Mesenchymal Stem Cells Restore Frataxin Expression and Increase Hydrogen Peroxide Scavenging Enzymes in Friedreich Ataxia Fibroblasts

Effects of Erythropoietin on Frataxin Levels and Mitochondrial Function in Friedreich Ataxia – a Dose–Response Trial

(2011) Wolfgang Nachbauer et al.   CEREBELLUM

Long intronic GAA repeats causing Friedreich ataxia impede transcription elongation

(2010) Tanel Punga et al.   EMBO Molecular Medicine

Human Mesenchymal Stem Cells Infiltrate the Spinal Cord, Reduce Demyelination, and Localize to White Matter Lesions in Experimental Autoimmune Encephalomyelitis

(2010) David Gordon et al.   JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY

Epoetin alfa increases frataxin production in Friedreich's ataxia without affecting hematocrit

(2010) Francesco Saccà et al.   MOVEMENT DISORDERS

Characterization of in vitro expanded bone marrow-derived mesenchymal stem cells from patients with multiple sclerosis

(2010) Elizabeth Mallam et al.   Multiple Sclerosis Journal

Fusion between human mesenchymal stem cells and rodent cerebellar Purkinje cells

(2010) K. Kemp et al.   NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY

Two New Pimelic Diphenylamide HDAC Inhibitors Induce Sustained Frataxin Upregulation in Cells from Friedreich's Ataxia Patients and in a Mouse Model

(2010) Myriam Rai et al.   PLoS One

PGC-1alpha Down-Regulation Affects the Antioxidant Response in Friedreich's Ataxia

(2010) Daniele Marmolino et al.   PLoS One

Inflammatory Cytokine Induced Regulation of Superoxide Dismutase 3 Expression by Human Mesenchymal Stem Cells

(2010) Kevin Kemp et al.   Stem Cell Reviews and Reports

Current and emerging treatment options in the management of Friedreich ataxia

(2010) Michelangelo Michelangelo Mancuso   Neuropsychiatric Disease and Treatment

Friedreich’s Ataxia: From the (GAA) n Repeat Mediated Silencing to New Promising Molecules for Therapy

(2009) Daniele Marmolino et al.   CEREBELLUM

Neuroprotective mesenchymal stem cells are endowed with a potent antioxidant effectin vivo

(2009) Cristina Lanza et al.   JOURNAL OF NEUROCHEMISTRY

Mesenchymal stem cell-secreted superoxide dismutase promotes cerebellar neuronal survival

(2009) Kevin Kemp et al.   JOURNAL OF NEUROCHEMISTRY

Impaired Nuclear Nrf2 Translocation Undermines the Oxidative Stress Response in Friedreich Ataxia

(2009) Vincent Paupe et al.   PLoS One

The First Cellular Models Based on Frataxin Missense Mutations That Reproduce Spontaneously the Defects Associated with Friedreich Ataxia

(2009) Nadège Calmels et al.   PLoS One

Human bone marrow-derived mesenchymal stem cells secrete brain-derived neurotrophic factor which promotes neuronal survival in vitro

(2009) Alastair Wilkins et al.   Stem Cell Research

Instability and chromatin structure of expanded trinucleotide repeats

(2009) Vincent Dion et al.   TRENDS IN GENETICS

Neuroprotection and Immunomodulation With Mesenchymal Stem Cells in Chronic Experimental Autoimmune Encephalomyelitis

(2008) Ibrahim Kassis et al.   ARCHIVES OF NEUROLOGY

Deferiprone targets aconitase: Implication for Friedreich's ataxia treatment

(2008) Sergio Goncalves et al.   BMC Neurology

Recombinant Human Erythropoietin Increases Frataxin Protein Expression Without Increasing mRNA Expression

(2008) Fabio Acquaviva et al.   CEREBELLUM

Iron-dependent regulation of frataxin expression: implications for treatment of Friedreich ataxia

(2008) K. Li et al.   HUMAN MOLECULAR GENETICS

Clinical Applications of Blood-Derived and Marrow-Derived Stem Cells for Nonmalignant Diseases

(2008) Richard K. Burt   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Protection against Hydrogen Peroxide-Mediated Cytotoxicity in Friedreich's Ataxia Fibroblasts Using Novel Iron Chelators of the 2-Pyridylcarboxaldehyde Isonicotinoyl Hydrazone Class

(2008) C. K. Lim et al.   MOLECULAR PHARMACOLOGY

Human mesenchymal stem cells abrogate experimental allergic encephalomyelitis after intraperitoneal injection, and with sparse CNS infiltration

(2008) David Gordon et al.   NEUROSCIENCE LETTERS

HDAC Inhibitors Correct Frataxin Deficiency in a Friedreich Ataxia Mouse Model

(2008) Myriam Rai et al.   PLoS One

Hydrogen peroxide scavenging rescues frataxin deficiency in a Drosophila model of Friedreich's ataxia

(2008) P. R. Anderson et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Drug Insight: antioxidant therapy in inherited ataxias

(2008) Massimo Pandolfo   Nature clinical practice. Neurology