Viral interference with innate immunity by preventing NF-κB activity

A238L Inhibits NF-ATc2, NF- B, and c-Jun Activation through a Novel Mechanism Involving Protein Kinase C- -Mediated Up-Regulation of the Amino-Terminal Transactivation Domain of p300

(2014) A. G. Granja et al.   JOURNAL OF IMMUNOLOGY

NFκB inhibitors: Strategies from poxviruses

(2011) Mohamed Ragaa Mohamed et al.   CELL CYCLE

Regulation of the Antimicrobial Response by NLR Proteins

(2011) Eran Elinav et al.   IMMUNITY

Pathogen Recognition by the Innate Immune System

(2011) Himanshu Kumar et al.   INTERNATIONAL REVIEWS OF IMMUNOLOGY

Modulation of NF-κB signalling by microbial pathogens

(2011) Masmudur M. Rahman et al.   NATURE REVIEWS MICROBIOLOGY

Peroxisomes Are Signaling Platforms for Antiviral Innate Immunity

(2010) Evelyn Dixit et al.   CELL

Non-canonical NF-κB signaling pathway

(2010) Shao-Cong Sun   CELL RESEARCH

Control of infection by pyroptosis and autophagy: role of TLR and NLR

(2010) Karina R. Bortoluci et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Sensing and Signaling in Antiviral Innate Immunity

(2010) Luke A.J. O'Neill et al.   CURRENT BIOLOGY

Recognition of viruses by cytoplasmic sensors

(2010) Courtney Wilkins et al.   CURRENT OPINION IN IMMUNOLOGY

Disruption of NF- B signalling by ancient microbial molecules: novel therapies of the future?

(2010) F. Yan et al.   GUT

Viral Inhibitory Peptide of TLR4, a Peptide Derived from Vaccinia Protein A46, Specifically Inhibits TLR4 by Directly Targeting MyD88 Adaptor-Like and TRIF-Related Adaptor Molecule

(2010) T. Lysakova-Devine et al.   JOURNAL OF IMMUNOLOGY

Vaccinia Virus Virulence Factor N1L is a Novel Promising Target for Antiviral Therapeutic Intervention

(2010) Anton V. Cheltsov et al.   JOURNAL OF MEDICINAL CHEMISTRY

Herpes Simplex Virus Immediate-Early ICP0 Protein Inhibits Toll-Like Receptor 2-Dependent Inflammatory Responses and NF-κB Signaling

(2010) Allison L. van Lint et al.   JOURNAL OF VIROLOGY

The Battle between Virus and Host: Modulation of Toll-Like Receptor Signaling Pathways by Virus Infection

(2010) Shin-ichi Yokota et al.   MEDIATORS OF INFLAMMATION

Negative Feedback in Noncanonical NF- B Signaling Modulates NIK Stability Through IKK -Mediated Phosphorylation

(2010) B. Razani et al.   Science Signaling

MNF, an ankyrin repeat protein of myxoma virus, is part of a native cellular SCF complex during viral infection

(2010) Sophie Blanié et al.   Virology Journal

Toll-like Receptor and RIG-1-like Receptor Signaling

(2009) Taro Kawai et al.   Annals of the New York Academy of Sciences

Inhibition of TNF-α-induced Activation of NF-κB by Hantavirus Nucleocapsid Proteins

(2009) Shannon L. Taylor et al.   Annals of the New York Academy of Sciences

Regulation and Function of NF-κB Transcription Factors in the Immune System

(2009) Sivakumar Vallabhapurapu et al.   Annual Review of Immunology

Toll-like receptors and innate immunity

(2009) Himanshu Kumar et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Evasion and disruption of innate immune signalling by hepatitis C and West Nile viruses

(2009) Mehul S. Suthar et al.   CELLULAR MICROBIOLOGY

Roles of NF-κB in health and disease: mechanisms and therapeutic potential

(2009) Ee Tsin Wong et al.   CLINICAL SCIENCE

The roles of TLRs, RLRs and NLRs in pathogen recognition

(2009) T. Kawai et al.   INTERNATIONAL IMMUNOLOGY

The Hepatitis C Virus Non-structural NS5A Protein Impairs Both the Innate and Adaptive Hepatic Immune Responsein Vivo

(2009) Malte Kriegs et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

NF-κB regulation: the nuclear response

(2009) Arun K. Mankan et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Rotavirus Antagonizes Cellular Antiviral Responses by Inhibiting the Nuclear Accumulation of STAT1, STAT2, and NF- B

(2009) G. Holloway et al.   JOURNAL OF VIROLOGY

Poxvirus MC160 Protein Utilizes Multiple Mechanisms To Inhibit NF- B Activation Mediated via Components of the Tumor Necrosis Factor Receptor 1 Signal Transduction Pathway

(2009) D. B. Nichols et al.   JOURNAL OF VIROLOGY

Cowpox Virus Expresses a Novel Ankyrin Repeat NF- B Inhibitor That Controls Inflammatory Cell Influx into Virus-Infected Tissues and Is Critical for Virus Pathogenesis

(2009) M. R. Mohamed et al.   JOURNAL OF VIROLOGY

Poxvirus Host Range Protein CP77 Contains an F-Box-Like Domain That Is Necessary To Suppress NF- B Activation by Tumor Necrosis Factor Alpha but Is Independent of Its Host Range Function

(2009) S.-J. Chang et al.   JOURNAL OF VIROLOGY

PKC Phosphorylation of TRAF2 Mediates IKKα/β Recruitment and K63-Linked Polyubiquitination

(2009) Shitao Li et al.   MOLECULAR CELL

AIM2 activates the inflammasome and cell death in response to cytoplasmic DNA

(2009) Teresa Fernandes-Alnemri et al.   NATURE

AIM2 recognizes cytosolic dsDNA and forms a caspase-1-activating inflammasome with ASC

(2009) Veit Hornung et al.   NATURE

Proteomic screening of variola virus reveals a unique NF- B inhibitor that is highly conserved among pathogenic orthopoxviruses

(2009) M. R. Mohamed et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The innate immune response to DNA

(2009) Akosua Vilaysane et al.   SEMINARS IN IMMUNOLOGY

Walleye dermal sarcoma virus rv-cyclin inhibits NF-κB-dependent transcription

(2009) Sandra L. Quackenbush et al.   VIROLOGY

Rotavirus NSP1 Inhibits NFκB Activation by Inducing Proteasome-Dependent Degradation of β-TrCP: A Novel Mechanism of IFN Antagonism

(2009) Joel W. Graff et al.   PLoS Pathogens

Co-Regulation of NF-κB and Inflammasome-Mediated Inflammatory Responses by Myxoma Virus Pyrin Domain-Containing Protein M013

(2009) Masmudur M. Rahman et al.   PLoS Pathogens

Ubiquitin and ubiquitin-like specific proteases targeted by infectious pathogens: Emerging patterns and molecular principles

(2008) Mariola J. Edelmann et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

HSV-1 ICP27 suppresses NF-κB activity by stabilizing IκBα

(2008) Jin Chul Kim et al.   FEBS LETTERS

The NLR Gene Family: A Standard Nomenclature

(2008) Jenny P.-Y. Ting et al.   IMMUNITY

Autophagy and pattern recognition receptors in innate immunity

(2008) Monica Delgado et al.   IMMUNOLOGICAL REVIEWS

Interferons: Signaling, antiviral and viral evasion

(2008) Cláudio A. Bonjardim et al.   IMMUNOLOGY LETTERS

Co-evolution and exploitation of host cell signaling pathways by bacterial pathogens

(2008) Stephanie R. Shames et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

CD95 Stimulation Results in the Formation of a Novel Death Effector Domain Protein-containing Complex

(2008) Inna N. Lavrik et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Vaccinia virus lacking the Bcl-2-like protein N1 induces a stronger natural killer cell response to infection

(2008) N. Jacobs et al.   JOURNAL OF GENERAL VIROLOGY

Hantaan Virus Nucleocapsid Protein Binds to Importin   Proteins and Inhibits Tumor Necrosis Factor Alpha-Induced Activation of Nuclear Factor Kappa B

(2008) S. L. Taylor et al.   JOURNAL OF VIROLOGY

West Nile Virus Nonstructural Protein 1 Inhibits TLR3 Signal Transduction

(2008) J. R. Wilson et al.   JOURNAL OF VIROLOGY

IKK/NF-κB signaling in intestinal epithelial cells controls immune homeostasis in the gut

(2008) M Pasparakis   Mucosal Immunology

Nonredundant and complementary functions of TRAF2 and TRAF3 in a ubiquitination cascade that activates NIK-dependent alternative NF-κB signaling

(2008) Sivakumar Vallabhapurapu et al.   NATURE IMMUNOLOGY

Noncanonical NF-κB activation requires coordinated assembly of a regulatory complex of the adaptors cIAP1, cIAP2, TRAF2 and TRAF3 and the kinase NIK

(2008) Brian J Zarnegar et al.   NATURE IMMUNOLOGY

Robust Intrapulmonary CD8 T Cell Responses and Protection with an Attenuated N1L Deleted Vaccinia Virus

(2008) Anuja Mathew et al.   PLoS One

Inhibition of IκB Kinase by Vaccinia Virus Virulence Factor B14

(2008) Ron A.-J. Chen et al.   PLoS Pathogens

Poxvirus ankyrin repeat proteins are a unique class of F-box proteins that associate with cellular SCF1 ubiquitin ligase complexes

(2008) S. Sonnberg et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Vaccinia Virus Proteins A52 and B14 Share a Bcl-2–Like Fold but Have Evolved to Inhibit NF-κB rather than Apoptosis

(2008) Stephen C. Graham et al.   PLoS Pathogens

The interplay between viruses and innate immune signaling: Recent insights and therapeutic opportunities

(2007) Leonie Unterholzner et al.   BIOCHEMICAL PHARMACOLOGY