A Comprehensive Panel of Turn-On Caspase Biosensors for Investigating Caspase Specificity and Caspase Activation Pathways

Protease Activation of Split Green Fluorescent Protein

(2010) Brian P. Callahan et al.   CHEMBIOCHEM

Noncovalent Tripeptidyl Benzyl- and Cyclohexyl-Amine Inhibitors of the Cysteine Protease Caspase-1

(2010) Reik Löser et al.   JOURNAL OF MEDICINAL CHEMISTRY

Inflammatory Stimuli Regulate Caspase Substrate Profiles

(2010) Nicholas J. Agard et al.   MOLECULAR & CELLULAR PROTEOMICS

Turning enzymes ON with small molecules

(2010) Julie A Zorn et al.   Nature Chemical Biology

Evaluation of recombinant caspase specificity by competitive substrates

(2009) Bistra Benkova et al.   ANALYTICAL BIOCHEMISTRY

An Improved Cell-Penetrating, Caspase-Activatable, Near-Infrared Fluorescent Peptide for Apoptosis Imaging

(2009) Dustin Maxwell et al.   BIOCONJUGATE CHEMISTRY

Ordering of caspases in cells undergoing apoptosis by the intrinsic pathway

(2009) S Inoue et al.   CELL DEATH AND DIFFERENTIATION

Designing Caspase-3 Sensors for Imaging of Apoptosis in Living Cells

(2009) Ning Chen et al.   CHEMISTRY-A EUROPEAN JOURNAL

PAC-1 Activates Procaspase-3 in Vitro through Relief of Zinc-Mediated Inhibition

(2009) Quinn P. Peterson et al.   JOURNAL OF MOLECULAR BIOLOGY

An Autoinhibited Coiled-Coil Design Strategy for Split-Protein Protease Sensors

(2009) Sujan S. Shekhawat et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Noninvasive optical imaging of apoptosis by caspase-targeted activity-based probes

(2009) Laura E Edgington et al.   NATURE MEDICINE

Small-Molecule Activators of a Proenzyme

(2009) D. W. Wolan et al.   SCIENCE

Novel Genetically Encoded Biosensors Using Firefly Luciferase

(2008) Frank Fan et al.   ACS Chemical Biology

Bright Ideas for Chemical Biology

(2008) Luke D. Lavis et al.   ACS Chemical Biology

Some commonly used caspase substrates and inhibitors lack the specificity required to monitor individual caspase activity

(2008) Natasha Ann Pereira et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Global Sequencing of Proteolytic Cleavage Sites in Apoptosis by Specific Labeling of Protein N Termini

(2008) Sami Mahrus et al.   CELL

Global Mapping of the Topography and Magnitude of Proteolytic Events in Apoptosis

(2008) Melissa M. Dix et al.   CELL

A General and Rapid Cell-Free Approach for the Interrogation of Protein−Protein, Protein−DNA, and Protein−RNA Interactions and their Antagonists Utilizing Split-Protein Reporters

(2008) Jason R. Porter et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Targeted Peptidecentric Proteomics Reveals Caspase-7 as a Substrate of the Caspase-1 Inflammasomes

(2008) Mohamed Lamkanfi et al.   MOLECULAR & CELLULAR PROTEOMICS

Quantitative Analysis of Pathways Controlling Extrinsic Apoptosis in Single Cells

(2008) John G. Albeck et al.   MOLECULAR CELL

Fluorescent protein FRET pairs for ratiometric imaging of dual biosensors

(2008) Hui-wang Ai et al.   NATURE METHODS

Executioner caspase-3 and caspase-7 are functionally distinct proteases

(2008) J. G. Walsh et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Apoptosis: controlled demolition at the cellular level

(2007) Rebecca C. Taylor et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY