Physical activity and the endocannabinoid system: an overview

N-Acetylcysteine’s Attenuation of Fatigue after Repeated Bouts of Intermittent Exercise: Practical Implications for Tournament Situations

(2016) James N. Cobley et al.   INTERNATIONAL JOURNAL OF SPORT NUTRITION AND EXERCISE METABOLISM

Selection for increased voluntary wheel-running affects behavior and brain monoamines in mice

(2013) R.Parrish Waters et al.   BRAIN RESEARCH

The Endocannabinoid System in Energy Homeostasis and the Etiopathology of Metabolic Disorders

(2013) Cristoforo Silvestri et al.   Cell Metabolism

Activation of type-2 cannabinoid receptor inhibits neuroprotective and antiinflammatory actions of glucocorticoid receptor α: when one is better than two

(2013) Elisa Bisicchia et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Retrograde cPLA2α/Arachidonic Acid/2-AG Signaling Is Essential for Cerebellar Depolarization-Induced Suppression of Excitation and Long-Term Potentiation

(2013) Li-Da Su et al.   CEREBELLUM

GPR55 and its Interaction with Membrane Lipids: Comparison with Other Endocannabinoid-Binding Receptors

(2013) V. Gasperi et al.   CURRENT MEDICINAL CHEMISTRY

Metabolism of endocannabinoids and relatedN-acylethanolamines: Canonical and alternative pathways

(2013) Natsuo Ueda et al.   FEBS Journal

The Fatty Acid Amide Hydrolase in Lymphocytes from Sedentary and Active Subjects

(2013) VALERIA GASPERI et al.   MEDICINE AND SCIENCE IN SPORTS AND EXERCISE

Palmitoylethanolamide and stearoylethanolamide levels in the interstitium of the trapezius muscle of women with chronic widespread pain and chronic neck-shoulder pain correlate with pain intensity and sensitivity

(2013) Nazdar Ghafouri et al.   PAIN

Type-1 (CB1) Cannabinoid Receptor Promotes Neuronal Differentiation and Maturation of Neural Stem Cells

(2013) Claudia Compagnucci et al.   PLoS One

Obesity-driven synaptic remodeling affects endocannabinoid control of orexinergic neurons

(2013) L. Cristino et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Fat to treat fat: Emerging relationship between dietary PUFA, endocannabinoids, and obesity

(2013) Jeffrey Kim et al.   PROSTAGLANDINS & OTHER LIPID MEDIATORS

The inhibition of 2-arachidonoyl-glycerol (2-AG) biosynthesis, rather than enhancing striatal damage, protects striatal neurons from malonate-induced death: a potential role of cyclooxygenase-2-dependent metabolism of 2-AG

(2013) S Valdeolivas et al.   Cell Death & Disease

Ventral Tegmental Area Cannabinoid Type-1 Receptors Control Voluntary Exercise Performance

(2012) Sarah Dubreucq et al.   BIOLOGICAL PSYCHIATRY

Uncoupling of sarcoplasmic reticulum Ca2+-ATPase by N-arachidonoyl dopamine. Members of the endocannabinoid family as thermogenic drugs

(2012) YA Mahmmoud et al.   BRITISH JOURNAL OF PHARMACOLOGY

Depression and treatment response: dynamic interplay of signaling pathways and altered neural processes

(2012) Vanja Duric et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Opioid Receptor Blockade Prevents Exercise-Associated Autonomic Failure in Humans

(2012) S. Milman et al.   DIABETES

Role of resting metabolic rate and energy expenditure in hunger and appetite control: a new formulation

(2012) J. E. Blundell et al.   Disease Models & Mechanisms

Exercise-induced endocannabinoid signaling is modulated by intensity

(2012) David A. Raichlen et al.   EUROPEAN JOURNAL OF APPLIED PHYSIOLOGY

Does the difference between physically active and couch potato lie in the dopamine system?

(2012) Amy M. Knab et al.   International Journal of Biological Sciences

Evidence for Bidirectional Endocannabinoid Transport across Cell Membranes

(2012) Andrea Chicca et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Omega-3 PUFA ethanolamides DHEA and EPEA induce autophagy through PPARγ activation in MCF-7 breast cancer cells

(2012) Daniela Rovito et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Wired to run: exercise-induced endocannabinoid signaling in humans and cursorial mammals with implications for the 'runner's high'

(2012) D. A. Raichlen et al.   JOURNAL OF EXPERIMENTAL BIOLOGY

How well do muscle biomechanics predict whole-animal locomotor performance? The role of Ca2+ handling

(2012) F. Seebacher et al.   JOURNAL OF EXPERIMENTAL BIOLOGY

Gating the Polarity of Endocannabinoid-Mediated Synaptic Plasticity by Nitric Oxide in the Spinal Locomotor Network

(2012) J. Song et al.   JOURNAL OF NEUROSCIENCE

The CB1 Cannabinoid Receptor Drives Corticospinal Motor Neuron Differentiation through the Ctip2/Satb2 Transcriptional Regulation Axis

(2012) J. Diaz-Alonso et al.   JOURNAL OF NEUROSCIENCE

Involvement of the L-arginine/nitric oxide/cyclic guanosine monophosphate pathway in peripheral antinociception induced by N-palmitoyl-ethanolamine in rats

(2012) Thiago R.L. Romero et al.   JOURNAL OF NEUROSCIENCE RESEARCH

Regulation and limitations to fatty acid oxidation during exercise

(2012) Jacob Jeppesen et al.   JOURNAL OF PHYSIOLOGY-LONDON

Neural precursor cells induce cell death of high-grade astrocytomas through stimulation of TRPV1

(2012) Kristin Stock et al.   NATURE MEDICINE

Effects of voluntary running on plasma levels of neurotrophins, hippocampal cell proliferation and learning and memory in stressed rats

(2012) S.-Y. Yau et al.   NEUROSCIENCE

Sex differences in cannabinoid receptor-1 (CB1) pharmacology in mice selectively bred for high voluntary wheel-running behavior

(2012) Brooke K. Keeney et al.   PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR

Antidepressant-like effects of Δ9-tetrahydrocannabinol and rimonabant in the olfactory bulbectomised rat model of depression

(2012) Maha M. ElBatsh et al.   PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR

Anandamide uptake explained?

(2012) Christopher J. Fowler   TRENDS IN PHARMACOLOGICAL SCIENCES

Muscle-to-organ cross talk mediated by myokines

(2012) Line Pedersen et al.   Adipocyte

Chronic Inflammatory Disorders and Their Redox Control: From Molecular Mechanisms to Therapeutic Opportunities

(2011) Valerio Chiurchiù et al.   ANTIOXIDANTS & REDOX SIGNALING

Exercise as a therapeutic modality in patients with idiopathic inflammatory myopathies

(2011) Helene Alexanderson et al.   CURRENT OPINION IN RHEUMATOLOGY

The L- -Lysophosphatidylinositol/GPR55 System and Its Potential Role in Human Obesity

(2011) J. M. Moreno-Navarrete et al.   DIABETES

Effects of exercise stress on the endocannabinoid system in humans under field conditions

(2011) M. Feuerecker et al.   EUROPEAN JOURNAL OF APPLIED PHYSIOLOGY

The effect of 4-week training period on plasma neuropeptide Y, leptin and ghrelin responses in male rowers

(2011) R. Rämson et al.   EUROPEAN JOURNAL OF APPLIED PHYSIOLOGY

Exercise for the Treatment of Depression and Anxiety

(2011) Peter J. Carek et al.   INTERNATIONAL JOURNAL OF PSYCHIATRY IN MEDICINE

Exercise, brain, and cognition across the life span

(2011) Michelle W. Voss et al.   JOURNAL OF APPLIED PHYSIOLOGY

Variation in expression of calcium-handling proteins is associated with inter-individual differences in mechanical performance of rat (Rattus norvegicus) skeletal muscle

(2011) R. S. James et al.   JOURNAL OF EXPERIMENTAL BIOLOGY

The BASES Expert Statement on Exercise, Immunity, and Infection

(2011) Michael Gleeson et al.   JOURNAL OF SPORTS SCIENCES

Adipose tissue endocannabinoid system gene expression: depot differences and effects of diet and exercise

(2011) Tongjian You et al.   Lipids in Health and Disease

Effect of Exercise Intensity on the Cytokine Response to an Acute Bout of Running

(2011) JONATHAN PAUL RICHARD SCOTT et al.   MEDICINE AND SCIENCE IN SPORTS AND EXERCISE

Muscular Interleukin-6 and Its Role as an Energy Sensor

(2011) BENTE KLARLUND PEDERSEN   MEDICINE AND SCIENCE IN SPORTS AND EXERCISE

Pharmacological elevation of anandamide impairs short-term memory by altering the neurophysiology in the hippocampus

(2011) Anushka V. Goonawardena et al.   NEUROPHARMACOLOGY

Cannabinoids Prevent the Development of Behavioral and Endocrine Alterations in a Rat Model of Intense Stress

(2011) Eti Ganon-Elazar et al.   NEUROPSYCHOPHARMACOLOGY

Nitric oxide: Is it the cause of muscle soreness?

(2011) Zsolt Radak et al.   NITRIC OXIDE-BIOLOGY AND CHEMISTRY

Aerobic Exercise Training Reduces Cannabis Craving and Use in Non-Treatment Seeking Cannabis-Dependent Adults

(2011) Maciej S. Buchowski et al.   PLoS One

Time-Course of Changes in Inflammatory Response after Whole-Body Cryotherapy Multi Exposures following Severe Exercise

(2011) Hervé Pournot et al.   PLoS One

Exercise in Obesity, Metabolic Syndrome, and Diabetes

(2011) Tim Church   PROGRESS IN CARDIOVASCULAR DISEASES

Intense exercise increases circulating endocannabinoid and BDNF levels in humans—Possible implications for reward and depression

(2011) E. Heyman et al.   PSYCHONEUROENDOCRINOLOGY

Effect of exercise training intensity on murine T-regulatory cells and vaccination response

(2011) J. Wang et al.   SCANDINAVIAN JOURNAL OF MEDICINE & SCIENCE IN SPORTS

Endocannabinoid Hydrolysis Generates Brain Prostaglandins That Promote Neuroinflammation

(2011) D. K. Nomura et al.   SCIENCE

The Endocannabinoid System and Its Relevance for Nutrition

(2010) Mauro Maccarrone et al.   Annual Review of Nutrition

Effects of 2-AG on the reinforcing properties of wheel activity in obese and lean Zucker rats

(2010) Shilo L. Smith et al.   BEHAVIOURAL PHARMACOLOGY

Cannabinoid receptor-dependent and -independent anti-proliferative effects of omega-3 ethanolamides in androgen receptor-positive and -negative prostate cancer cell lines

(2010) Iain Brown et al.   CARCINOGENESIS

CB1 Cannabinoid Receptors and their Associated Proteins

(2010) Allyn Howlett et al.   CURRENT MEDICINAL CHEMISTRY

Endocannabinoids as Regulators of Transient Receptor Potential (TRP)Channels: a Further Opportunity to Develop New Endocannabinoid-Based Therapeutic Drugs

(2010) V. Marzo et al.   CURRENT MEDICINAL CHEMISTRY

Cannabinoid CB2 Receptors in Health and Disease

(2010) K. Patel et al.   CURRENT MEDICINAL CHEMISTRY

Cannabinoid Receptor Stimulation Impairs Mitochondrial Biogenesis in Mouse White Adipose Tissue, Muscle, and Liver: The Role of eNOS, p38 MAPK, and AMPK Pathways

(2010) L. Tedesco et al.   DIABETES

CB1 Antagonism Exerts Specific Molecular Effects on Visceral and Subcutaneous Fat and Reverses Liver Steatosis in Diet-Induced Obese Mice

(2010) T. Jourdan et al.   DIABETES

Effects of in vitro antagonism of endocannabinoid-1 receptors on the glucose transport system in normal and insulin-resistant rat skeletal muscle

(2010) K. A. Lindborg et al.   DIABETES OBESITY & METABOLISM

Deficiency of CB2 cannabinoid receptor in mice improves insulin sensitivity but increases food intake and obesity with age

(2010) J. Agudo et al.   DIABETOLOGIA

The effects of anandamide transport inhibitor AM404 on voltage-dependent calcium channels

(2010) Alp Alptekin et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Aging, Persistent Viral Infections, and Immunosenescence

(2010) Richard J. Simpson   EXERCISE AND SPORT SCIENCES REVIEWS

The endocannabinoid system and migraine

(2010) Rosaria Greco et al.   EXPERIMENTAL NEUROLOGY

CB1 receptor deficiency decreases wheel-running activity: Consequences on emotional behaviours and hippocampal neurogenesis

(2010) Sarah Dubreucq et al.   EXPERIMENTAL NEUROLOGY

Fatty acid amide hydrolase is a key regulator of endocannabinoid-induced myocardial tissue injury

(2010) Partha Mukhopadhyay et al.   FREE RADICAL BIOLOGY AND MEDICINE

Characterization of mice lacking candidate N-acyl ethanolamine biosynthetic enzymes provides evidence for multiple pathways that contribute to endocannabinoid production in vivo

(2010) Gabriel M. Simon et al.   Molecular BioSystems

The serine hydrolase ABHD6 controls the accumulation and efficacy of 2-AG at cannabinoid receptors

(2010) William R Marrs et al.   NATURE NEUROSCIENCE

Physical exercise in adolescence changes CB1 cannabinoid receptor expression in the rat brain

(2010) Sérgio Gomes da Silva et al.   NEUROCHEMISTRY INTERNATIONAL

International Union of Basic and Clinical Pharmacology. LXXIX. Cannabinoid Receptors and Their Ligands: Beyond CB1 and CB2

(2010) R. G. Pertwee et al.   PHARMACOLOGICAL REVIEWS

Anandamide Suppresses Proliferation and Cytokine Release from Primary Human T-Lymphocytes Mainly via CB2 Receptors

(2010) Maria Teresa Cencioni et al.   PLoS One

Intracellular trafficking of anandamide: new concepts for signaling

(2010) Mauro Maccarrone et al.   TRENDS IN BIOCHEMICAL SCIENCES

An introduction to the endocannabinoid system: from the early to the latest concepts

(2009) Luciano De Petrocellis et al.   BEST PRACTICE & RESEARCH CLINICAL ENDOCRINOLOGY & METABOLISM

Regulation of MAP Kinase-Directed Mitogenic and Protein Kinase B-Mediated Signaling by Cannabinoid Receptor Type 1 in Skeletal Muscle Cells

(2009) C. Lipina et al.   DIABETES

Role of insulin as a negative regulator of plasma endocannabinoid levels in obese and nonobese subjects

(2009) Vincenzo Di Marzo et al.   EUROPEAN JOURNAL OF ENDOCRINOLOGY

Kinetic Evidence for Unique Regulation of GLUT4 Trafficking by Insulin and AMP-activated Protein Kinase Activators in L6 Myotubes

(2009) Daniel J. Fazakerley et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Effects of Cannabinoids on Caffeine Contractures in Slow and Fast Skeletal Muscle Fibers of the Frog

(2009) Miguel Huerta et al.   JOURNAL OF MEMBRANE BIOLOGY

Selective CB2 Receptor Agonism Protects Central Neurons from Remote Axotomy-Induced Apoptosis through the PI3K/Akt Pathway

(2009) M. T. Viscomi et al.   JOURNAL OF NEUROSCIENCE

The diseasome of physical inactivity - and the role of myokines in muscle-fat cross talk

(2009) Bente K. Pedersen   JOURNAL OF PHYSIOLOGY-LONDON

Fatty acid amide hydrolase (FAAH) inhibition enhances memory acquisition through activation of PPAR-  nuclear receptors

(2009) C. Mazzola et al.   LEARNING & MEMORY

Voluntary Exercise and Sucrose Consumption Enhance Cannabinoid CB1 Receptor Sensitivity in the Striatum

(2009) Valentina De Chiara et al.   NEUROPSYCHOPHARMACOLOGY

Endocannabinoids and immune regulation☆

(2009) Rupal Pandey et al.   PHARMACOLOGICAL RESEARCH

The transcriptional coactivator PGC-1α mediates exercise-induced angiogenesis in skeletal muscle

(2009) Jessica Chinsomboon et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The future of endocannabinoid-oriented clinical research after CB1 antagonists

(2009) Bernard Le Foll et al.   PSYCHOPHARMACOLOGY

The enigmatic pharmacology of GPR55

(2009) Ruth A. Ross   TRENDS IN PHARMACOLOGICAL SCIENCES

Influence of resistance and aerobic exercise on hunger, circulating levels of acylated ghrelin, and peptide YY in healthy males

(2008) David R. Broom et al.   AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY

Differential response to a selective cannabinoid receptor antagonist (SR141716: rimonabant) in female mice from lines selectively bred for high voluntary wheel-running behaviour

(2008) Brooke K. Keeney et al.   BEHAVIOURAL PHARMACOLOGY

Behavioral and temperature effects of delta 9-tetrahydrocannabinol in human-relevant doses in rats

(2008) Michael S. Smirnov et al.   BRAIN RESEARCH

The endocannabinoid system in brain reward processes

(2008) M Solinas et al.   BRITISH JOURNAL OF PHARMACOLOGY

Review on leptin and adiponectin responses and adaptations to acute and chronic exercise

(2008) A. Bouassida et al.   BRITISH JOURNAL OF SPORTS MEDICINE

Evidence for the intracellular accumulation of anandamide in adiposomes

(2008) S. Oddi et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Peripheral, but Not Central, CB1 Antagonism Provides Food Intake-Independent Metabolic Benefits in Diet-Induced Obese Rats

(2008) R. Nogueiras et al.   DIABETES

Changes in plasma endocannabinoid levels in viscerally obese men following a 1 year lifestyle modification programme and waist circumference reduction: associations with changes in metabolic risk factors

(2008) V. Di Marzo et al.   DIABETOLOGIA

Cannabinoid type 1 receptors in human skeletal muscle cells participate in the negative crosstalk between fat and muscle

(2008) K. Eckardt et al.   DIABETOLOGIA

Aerobic exercise decreases the positive-reinforcing effects of cocaine

(2008) Mark A. Smith et al.   DRUG AND ALCOHOL DEPENDENCE

Shifts in macrophage phenotypes and macrophage competition for arginine metabolism affect the severity of muscle pathology in muscular dystrophy

(2008) S. A. Villalta et al.   HUMAN MOLECULAR GENETICS

Effects of Different Levels of Exercise Volume on Endothelium-Dependent Vasodilation: Roles of Nitric Oxide Synthase and Heme Oxygenase

(2008) Meng-Wei Sun et al.   HYPERTENSION RESEARCH

A comparative study on cannabidiol-induced apoptosis in murine thymocytes and EL-4 thymoma cells

(2008) Chi-Ya Lee et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Hepatic CB1 receptor is required for development of diet-induced steatosis, dyslipidemia, and insulin and leptin resistance in mice

(2008) Douglas Osei-Hyiaman et al.   JOURNAL OF CLINICAL INVESTIGATION

Exercise training-induced lowering of inflammatory (CD14+CD16+) monocytes: a role in the anti-inflammatory influence of exercise?

(2008) Kyle L. Timmerman et al.   JOURNAL OF LEUKOCYTE BIOLOGY

BDNF impairment in the hippocampus is related to enhanced despair behavior in CB1knockout mice

(2008) Ester Aso et al.   JOURNAL OF NEUROCHEMISTRY

Repeated bouts of aerobic exercise lead to reductions in skeletal muscle free radical generation and nuclear factor κB activation

(2008) Susan V. Brooks et al.   JOURNAL OF PHYSIOLOGY-LONDON

The Cannabinoid CB1 Receptor Antagonist Rimonabant Stimulates 2-Deoxyglucose Uptake in Skeletal Muscle Cells by Regulating the Expression of Phosphatidylinositol-3-kinase

(2008) I. Esposito et al.   MOLECULAR PHARMACOLOGY

Central Mechanisms of HPA Axis Regulation by Voluntary Exercise

(2008) Alexis M. Stranahan et al.   NEUROMOLECULAR MEDICINE

Pharmacological enhancement of the endocannabinoid system in the nucleus accumbens shell stimulates food intake and increases c-Fos expression in the hypothalamus

(2007) E Soria-Gómez et al.   BRITISH JOURNAL OF PHARMACOLOGY

Antidepressant-like behavioral effects of impaired cannabinoid receptor type 1 signaling coincide with exaggerated corticosterone secretion in mice

(2007) Michel A. Steiner et al.   PSYCHONEUROENDOCRINOLOGY