Non-phosphorylated FTY720 Induces Apoptosis of Human Microglia by Activating SREBP2
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Title
Non-phosphorylated FTY720 Induces Apoptosis of Human Microglia by Activating SREBP2
Authors
Keywords
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Journal
CELLULAR AND MOLECULAR NEUROBIOLOGY
Volume 31, Issue 7, Pages 1009-1020
Publisher
Springer Nature
Online
2011-04-25
DOI
10.1007/s10571-011-9698-x
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- (2010) Ryuichiro Sato ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS
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- Sphingosine and FTY720 directly bind pro-survival 14-3-3 proteins to regulate their function
- (2010) Joanna M. Woodcock et al. CELLULAR SIGNALLING
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- (2010) Tomas Blom et al. CIRCULATION RESEARCH
- FTY720 Shows Promising In vitro and In vivo Preclinical Activity by Downmodulating Cyclin D1 and Phospho-Akt in Mantle Cell Lymphoma
- (2010) Q. Liu et al. CLINICAL CANCER RESEARCH
- CYP4F Enzymes Are Responsible for the Elimination of Fingolimod (FTY720), a Novel Treatment of Relapsing Multiple Sclerosis
- (2010) Y. Jin et al. DRUG METABOLISM AND DISPOSITION
- The Sphingosine 1-Phosphate Transporter, SPNS2, Functions as a Transporter of the Phosphorylated Form of the Immunomodulating Agent FTY720
- (2010) Yu Hisano et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Differential responses of human microglia and blood-derived myeloid cells to FTY720
- (2010) Bryce A. Durafourt et al. JOURNAL OF NEUROIMMUNOLOGY
- Fingolimod (FTY720): discovery and development of an oral drug to treat multiple sclerosis
- (2010) Volker Brinkmann et al. NATURE REVIEWS DRUG DISCOVERY
- Human Microglia Transplanted in Rat Focal Ischemia Brain Induce Neuroprotection and Behavioral Improvement
- (2010) Dashdemberel Narantuya et al. PLoS One
- FTY720 (fingolimod) efficacy in an animal model of multiple sclerosis requires astrocyte sphingosine 1-phosphate receptor 1 (S1P1) modulation
- (2010) J. W. Choi et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Sphingosine-1-phosphate and immune regulation: trafficking and beyond
- (2010) Hongbo Chi TRENDS IN PHARMACOLOGICAL SCIENCES
- Human caspase 7 is positively controlled by SREBP-1 and SREBP-2
- (2009) Laure Gibot et al. BIOCHEMICAL JOURNAL
- Down-regulation of S1P1Receptor Surface Expression by Protein Kinase C Inhibition
- (2009) Sven-Christian Sensken et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- FTY720 Inhibits Ceramide Synthases and Up-regulates Dihydrosphingosine 1-Phosphate Formation in Human Lung Endothelial Cells
- (2009) Evgeny V. Berdyshev et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Persistent signaling induced by FTY720-phosphate is mediated by internalized S1P1 receptors
- (2009) Florian Mullershausen et al. Nature Chemical Biology
- Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources
- (2009) Da Wei Huang et al. Nature Protocols
- Effects of Phosphorylation of Immunomodulatory Agent FTY720 (Fingolimod) on Antiproliferative Activity against Breast and Colon Cancer Cells
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- (2007) Kumlesh K. Dev et al. PHARMACOLOGY & THERAPEUTICS
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