Iron transport across the blood–brain barrier: development, neurovascular regulation and cerebral amyloid angiopathy
Published 2014 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Iron transport across the blood–brain barrier: development, neurovascular regulation and cerebral amyloid angiopathy
Authors
Keywords
-
Journal
CELLULAR AND MOLECULAR LIFE SCIENCES
Volume 72, Issue 4, Pages 709-727
Publisher
Springer Nature
Online
2014-10-29
DOI
10.1007/s00018-014-1771-4
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- sAPP modulates iron efflux from brain microvascular endothelial cells by stabilizing the ferrous iron exporter ferroportin
- (2014) R. C. McCarthy et al. EMBO REPORTS
- Ferrous iron formation following the co-aggregation of ferric iron and the Alzheimer's disease peptide -amyloid (1-42)
- (2014) J. Everett et al. Journal of the Royal Society Interface
- Glial Cell Ceruloplasmin and Hepcidin Differentially Regulate Iron Efflux from Brain Microvascular Endothelial Cells
- (2014) Ryan C. McCarthy et al. PLoS One
- Functional properties of human ferroportin, a cellular iron exporter reactive also with cobalt and zinc
- (2013) Colin J. Mitchell et al. AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY
- Iron uptake in quiescent and inflammation-activated astrocytes: A potentially neuroprotective control of iron burden
- (2013) Ilaria Pelizzoni et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE
- Study of the transcytosis of an anti-transferrin receptor antibody with a Fab′ cargo across the blood–brain barrier in mice
- (2013) Gemma Manich et al. EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES
- Ferroportin and Exocytoplasmic Ferroxidase Activity Are Required for Brain Microvascular Endothelial Cell Iron Efflux
- (2013) Ryan C. McCarthy et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Iron metabolism in the CNS: implications for neurodegenerative diseases
- (2013) Tracey A. Rouault NATURE REVIEWS NEUROSCIENCE
- Expression and localization of duodenal cytochrome b in the rat hippocampus after kainate-induced excitotoxicity
- (2013) S.-Y. Loke et al. NEUROSCIENCE
- Cellular Catabolism of the Iron-Regulatory Peptide Hormone Hepcidin
- (2013) Gloria Cuevas Preza et al. PLoS One
- The Amyloid Precursor Protein (APP) Does Not Have a Ferroxidase Site in Its E2 Domain
- (2013) Kourosh Honarmand Ebrahimi et al. PLoS One
- The systemic iron-regulatory proteins hepcidin and ferroportin are reduced in the brain in Alzheimer’s disease
- (2013) Animesh Raha et al. Acta Neuropathologica Communications
- Iron repletion relocalizes hephaestin to a proximal basolateral compartment in polarized MDCK and Caco2 cells
- (2012) Seung-Min Lee et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Ferroportin-mediated iron transport: Expression and regulation
- (2012) Diane M. Ward et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH
- Mechanistic analysis of iron accumulation by endothelial cells of the BBB
- (2012) Ryan C. McCarthy et al. BIOMETALS
- Molecular Mechanism of Hepcidin-Mediated Ferroportin Internalization Requires Ferroportin Lysines, Not Tyrosines or JAK-STAT
- (2012) Sandra L. Ross et al. Cell Metabolism
- Hepcidin-Induced Endocytosis of Ferroportin Is Dependent on Ferroportin Ubiquitination
- (2012) Bo Qiao et al. Cell Metabolism
- ZIP8 Is an Iron and Zinc Transporter Whose Cell-surface Expression Is Up-regulated by Cellular Iron Loading
- (2012) Chia-Yu Wang et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Intranasal deferoxamine reverses iron-induced memory deficits and inhibits amyloidogenic APP processing in a transgenic mouse model of Alzheimer's disease
- (2012) Chuang Guo et al. NEUROBIOLOGY OF AGING
- Deferoxamine inhibits iron induced hippocampal tau phosphorylation in the Alzheimer transgenic mouse brain
- (2012) Chuang Guo et al. NEUROCHEMISTRY INTERNATIONAL
- A Synthetic Peptide with the Putative Iron Binding Motif of Amyloid Precursor Protein (APP) Does Not Catalytically Oxidize Iron
- (2012) Kourosh Honarmand Ebrahimi et al. PLoS One
- Impairment of Interrelated Iron- and Copper Homeostatic Mechanisms in Brain Contributes to the Pathogenesis of Neurodegenerative Disorders
- (2012) Tina Skjørringe et al. Frontiers in Pharmacology
- Zip14 is a complex broad-scope metal-ion transporter whose functional properties support roles in the cellular uptake of zinc and nontransferrin-bound iron
- (2011) Jorge J. Pinilla-Tenas et al. AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY
- The iron transporter ferroportin can also function as a manganese exporter
- (2011) Michael S. Madejczyk et al. BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES
- Heterogenous distribution of ferroportin-containing neurons in mouse brain
- (2011) Michael W. Boserup et al. BIOMETALS
- Hepcidin regulates ferroportin expression and intracellular iron homeostasis of erythroblasts
- (2011) D.-L. Zhang et al. BLOOD
- Hepcidin directly inhibits transferrin receptor 1 expression in astrocytes via a cyclic AMP-protein kinase a pathway
- (2011) Fang Du et al. GLIA
- H-ferritin is the major source of iron for oligodendrocytes
- (2011) Bozho Todorich et al. GLIA
- Aluminum, copper, iron and zinc differentially alter amyloid-Aβ1–42 aggregation and toxicity
- (2011) Silvia Bolognin et al. INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY
- Soluble A Seeds Are Potent Inducers of Cerebral -Amyloid Deposition
- (2011) F. Langer et al. JOURNAL OF NEUROSCIENCE
- Iron Efflux from Oligodendrocytes Is Differentially Regulated in Gray and White Matter
- (2011) K. Schulz et al. JOURNAL OF NEUROSCIENCE
- Two routes of iron accumulation in astrocytes: ascorbate-dependent ferrous iron uptake via the divalent metal transporter (DMT1) plus an independent route for ferric iron
- (2010) Darius J.R. Lane et al. BIOCHEMICAL JOURNAL
- Role of Citrate and Phosphate Anions in the Mechanism of Iron(III) Sequestration by Ferric Binding Protein: Kinetic Studies of the Formation of the Holoprotein of Wild-Type FbpA and Its Engineered Mutants
- (2010) Katherine D. Weaver et al. BIOCHEMISTRY
- Biological effects of mutant ceruloplasmin on hepcidin-mediated internalization of ferroportin
- (2010) Satoshi Kono et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE
- Iron in neuronal function and dysfunction
- (2010) Gabriela A. Salvador BIOFACTORS
- Human mutation D157G in ferroportin leads to hepcidin-independent binding of Jak2 and ferroportin down-regulation
- (2010) I. De Domenico et al. BLOOD
- Iron-Export Ferroxidase Activity of β-Amyloid Precursor Protein Is Inhibited by Zinc in Alzheimer's Disease
- (2010) James A. Duce et al. CELL
- Transient Expression of Iron Transport Proteins in the Capillary of the Developing Rat Brain
- (2010) W. M. Yang et al. CELLULAR AND MOLECULAR NEUROBIOLOGY
- The transition metals copper and iron in neurodegenerative diseases
- (2010) Susana Rivera-Mancía et al. CHEMICO-BIOLOGICAL INTERACTIONS
- Brain Endothelial Cells Produce Amyloid β from Amyloid Precursor Protein 770 and Preferentially Secrete theO-Glycosylated Form
- (2010) Shinobu Kitazume et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Selective Translational Control of the Alzheimer Amyloid Precursor Protein Transcript by Iron Regulatory Protein-1
- (2010) Hyun-Hee Cho et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- ZRT/IRT-like Protein 14 (ZIP14) Promotes the Cellular Assimilation of Iron from Transferrin
- (2010) Ningning Zhao et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Identification of Zyklopen, a New Member of the Vertebrate Multicopper Ferroxidase Family, and Characterization in Rodents and Human Cells
- (2010) Huijun Chen et al. JOURNAL OF NUTRITION
- Quantitative Mass Spectrometry-based Proteomics Reveals the Dynamic Range of Primary Mouse Astrocyte Protein Secretion
- (2010) Todd M. Greco et al. JOURNAL OF PROTEOME RESEARCH
- The culprit behind amyloid beta peptide related neurotoxicity in Alzheimer's disease: oligomer size or conformation?
- (2010) Kerensa Broersen et al. Alzheimers Research & Therapy
- Functional analysis and theoretical modeling of ferroportin reveals clustering of mutations according to phenotype
- (2009) Daniel F. Wallace et al. AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY
- Cellular and subcellular localizations of nonheme ferric and ferrous iron in the rat brain: a light and electron microscopic study by the perfusion-Perls and -Turnbull methods
- (2009) Reiko Meguro et al. ARCHIVES OF HISTOLOGY AND CYTOLOGY
- Role of hepcidin in murine brain iron metabolism
- (2009) S.-M. Wang et al. CELLULAR AND MOLECULAR LIFE SCIENCES
- Increasing expression of H- or L-ferritin protects cortical astrocytes from hemin toxicity
- (2009) Zhi Li et al. FREE RADICAL RESEARCH
- Human serum transferrin: a tale of two lobes. Urea gel and steady state fluorescence analysis of recombinant transferrins as a function of pH, time, and the soluble portion of the transferrin receptor
- (2009) Shaina L. Byrne et al. JOURNAL OF BIOLOGICAL INORGANIC CHEMISTRY
- The Unique Kinetics of Iron Release from Transferrin: The Role of Receptor, Lobe–Lobe Interactions, and Salt at Endosomal pH
- (2009) Shaina L. Byrne et al. JOURNAL OF MOLECULAR BIOLOGY
- Ferroportin is a manganese-responsive protein that decreases manganese cytotoxicity and accumulation
- (2009) Zhaobao Yin et al. JOURNAL OF NEUROCHEMISTRY
- Age-dependent expression of hephaestin in the brain of ceruloplasmin-deficient mice
- (2009) Rui Cui et al. JOURNAL OF TRACE ELEMENTS IN MEDICINE AND BIOLOGY
- Brain iron homeostasis, the choroid plexus, and localization of iron transport proteins
- (2009) Tracey A. Rouault et al. METABOLIC BRAIN DISEASE
- Iron and the translation of the amyloid precursor protein (APP) and ferritin mRNAs: riboregulation against neural oxidative damage in Alzheimer's disease
- (2008) Jack T. Rogers et al. BIOCHEMICAL SOCIETY TRANSACTIONS
- RETRACTED: The Hepcidin-Binding Site on Ferroportin Is Evolutionarily Conserved
- (2008) Ivana De Domenico et al. Cell Metabolism
- Dcytb (Cybrd1) functions as both a ferric and a cupric reductase in vitro
- (2008) Steven Wyman et al. FEBS LETTERS
- Oligodendrocytes and myelination: The role of iron
- (2008) Bozho Todorich et al. GLIA
- Non-transferrin Iron Reduction and Uptake Are Regulated by Transmembrane Ascorbate Cycling in K562 Cells
- (2008) Darius J. R. Lane et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Slc39a14 Gene Encodes ZIP14, A Metal/Bicarbonate Symporter: Similarities to the ZIP8 Transporter
- (2008) K. Girijashanker et al. MOLECULAR PHARMACOLOGY
- Divalent metal transporter 1 (DMT1) contributes to neurodegeneration in animal models of Parkinson's disease
- (2008) J. Salazar et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Cd2+ versus Zn2+ uptake by the ZIP8 HCO3--dependent symporter: Kinetics, electrogenicity and trafficking
- (2007) Zhiwei Liu et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
Find Funding. Review Successful Grants.
Explore over 25,000 new funding opportunities and over 6,000,000 successful grants.
ExplorePublish scientific posters with Peeref
Peeref publishes scientific posters from all research disciplines. Our Diamond Open Access policy means free access to content and no publication fees for authors.
Learn More