Mechanisms of cellular invasion by intracellular parasites

Blocking autophagy to prevent parasite differentiation: A possible new strategy for fighting parasitic infections?

(2014) Vanina E. Alvarez et al.   Autophagy

Functional Dissection ofToxoplasma gondiiPerforin-like Protein 1 Reveals a Dual Domain Mode of Membrane Binding for Cytolysis and Parasite Egress

(2013) Marijo S. Roiko et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Mechanisms of Trypanosoma cruzi persistence in Chagas disease

(2012) Fnu Nagajyothi et al.   CELLULAR MICROBIOLOGY

Vaccination with a DNA Vaccine Coding for Perforin-Like Protein 1 and MIC6 Induces Significant Protective Immunity against Toxoplasma gondii

(2012) Hai-Kuo Yan et al.   Clinical and Vaccine Immunology

The moving junction, a key portal to host cell invasion by apicomplexan parasites

(2012) Bang Shen et al.   CURRENT OPINION IN MICROBIOLOGY

Plasmodium subtilisin-like protease 1 (SUB1): Insights into the active-site structure, specificity and function of a pan-malaria drug target

(2012) Chrislaine Withers-Martinez et al.   INTERNATIONAL JOURNAL FOR PARASITOLOGY

Immunity to Sand Fly Salivary Protein LJM11 Modulates Host Response to Vector-Transmitted Leishmania Conferring Ulcer-Free Protection

(2012) Regis Gomes et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Delayed-Type Hypersensitivity to Sand Fly Saliva in Humans from a Leishmaniasis-Endemic Area of Mali Is TH1-Mediated and Persists to Midlife

(2012) Fabiano Oliveira et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Hyperlipidemia offers protection againstLeishmania donovaniinfection: role of membrane cholesterol

(2012) June Ghosh et al.   JOURNAL OF LIPID RESEARCH

A Phase 3 Trial of RTS,S/AS01 Malaria Vaccine in African Infants

(2012)   NEW ENGLAND JOURNAL OF MEDICINE

Identification of a New Rhoptry Neck Complex RON9/RON10 in the Apicomplexa Parasite Toxoplasma gondii

(2012) Mauld H. Lamarque et al.   PLoS One

Plasmodium falciparum Field Isolates from South America Use an Atypical Red Blood Cell Invasion Pathway Associated with Invasion Ligand Polymorphisms

(2012) Mary Lopez-Perez et al.   PLoS One

Critical role for phosphoinositide 3-kinase gamma in parasite invasion and disease progression of cutaneous leishmaniasis

(2012) H. E. Cummings et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Receptor-mediated phagocytosis of Leishmania: implications for intracellular survival

(2012) Norikiyo Ueno et al.   TRENDS IN PARASITOLOGY

Antiparasitical chemotherapy in Chagas’ disease cardiomyopathy: current evidence

(2012) Paulo Marcos Matta Guedes et al.   TROPICAL MEDICINE & INTERNATIONAL HEALTH

Membrane Cholesterol Regulates Lysosome-Plasma Membrane Fusion Events and Modulates Trypanosoma cruzi Invasion of Host Cells

(2012) Bárbara Hissa et al.   PLoS Neglected Tropical Diseases

Efficient Capture of Infected Neutrophils by Dendritic Cells in the Skin Inhibits the Early Anti-Leishmania Response

(2012) Flavia L. Ribeiro-Gomes et al.   PLoS Pathogens

Shedding of TRAP by a Rhomboid Protease from the Malaria Sporozoite Surface Is Essential for Gliding Motility and Sporozoite Infectivity

(2012) Ijeoma Ejigiri et al.   PLoS Pathogens

Enhancing Blockade of Plasmodium falciparum Erythrocyte Invasion: Assessing Combinations of Antibodies against PfRH5 and Other Merozoite Antigens

(2012) Andrew R. Williams et al.   PLoS Pathogens

Cell signaling during Trypanosoma cruzi invasion

(2012) Fernando Y. Maeda et al.   Frontiers in Immunology

Trypanosoma cruzi invades host cells through the activation of endothelin and bradykinin receptors: a converging pathway leading to chagasic vasculopathy

(2011) Daniele Andrade et al.   BRITISH JOURNAL OF PHARMACOLOGY

Super-Resolution Dissection of Coordinated Events during Malaria Parasite Invasion of the Human Erythrocyte

(2011) David T. Riglar et al.   Cell Host & Microbe

Leishmania Repression of Host Translation through mTOR Cleavage Is Required for Parasite Survival and Infection

(2011) Maritza Jaramillo et al.   Cell Host & Microbe

Leishmania major parasite stage-dependent host cell invasion and immune evasion

(2011) Ulf Alexander Wenzel et al.   FASEB JOURNAL

Invasion and intracellular survival by protozoan parasites

(2011) L. David Sibley   IMMUNOLOGICAL REVIEWS

Langerhans cells are negative regulators of the anti-Leishmaniaresponse

(2011) Kordula Kautz-Neu et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Trypanosoma cruzisubverts the sphingomyelinase-mediated plasma membrane repair pathway for cell invasion

(2011) Maria Cecilia Fernandes et al.   JOURNAL OF EXPERIMENTAL MEDICINE

CD40-Modulated Dual-Specificity Phosphatases MAPK Phosphatase (MKP)-1 and MKP-3 Reciprocally Regulate Leishmania major Infection

(2011) N. Srivastava et al.   JOURNAL OF IMMUNOLOGY

Leishmaniasis: complexity at the host–pathogen interface

(2011) Paul Kaye et al.   NATURE REVIEWS MICROBIOLOGY

First Results of Phase 3 Trial of RTS,S/AS01 Malaria Vaccine in African Children

(2011)   NEW ENGLAND JOURNAL OF MEDICINE

Focus on the ringleader: the role of AMA1 in apicomplexan invasion and replication

(2011) Jessica S. Tyler et al.   TRENDS IN PARASITOLOGY

Restoration of IFNγR Subunit Assembly, IFNγ Signaling and Parasite Clearance in Leishmania donovani Infected Macrophages: Role of Membrane Cholesterol

(2011) Subha Sen et al.   PLoS Pathogens

Host Cell Invasion by Toxoplasma gondii Is Temporally Regulated by the Host Microtubule Cytoskeleton

(2010) Kristin R. Sweeney et al.   EUKARYOTIC CELL

Cystatin cures visceral leishmaniasis by NF-κB-mediated proinflammatory response through co-ordination of TLR/MyD88 signaling with p105-Tpl2-ERK pathway

(2010) Susanta Kar et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Reticulocyte and Erythrocyte Binding-Like Proteins Function Cooperatively in Invasion of Human Erythrocytes by Malaria Parasites

(2010) Sash Lopaticki et al.   INFECTION AND IMMUNITY

Intraphagosomal Peroxynitrite as a Macrophage-derived Cytotoxin against InternalizedTrypanosoma cruzi

(2010) María Noel Alvarez et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Interaction betweenPlasmodium falciparumApical Membrane Antigen 1 and the Rhoptry Neck Protein Complex Defines a Key Step in the Erythrocyte Invasion Process of Malaria Parasites

(2010) Dave Richard et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Leishmania Inhibitor of Serine Peptidase 2 Prevents TLR4 Activation by Neutrophil Elastase Promoting Parasite Survival in Murine Macrophages

(2010) M. S. Faria et al.   JOURNAL OF IMMUNOLOGY

Large Urban Outbreak of Orally Acquired Acute Chagas Disease at a School in Caracas, Venezuela

(2010) Belkisyolé Alarcón de Noya et al.   JOURNAL OF INFECTIOUS DISEASES

Dynasore, a Dynamin Inhibitor, Inhibits Trypanosoma cruzi Entry into Peritoneal Macrophages

(2010) Emile S. Barrias et al.   PLoS One

Expanded infectious diseases screening program for Hispanic transplant candidates

(2010) M.A. Fitzpatrick et al.   Transplant Infectious Disease

Keratinocytes Determine Th1 Immunity during Early Experimental Leishmaniasis

(2010) Jan M. Ehrchen et al.   PLoS Pathogens

Rhomboid 4 (ROM4) Affects the Processing of Surface Adhesins and Facilitates Host Cell Invasion by Toxoplasma gondii

(2010) Jeffrey S. Buguliskis et al.   PLoS Pathogens

Neutrophil-Derived CCL3 Is Essential for the Rapid Recruitment of Dendritic Cells to the Site of Leishmania major Inoculation in Resistant Mice

(2010) Mélanie Charmoy et al.   PLoS Pathogens

Lipoxin A4 receptor dependent leishmania infection

(2009) Alexander Wenzel et al.   AUTOIMMUNITY

The autophagic pathway is a key component in the lysosomal dependent entry ofTrypanosoma cruziinto the host cell

(2009) Patricia S. Romano et al.   Autophagy

Host Cell Entry by Apicomplexa Parasites Requires Actin Polymerization in the Host Cell

(2009) Virginie Gonzalez et al.   Cell Host & Microbe

Trypanosoma cruzi GP63 Proteins Undergo Stage-Specific Differential Posttranslational Modification and Are Important for Host Cell Infection

(2009) M. M. Kulkarni et al.   INFECTION AND IMMUNITY

Designing Therapies against Experimental Visceral Leishmaniasis by Modulating the Membrane Fluidity of Antigen-Presenting Cells

(2009) S. Banerjee et al.   INFECTION AND IMMUNITY

Rapid Optimization of a Peptide Inhibitor of Malaria Parasite Invasion by ComprehensiveN-Methyl Scanning

(2009) Karen S. Harris et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The BENEFIT trial: testing the hypothesis that trypanocidal therapy is beneficial for patients with chronic Chagas heart disease

(2009) J Antonio Marin-Neto et al.   MEMORIAS DO INSTITUTO OSWALDO CRUZ

Molecular mechanisms of Trypanosoma cruzi infection by oral route

(2009) Nobuko Yoshida   MEMORIAS DO INSTITUTO OSWALDO CRUZ

MIC6 associates with aldolase in host cell invasion by Toxoplasma gondii

(2009) Bin Zheng et al.   PARASITOLOGY RESEARCH

Leishmania amazonensis promastigotes induce and are killed by neutrophil extracellular traps

(2009) A. B. Guimaraes-Costa et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Trypanosoma cruzi Targets Akt in Host Cells as an Intracellular Antiapoptotic Strategy

(2009) M. V. Chuenkova et al.   Science Signaling

The Leishmania donovani Lipophosphoglycan Excludes the Vesicular Proton-ATPase from Phagosomes by Impairing the Recruitment of Synaptotagmin V

(2009) Adrien F. Vinet et al.   PLoS Pathogens

Export of a Toxoplasma gondii Rhoptry Neck Protein Complex at the Host Cell Membrane to Form the Moving Junction during Invasion

(2009) Sébastien Besteiro et al.   PLoS Pathogens

Novel components of the Apicomplexan moving junction reveal conserved and coccidia-restricted elements

(2008) Kurtis W. Straub et al.   CELLULAR MICROBIOLOGY

Chagas disease and the US blood supply

(2008) Caryn Bern et al.   CURRENT OPINION IN INFECTIOUS DISEASES

Microneme Rhomboid Protease TgROM1 Is Required for Efficient Intracellular Growth ofToxoplasma gondii

(2008) Fabien Brossier et al.   EUKARYOTIC CELL

Trypanosoma cruzi in Brazilian Amazonia: Lineages TCI and TCIIa in wild primates, Rhodnius spp. and in humans with Chagas disease associated with oral transmission

(2008) Arlei Marcili et al.   INTERNATIONAL JOURNAL FOR PARASITOLOGY

Microneme protein 8 - a new essential invasion factor in Toxoplasma gondii

(2008) H. Kessler et al.   JOURNAL OF CELL SCIENCE

Quantification of the infectious dose of Leishmania major transmitted to the skin by single sand flies

(2008) N. Kimblin et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Immunity to a salivary protein of a sand fly vector protects against the fatal outcome of visceral leishmaniasis in a hamster model

(2008) R. Gomes et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

In Vivo Imaging Reveals an Essential Role for Neutrophils in Leishmaniasis Transmitted by Sand Flies

(2008) N. C. Peters et al.   SCIENCE

Asymptomatic Leishmania infantum/chagasi infection in blood donors of western Sicily

(2008) Francesco Scarlata et al.   TRANSACTIONS OF THE ROYAL SOCIETY OF TROPICAL MEDICINE AND HYGIENE

Host-cell invasion by malaria parasites: insights from Plasmodium and Toxoplasma

(2008) Jake Baum et al.   TRENDS IN PARASITOLOGY

Immunity to Distinct Sand Fly Salivary Proteins Primes the Anti-Leishmania Immune Response towards Protection or Exacerbation of Disease

(2008) Fabiano Oliveira et al.   PLoS Neglected Tropical Diseases

Migratory Dermal Dendritic Cells Act as Rapid Sensors of Protozoan Parasites

(2008) Lai Guan Ng et al.   PLoS Pathogens

Control of Parasitophorous Vacuole Expansion by LYST/Beige Restricts the Intracellular Growth of Leishmania amazonensis

(2008) Jude Wilson et al.   PLoS Pathogens

A Presenilin-like protease associated with Plasmodium falciparum micronemes is involved in erythrocyte invasion

(2007) Xuerong Li et al.   MOLECULAR AND BIOCHEMICAL PARASITOLOGY

Trypanosoma cruzi infection by oral route

(2007) Nobuko Yoshida   PARASITOLOGY INTERNATIONAL