl-tRNA synthetase reveals the pre- and post-aminoacyl-tRNA synthesis conformational states of the adenylate and aminoacyl moieties and an asparagine residue in the catalytic site

(2012) Tatsuo Yanagisawa et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Chemistry and Biology of the Ubiquitin Signal

(2012) Liat Spasser et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Site-Specific Incorporation of ε-N-Crotonyllysine into Histones

(2012) Chan Hyuk Kim et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Light-Controlled Tools

(2012) Clara Brieke et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Disulfide Bonding in Protein Biophysics

(2012) Deborah Fass   Annual Review of Biophysics

Cell signalling by reactive lipid species: new concepts and molecular mechanisms

(2012) Ashlee Higdon et al.   BIOCHEMICAL JOURNAL

Light-controlled synthetic gene circuits

(2012) Laura Gardner et al.   CURRENT OPINION IN CHEMICAL BIOLOGY

Amino-terminal Cysteine Residues Differentially Influence RGS4 Protein Plasma Membrane Targeting, Intracellular Trafficking, and Function

(2012) Guillaume Bastin et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Mitochondrial redox signalling at a glance

(2012) Yvonne Collins et al.   JOURNAL OF CELL SCIENCE

Magnesium Ion–Water Coordination and Exchange in Biomolecular Simulations

(2012) Olof Allnér et al.   Journal of Chemical Theory and Computation

Photocontrol of Tyrosine Phosphorylation in Mammalian Cells via Genetic Encoding of Photocaged Tyrosine

(2012) Eyal Arbely et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

A Rationally Designed Pyrrolysyl-tRNA Synthetase Mutant with a Broad Substrate Spectrum

(2012) Yane-Shih Wang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Genetically encoded norbornene directs site-specific cellular protein labelling via a rapid bioorthogonal reaction

(2012) Kathrin Lang et al.   Nature Chemistry

Stereochemical Basis for Engineered Pyrrolysyl-tRNA Synthetase and the Efficientin VivoIncorporation of Structurally Divergent Non-native Amino Acids

(2011) Jeffrey K. Takimoto et al.   ACS Chemical Biology

Light-Activated Gene Editing with a Photocaged Zinc-Finger Nuclease

(2011) Chungjung Chou et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

The Disulfide Proteome and Other Reactive Cysteine Proteomes: Analysis and Functional Significance

(2011) Marika Lindahl et al.   ANTIOXIDANTS & REDOX SIGNALING

Probing Intein-Catalyzed Thioester Formation by Unnatural Amino Acid Substitutions in the Active Site

(2011) Dirk Schwarzer et al.   BIOCHEMISTRY

Thiolactone modulators of quorum sensing revealed through library design and screening

(2011) Christine E. McInnis et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Light-Activated Kinases Enable Temporal Dissection of Signaling Networks in Living Cells

(2011) Arnaud Gautier et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Expanding the Genetic Code of an Animal

(2011) Sebastian Greiss et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Thiol-Based Redox Switches and Gene Regulation

(2010) Haike Antelmann et al.   ANTIOXIDANTS & REDOX SIGNALING

A Genetically Encoded ε-N-Methyl Lysine in Mammalian Cells

(2010) Dan Groff  et al.   CHEMBIOCHEM

Photocaged T7 RNA Polymerase for the Light Activation of Transcription and Gene Function in Pro- and Eukaryotic Cells

(2010) Chungjung Chou et al.   CHEMBIOCHEM

Protein Chemical Modification on Endogenous Amino Acids

(2010) Emmanuel Baslé et al.   CHEMISTRY & BIOLOGY

Protein N-Homocysteinylation Induces the Formation of Toxic Amyloid-Like Protofibrils

(2010) Paolo Paoli et al.   JOURNAL OF MOLECULAR BIOLOGY

Genetically Encoded Photocontrol of Protein Localization in Mammalian Cells

(2010) Arnaud Gautier et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

A genetically encoded photocaged Nε-methyl-l-lysine

(2010) Yane-Shih Wang et al.   Molecular BioSystems

Recent advances in the photochemical control of protein function

(2010) Chad W. Riggsbee et al.   TRENDS IN BIOTECHNOLOGY

Genetically encoding an aliphatic diazirine for protein photocrosslinking

(2010) Chungjung Chou et al.   Chemical Science

Light-Activated Cre Recombinase as a Tool for the Spatial and Temporal Control of Gene Function in Mammalian Cells

(2009) Wesleigh F. Edwards et al.   ACS Chemical Biology

Illuminating the Chemistry of Life: Design, Synthesis, and Applications of “Caged” and Related Photoresponsive Compounds

(2009) Hsien-Ming Lee et al.   ACS Chemical Biology

A Light-Activated DNA Polymerase

(2009) Chungjung Chou et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

A Facile System for Encoding Unnatural Amino Acids in Mammalian Cells

(2009) Peng R. Chen et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Principles and Applications of the Photochemical Control of Cellular Processes

(2009) Alexander Deiters   CHEMBIOCHEM

AutoDock4 and AutoDockTools4: Automated docking with selective receptor flexibility

(2009) Garrett M. Morris et al.   JOURNAL OF COMPUTATIONAL CHEMISTRY

Genetic Encoding and Labeling of Aliphatic Azides and Alkynes in Recombinant Proteinsviaa Pyrrolysyl-tRNA Synthetase/tRNACUAPair and Click Chemistry

(2009) Duy P. Nguyen et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Radical-free biology of oxidative stress

(2008) Dean P. Jones   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Efficient Site-Specific Labeling of Proteins via Cysteines

(2008) Younggyu Kim et al.   BIOCONJUGATE CHEMISTRY

Multistep Engineering of Pyrrolysyl-tRNA Synthetase to Genetically Encode Nɛ-(o-Azidobenzyloxycarbonyl) lysine for Site-Specific Protein Modification

(2008) Tatsuo Yanagisawa et al.   CHEMISTRY & BIOLOGY

Expanding the functional diversity of proteins through cysteine oxidation

(2008) Khalilah G Reddie et al.   CURRENT OPINION IN CHEMICAL BIOLOGY

Crystallographic Studies on Multiple Conformational States of Active-site Loops in Pyrrolysyl-tRNA Synthetase

(2008) Tatsuo Yanagisawa et al.   JOURNAL OF MOLECULAR BIOLOGY

Genetically encoding Nε-acetyllysine in recombinant proteins

(2008) Heinz Neumann et al.   Nature Chemical Biology

Structure-function studies on the active site of the coelenterazine-dependent luciferase fromRenilla

(2008) Jongchan Woo et al.   PROTEIN SCIENCE

Nonequilibrium thermodynamics of thiol/disulfide redox systems: A perspective on redox systems biology

(2007) Melissa Kemp et al.   FREE RADICAL BIOLOGY AND MEDICINE