The calcium release-activated calcium channel Orai1 represents a crucial component in hypertrophic compensation and the development of dilated cardiomyopathy

Successful TRPV1 antagonist treatment for cardiac hypertrophy and heart failure in mice

(2013) Jaime S. Horton et al.   Channels

Store-Independent Orai1/3 Channels Activated by Intracrine LeukotrieneC 4

(2013) José C. González-Cobos et al.   CIRCULATION RESEARCH

Pressure overload-induced cardiac remodeling and dysfunction in the absence of interleukin 6 in mice

(2012) N Chin Lai et al.   LABORATORY INVESTIGATION

STIM proteins: dynamic calcium signal transducers

(2012) Jonathan Soboloff et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Crystal Structure of the Calcium Release-Activated Calcium Channel Orai

(2012) X. Hou et al.   SCIENCE

Mice lacking functional TRPV1 are protected from pressure overload cardiac hypertrophy

(2011) Cadie L. Buckley et al.   Channels

Sensing cellular stress through STIM proteins

(2011) Jonathan Soboloff et al.   Nature Chemical Biology

Corin-deficient W-sh mice poorly tolerate increased cardiac afterload

(2011) Cadie L. Buckley et al.   REGULATORY PEPTIDES

Molecular mechanisms that control interstitial fibrosis in the pressure-overloaded heart

(2010) E. E. Creemers et al.   CARDIOVASCULAR RESEARCH

Protein Kinase C-induced Phosphorylation of Orai1 Regulates the Intracellular Ca2+Level via the Store-operated Ca2+Channel

(2010) Takumi Kawasaki et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Store-Operated Ca2+ Entry through ORAI1 Is Critical for T Cell-Mediated Autoimmunity and Allograft Rejection

(2010) C.-A. McCarl et al.   JOURNAL OF IMMUNOLOGY

Orai1 and Stim1 regulate normal and hypertrophic growth in cardiomyocytes

(2010) Mirko Voelkers et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Transforming growth factor (TGF)-β signaling in cardiac remodeling

(2010) Marcin Dobaczewski et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Small Animal Models of Heart Failure

(2009) Richard D. Patten et al.   Circulation-Heart Failure

ORAI1 deficiency and lack of store-operated Ca2+ entry cause immunodeficiency, myopathy, and ectodermal dysplasia

(2009) Christie-Ann McCarl et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

STIMulating store-operated Ca2+ entry

(2009) Michael D. Cahalan   NATURE CELL BIOLOGY

R93W mutation in Orai1 causes impaired calcium influx in platelets

(2008) W. Bergmeier et al.   BLOOD

Calcium signaling in lymphocytes

(2008) Masatsugu Oh-hora et al.   CURRENT OPINION IN IMMUNOLOGY

Molecular regulation of cardiac hypertrophy

(2008) Sean P. Barry et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY