Sparsomycin-Linezolid Conjugates Can Promote Ribosomal Translocation

The ribosome as a molecular machine: the mechanism of tRNA–mRNA movement in translocation

(2011) Marina V. Rodnina et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

Structures of the Bacterial Ribosome in Classical and Hybrid States of tRNA Binding

(2011) J. A. Dunkle et al.   SCIENCE

Single Ribosome Dynamics and the Mechanism of Translation

(2010) Colin Echeverría Aitken et al.   Annual Review of Biophysics

Direct Observation of Distinct A/P Hybrid-State tRNAs in Translocating Ribosomes

(2010) John F. Flanagan et al.   STRUCTURE

Ribosomal Translocation: One Step Closer to the Molecular Mechanism

(2009) Shinichiro Shoji et al.   ACS Chemical Biology

The A–Z of bacterial translation inhibitors

(2009) Daniel N. Wilson   CRITICAL REVIEWS IN BIOCHEMISTRY AND MOLECULAR BIOLOGY

In Vitro Activities of the Rx-01 Oxazolidinones against Hospital and Community Pathogens

(2008) L. Lawrence et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

R -01, a New Family of Oxazolidinones That Overcome Ribosome-Based Linezolid Resistance

(2008) E. Skripkin et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Design at the atomic level: Design of biaryloxazolidinones as potent orally active antibiotics

(2008) Jiacheng Zhou et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Design at the atomic level: Generation of novel hybrid biaryloxazolidinones as promising new antibiotics

(2008) Jiacheng Zhou et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Crystal Structure of the Oxazolidinone Antibiotic Linezolid Bound to the 50S Ribosomal Subunit∥

(2008) Joseph A. Ippolito et al.   JOURNAL OF MEDICINAL CHEMISTRY

Preparation and evaluation of acylated tRNAs

(2008) Sarah E. Walker et al.   METHODS

Visualization of the Hybrid State of tRNA Binding Promoted by Spontaneous Ratcheting of the Ribosome

(2008) Xabier Agirrezabala et al.   MOLECULAR CELL

Role of hybrid tRNA-binding states in ribosomal translocation

(2008) S. E. Walker et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The oxazolidinone antibiotics perturb the ribosomal peptidyl-transferase center and effect tRNA positioning

(2008) D. N. Wilson et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Structure of ratcheted ribosomes with tRNAs in hybrid states

(2008) P. Julian et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Mechanics of Translocation: A Molecular “Spring-and-Ratchet” System

(2008) Stephen J. Moran et al.   STRUCTURE