Structural Insights into Incorporation of Norbornene Amino Acids for Click Modification of Proteins

Red-Light-Controlled Protein-RNA Crosslinking with a Genetically Encoded Furan

(2013) Moritz J. Schmidt et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Protein Organic Chemistry and Applications for Labeling and Engineering in Live-Cell Systems

(2013) Yousuke Takaoka et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

A novel crystal form of pyrrolysyl-tRNA synthetase reveals the pre- and post-aminoacyl-tRNA synthesis conformational states of the adenylate and aminoacyl moieties and an asparagine residue in the catalytic site

(2012) Tatsuo Yanagisawa et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Genetically Encoded Cyclopropene Directs Rapid, Photoclick-Chemistry-Mediated Protein Labeling in Mammalian Cells

(2012) Zhipeng Yu et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

A Genetically Encoded Norbornene Amino Acid for the Mild and Selective Modification of Proteins in a Copper-Free Click Reaction

(2012) Emine Kaya et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Amino Acids for Diels-Alder Reactions in Living Cells

(2012) Tilman Plass et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Genetic Encoding of a Bicyclo[6.1.0]nonyne-Charged Amino Acid Enables Fast Cellular Protein Imaging by Metal-Free Ligation

(2012) Annika Borrmann et al.   CHEMBIOCHEM

Genetic Encoding of Bicyclononynes and trans-Cyclooctenes for Site-Specific Protein Labeling in Vitro and in Live Mammalian Cells via Rapid Fluorogenic Diels–Alder Reactions

(2012) Kathrin Lang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

A Rationally Designed Pyrrolysyl-tRNA Synthetase Mutant with a Broad Substrate Spectrum

(2012) Yane-Shih Wang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Genetically encoded norbornene directs site-specific cellular protein labelling via a rapid bioorthogonal reaction

(2012) Kathrin Lang et al.   Nature Chemistry

REFMAC5 for the refinement of macromolecular crystal structures

(2011) Garib N. Murshudov et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Overview of theCCP4 suite and current developments

(2011) Martyn D. Winn et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Genetically Encoded Copper-Free Click Chemistry

(2011) Tilman Plass et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

A readily synthesized cyclic pyrrolysine analogue for site-specific protein “click” labeling

(2011) Ziyang Hao et al.   CHEMICAL COMMUNICATIONS

The pyrrolysine translational machinery as a genetic-code expansion tool

(2011) Tomasz Fekner et al.   CURRENT OPINION IN CHEMICAL BIOLOGY

The de novo engineering of pyrrolysyl-tRNA synthetase for genetic incorporation of l-phenylalanine and its derivatives

(2011) Yane-Shih Wang et al.   Molecular BioSystems

A genetically incorporated crosslinker reveals chaperone cooperation in acid resistance

(2011) Meng Zhang et al.   Nature Chemical Biology

Integration, scaling, space-group assignment and post-refinement

(2010) Wolfgang Kabsch   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Features and development ofCoot

(2010) P. Emsley et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

PHENIX: a comprehensive Python-based system for macromolecular structure solution

(2010) Paul D. Adams et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Adding New Chemistries to the Genetic Code

(2010) Chang C. Liu et al.   Annual Review of Biochemistry

A Pyrrolysine Analogue for Protein Click Chemistry

(2009) Tomasz Fekner et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

A Facile System for Encoding Unnatural Amino Acids in Mammalian Cells

(2009) Peng R. Chen et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Bioorthogonal Chemistry: Fishing for Selectivity in a Sea of Functionality

(2009) Ellen M. Sletten et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Synthesis of Threefold Glycosylated Proteins using Click Chemistry and Genetically Encoded Unnatural Amino Acids

(2009) Emine Kaya et al.   CHEMBIOCHEM

Genetic Encoding and Labeling of Aliphatic Azides and Alkynes in Recombinant Proteinsviaa Pyrrolysyl-tRNA Synthetase/tRNACUAPair and Click Chemistry

(2009) Duy P. Nguyen et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Adding l-lysine derivatives to the genetic code of mammalian cells with engineered pyrrolysyl-tRNA synthetases

(2008) Takahito Mukai et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Multistep Engineering of Pyrrolysyl-tRNA Synthetase to Genetically Encode Nɛ-(o-Azidobenzyloxycarbonyl) lysine for Site-Specific Protein Modification

(2008) Tatsuo Yanagisawa et al.   CHEMISTRY & BIOLOGY

Crystallographic Studies on Multiple Conformational States of Active-site Loops in Pyrrolysyl-tRNA Synthetase

(2008) Tatsuo Yanagisawa et al.   JOURNAL OF MOLECULAR BIOLOGY

Specificity of Pyrrolysyl-tRNA Synthetase for Pyrrolysine and Pyrrolysine Analogs

(2008) Wen-Tai Li et al.   JOURNAL OF MOLECULAR BIOLOGY

Geometric characteristics of hydrogen bonds involving sulfur atoms in proteins

(2008) Peng Zhou et al.   PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS