Positive and negative influence of the matrix architecture on antitumor immune surveillance

Recent Developments in Myofibroblast Biology

(2012) Boris Hinz et al.   AMERICAN JOURNAL OF PATHOLOGY

Host Responses in Tissue Repair and Fibrosis

(2012) Jeremy S. Duffield et al.   Annual Review of Pathology-Mechanisms of Disease

The race for the prize: T-cell trafficking strategies for optimal surveillance

(2012) M. Lee et al.   BLOOD

Intratumoral macrophages contribute to epithelial-mesenchymal transition in solid tumors

(2012) Anne-Katrine Bonde et al.   BMC CANCER

Marginating Dendritic Cells of the Tumor Microenvironment Cross-Present Tumor Antigens and Stably Engage Tumor-Specific T Cells

(2012) John J. Engelhardt et al.   CANCER CELL

Enzymatic Targeting of the Stroma Ablates Physical Barriers to Treatment of Pancreatic Ductal Adenocarcinoma

(2012) Paolo P. Provenzano et al.   CANCER CELL

Neogenesis of Lymphoid Structures and Antibody Responses Occur in Human Melanoma Metastases

(2012) Arcadi Cipponi et al.   CANCER RESEARCH

Cellular Constituents of Immune Escape within the Tumor Microenvironment

(2012) S. P. Kerkar et al.   CANCER RESEARCH

Blood leukocytes and macrophages of various phenotypes have distinct abilities to form podosomes and to migrate in 3D environments

(2012) Céline Cougoule et al.   EUROPEAN JOURNAL OF CELL BIOLOGY

The extracellular matrix: A dynamic niche in cancer progression

(2012) Pengfei Lu et al.   JOURNAL OF CELL BIOLOGY

Matrix architecture defines the preferential localization and migration of T cells into the stroma of human lung tumors

(2012) Hélène Salmon et al.   JOURNAL OF CLINICAL INVESTIGATION

Macrophages: Central regulators of hepatic fibrogenesis and fibrosis resolution

(2012) Prakash Ramachandran et al.   JOURNAL OF HEPATOLOGY

Tumor-Associated Microglia/Macrophages Enhance the Invasion of Glioma Stem-like Cells via TGF- 1 Signaling Pathway

(2012) X.-z. Ye et al.   JOURNAL OF IMMUNOLOGY

Rationale Behind Targeting Fibroblast Activation Protein-Expressing Carcinoma-Associated Fibroblasts as a Novel Chemotherapeutic Strategy

(2012) W. N. Brennen et al.   MOLECULAR CANCER THERAPEUTICS

Mechanisms of fibrosis: therapeutic translation for fibrotic disease

(2012) Thomas A Wynn et al.   NATURE MEDICINE

Targeting the TGFβ signalling pathway in disease

(2012) Rosemary J. Akhurst et al.   NATURE REVIEWS DRUG DISCOVERY

In Vitro Study of Novel Collagenase (XIAFLEX®) on Dupuytren's Disease Fibroblasts Displays Unique Drug Related Properties

(2012) Farhatullah Syed et al.   PLoS One

TGF-  blockade improves the distribution and efficacy of therapeutics in breast carcinoma by normalizing the tumor stroma

(2012) J. Liu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A Decade of Imaging Cellular Motility and Interaction Dynamics in the Immune System

(2012) R. N. Germain et al.   SCIENCE

Lymphoid tissue structure and HIV-1 infection: life or death for T cells

(2012) Ming Zeng et al.   TRENDS IN IMMUNOLOGY

Tertiary lymphoid organs in infection and autoimmunity

(2012) Katrijn Neyt et al.   TRENDS IN IMMUNOLOGY

Infection-Induced Regulation of Natural Killer Cells by Macrophages and Collagen at the Lymph Node Subcapsular Sinus

(2012) Janine L. Coombes et al.   Cell Reports

Lymphoid Tissue Damage in HIV-1 Infection Depletes Naïve T Cells and Limits T Cell Reconstitution after Antiretroviral Therapy

(2012) Ming Zeng et al.   PLoS Pathogens

Follicular dendritic cells, conduits, lymphatic vessels, and high endothelial venules in tertiary lymphoid organs: Parallels with lymph node stroma

(2012) Sharon Stranford et al.   Frontiers in Immunology

Stromal cells control soluble material and cellular transport in lymph nodes

(2012) Marc Bajénoff   Frontiers in Immunology

Matricellular Proteins: A Sticky Affair with Cancers

(2012) Han Chung Chong et al.   Journal of Oncology

Association of T-Zone Reticular Networks and Conduits with Ectopic Lymphoid Tissues in Mice and Humans

(2011) Alexander Link et al.   AMERICAN JOURNAL OF PATHOLOGY

Aligned Collagen Is a Prognostic Signature for Survival in Human Breast Carcinoma

(2011) Matthew W. Conklin et al.   AMERICAN JOURNAL OF PATHOLOGY

Myeloid cell diversification and complexity: an old concept with new turns in oncology

(2011) Mariacristina Chioda et al.   CANCER AND METASTASIS REVIEWS

Human Solid Tumors Contain High Endothelial Venules: Association with T- and B-Lymphocyte Infiltration and Favorable Prognosis in Breast Cancer

(2011) L. Martinet et al.   CANCER RESEARCH

Characterization of Chemokines and Adhesion Molecules Associated with T cell Presence in Tertiary Lymphoid Structures in Human Lung Cancer

(2011) L. de Chaisemartin et al.   CANCER RESEARCH

Biomechanical Remodeling of the Microenvironment by Stromal Caveolin-1 Favors Tumor Invasion and Metastasis

(2011) Jacky G. Goetz et al.   CELL

Strategies to Enhance Viral Penetration of Solid Tumors

(2011) Elspeth Smith et al.   HUMAN GENE THERAPY

Chemokine nitration prevents intratumoral infiltration of antigen-specific T cells

(2011) Barbara Molon et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Interstitial guidance of cancer invasion

(2011) Pavlo G. Gritsenko et al.   JOURNAL OF PATHOLOGY

Cancer immunotherapy comes of age

(2011) Ira Mellman et al.   NATURE

Balancing forces: architectural control of mechanotransduction

(2011) Christopher C. DuFort et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Early T Cell Signalling Is Reversibly Altered in PD-1+ T Lymphocytes Infiltrating Human Tumors

(2011) Shu-Fang Wang et al.   PLoS One

ECM components guide IL-10 producing regulatory T-cell (TR1) induction from effector memory T-cell precursors

(2011) P. L. Bollyky et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Mesenchymal Transition and Dissemination of Cancer Cells Is Driven by Myeloid-Derived Suppressor Cells Infiltrating the Primary Tumor

(2011) Benjamin Toh et al.   PLOS BIOLOGY

Metastatic Outgrowth Encompasses COL-I, FN1, and POSTN Up-Regulation and Assembly to Fibrillar Networks Regulating Cell Adhesion, Migration, and Growth

(2010) Johanna Soikkeli et al.   AMERICAN JOURNAL OF PATHOLOGY

Alterations of the extracellular matrix in ovarian cancer studied by Second Harmonic Generation imaging microscopy

(2010) Oleg Nadiarnykh et al.   BMC CANCER

Hyaluronan Deficiency in Tumor Stroma Impairs Macrophage Trafficking and Tumor Neovascularization

(2010) N. Kobayashi et al.   CANCER RESEARCH

Matrix Metalloproteinases: Regulators of the Tumor Microenvironment

(2010) Kai Kessenbrock et al.   CELL

The extracellular matrix at a glance

(2010) C. Frantz et al.   JOURNAL OF CELL SCIENCE

Tumor-Induced Disruption of Proximal TCR-Mediated Signal Transduction in Tumor-Infiltrating CD8+ Lymphocytes Inactivates Antitumor Effector Phase

(2010) E. J. Vazquez-Cintron et al.   JOURNAL OF IMMUNOLOGY

Versican expression is associated with tumor-infiltrating CD8-positive T cells and infiltration depth in cervical cancer

(2010) Arko Gorter et al.   MODERN PATHOLOGY

Induction of Lymphoidlike Stroma and Immune Escape by Tumors That Express the Chemokine CCL21

(2010) J. D. Shields et al.   SCIENCE

Suppression of Antitumor Immunity by Stromal Cells Expressing Fibroblast Activation Protein- 

(2010) M. Kraman et al.   SCIENCE

Physico-mechanical aspects of extracellular matrix influences on tumorigenic behaviors

(2010) Edna Cukierman et al.   SEMINARS IN CANCER BIOLOGY

Cell-autonomous and environmental contributions to the interstitial migration of T cells

(2010) Paulus Mrass et al.   Seminars in Immunopathology

Role of stromal myofibroblasts in invasive breast cancer: stromal expression of alpha-smooth muscle actin correlates with worse clinical outcome

(2010) Masako Yamashita et al.   Breast Cancer

Myeloid Cells in the Tumor Microenvironment: Modulation of Tumor Angiogenesis and Tumor Inflammation

(2010) Michael C. Schmid et al.   Journal of Oncology

Polyinosine-Polycytidylic Acid Stimulates Versican Accumulation in the Extracellular Matrix Promoting Monocyte Adhesion

(2009) Susan Potter-Perigo et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Density of tumour stroma is correlated to outcome after adoptive transfer of CD4+ and CD8+ T cells in a murine mammary carcinoma model

(2009) Michele L. Martin et al.   BREAST CANCER RESEARCH AND TREATMENT

Cancer Metastasis Is Accelerated through Immunosuppression during Snail-Induced EMT of Cancer Cells

(2009) Chie Kudo-Saito et al.   CANCER CELL

Matrix Crosslinking Forces Tumor Progression by Enhancing Integrin Signaling

(2009) Kandice R. Levental et al.   CELL

Hepatic recruitment of the inflammatory Gr1+monocyte subset upon liver injury promotes hepatic fibrosis

(2009) Karlin Raja Karlmark et al.   HEPATOLOGY

Behavior of Parasite-Specific Effector CD8+ T Cells in the Brain and Visualization of a Kinesis-Associated System of Reticular Fibers

(2009) Emma H. Wilson et al.   IMMUNITY

Inflammation Recapitulates the Ontogeny of Lymphoid Stromal Cells

(2009) L. Peduto et al.   JOURNAL OF IMMUNOLOGY

Matrix Architecture Dictates Three-Dimensional Migration Modes of Human Macrophages: Differential Involvement of Proteases and Podosome-Like Structures

(2009) E. Van Goethem et al.   JOURNAL OF IMMUNOLOGY

Inflammation enhances myeloid-derived suppressor cell cross-talk by signaling through Toll-like receptor 4

(2009) Stephanie K. Bunt et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Tenascin-C is an endogenous activator of Toll-like receptor 4 that is essential for maintaining inflammation in arthritic joint disease

(2009) Kim Midwood et al.   NATURE MEDICINE

Injectable Collagenase Clostridium Histolyticum for Dupuytren's Contracture

(2009) Lawrence C. Hurst et al.   NEW ENGLAND JOURNAL OF MEDICINE

Immune infiltration in human tumors: a prognostic factor that should not be ignored

(2009) F Pagès et al.   ONCOGENE

Collagen-based cell migration models in vitro and in vivo

(2009) Katarina Wolf et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

Collagen density promotes mammary tumor initiation and progression

(2008) Paolo P Provenzano et al.   BMC Medicine

Matricellular proteins at the crossroad of inflammation and cancer

(2008) Sabina Sangaletti et al.   CANCER LETTERS

Visualizing stromal cell dynamics in different tumor microenvironments by spinning disk confocal microscopy

(2008) M. Egeblad et al.   Disease Models & Mechanisms

Mechanisms of Fibrogenesis

(2008) Tatiana Kisseleva et al.   EXPERIMENTAL BIOLOGY AND MEDICINE

Imaging of Effector Memory T Cells during a Delayed-Type Hypersensitivity Reaction and Suppression by Kv1.3 Channel Block

(2008) Melanie P. Matheu et al.   IMMUNITY

Signaling defects in anti-tumor T cells

(2008) Alan B. Frey et al.   IMMUNOLOGICAL REVIEWS

The conduit system of the lymph node

(2008) R. Roozendaal et al.   INTERNATIONAL IMMUNOLOGY

Podoplanin expression by cancer associated fibroblasts predicts poor prognosis of lung adenocarcinoma

(2008) Akikazu Kawase et al.   INTERNATIONAL JOURNAL OF CANCER

Long-Term Survival for Patients With Non–Small-Cell Lung Cancer With Intratumoral Lymphoid Structures

(2008) Marie-Caroline Dieu-Nosjean et al.   JOURNAL OF CLINICAL ONCOLOGY

Hyaluronan in human tumors: Pathobiological and prognostic messages from cell-associated and stromal hyaluronan

(2008) Raija H. Tammi et al.   SEMINARS IN CANCER BIOLOGY

Fragments of extracellular matrix as mediators of inflammation

(2007) T ADAIRKIRK et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY