B Lymphocytes in obesity-related adipose tissue inflammation and insulin resistance

CD40 deficiency in mice exacerbates obesity-induced adipose tissue inflammation, hepatic steatosis, and insulin resistance

(2013) Chang-An Guo et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

The Effects of Salsalate on Glycemic Control in Patients With Type 2 Diabetes

(2013) Allison B. Goldfine   ANNALS OF INTERNAL MEDICINE

The Origins and Drivers of Insulin Resistance

(2013) Andrew M.F. Johnson et al.   CELL

Adipose Tissue Macrophages Function As Antigen-Presenting Cells and Regulate Adipose Tissue CD4 + T Cells in Mice

(2013) David L. Morris et al.   DIABETES

B cell activating factor in obesity is regulated by oxidative stress in adipocytes

(2013) Fujimasa Tada et al.   JOURNAL OF CLINICAL BIOCHEMISTRY AND NUTRITION

Innate lymphoid type 2 cells sustain visceral adipose tissue eosinophils and alternatively activated macrophages

(2013) Ari B. Molofsky et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Blockade of B-cell-activating factor signaling enhances hepatic steatosis induced by a high-fat diet and improves insulin sensitivity

(2013) Keitarou Kawasaki et al.   LABORATORY INVESTIGATION

B cells promote inflammation in obesity and type 2 diabetes through regulation of T-cell function and an inflammatory cytokine profile

(2013) J. DeFuria et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Pleiotropic Actions of Insulin Resistance and Inflammation in Metabolic Homeostasis

(2013) J. I. Odegaard et al.   SCIENCE

Obesity-Associated Autoantibody Production Requires AIM to Retain the Immunoglobulin M Immune Complex on Follicular Dendritic Cells

(2013) Satoko Arai et al.   Cell Reports

Autoimmune-mediated glucose intolerance in a mouse model of systemic lupus erythematosus

(2012) Curtis L. Gabriel et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Immune Regulatory Function of B Cells

(2012) Claudia Mauri et al.   Annual Review of Immunology

BAFF Receptor Deficiency Reduces the Development of Atherosclerosis in Mice—Brief Report

(2012) Andrew P. Sage et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

B cells as effectors and regulators of autoimmunity

(2012) Eliana Mariño et al.   AUTOIMMUNITY

Personal Omics Profiling Reveals Dynamic Molecular and Medical Phenotypes

(2012) Rui Chen et al.   CELL

High-fat-diet exposure induces IgG accumulation in hypothalamic microglia

(2012) C.-X. Yi et al.   Disease Models & Mechanisms

Bone structure and B-cell populations, crippled by obesity, are partially rescued by brief daily exposure to low-magnitude mechanical signals

(2012) M. Ete Chan et al.   FASEB JOURNAL

Adipose Tissue Invariant NKT Cells Protect against Diet-Induced Obesity and Metabolic Disorder through Regulatory Cytokine Production

(2012) Lydia Lynch et al.   IMMUNITY

The adaptive immune system as a fundamental regulator of adipose tissue inflammation and insulin resistance

(2012) Shawn Winer et al.   IMMUNOLOGY AND CELL BIOLOGY

Elevated IgG levels against specific bacterial antigens in obese patients with diabetes and in mice with diet-induced obesity and glucose intolerance

(2012) Nadeem Mohammed et al.   METABOLISM-CLINICAL AND EXPERIMENTAL

Regulatory B cells control T-cell autoimmunity through IL-21-dependent cognate interactions

(2012) Ayumi Yoshizaki et al.   NATURE

A metagenome-wide association study of gut microbiota in type 2 diabetes

(2012) Junjie Qin et al.   NATURE

Neutrophils mediate insulin resistance in mice fed a high-fat diet through secreted elastase

(2012) Saswata Talukdar et al.   NATURE MEDICINE

Bariatric Surgery versus Conventional Medical Therapy for Type 2 Diabetes

(2012) Geltrude Mingrone et al.   NEW ENGLAND JOURNAL OF MEDICINE

Depletion of B2 but Not B1a B Cells in BAFF Receptor-Deficient ApoE−/− Mice Attenuates Atherosclerosis by Potently Ameliorating Arterial Inflammation

(2012) Tin Kyaw et al.   PLoS One

CD40L Deficiency Attenuates Diet-Induced Adipose Tissue Inflammation by Impairing Immune Cell Accumulation and Production of Pathogenic IgG-Antibodies

(2012) Dennis Wolf et al.   PLoS One

Increased Gut Permeability and Microbiota Change Associate with Mesenteric Fat Inflammation and Metabolic Dysfunction in Diet-Induced Obese Mice

(2012) Yan Y. Lam et al.   PLoS One

Enhancement of hematopoiesis and lymphopoiesis in diet-induced obese mice

(2012) M. D. Trottier et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

CD40L Deficiency Ameliorates Adipose Tissue Inflammation and Metabolic Manifestations of Obesity in Mice

(2011) Marjorie Poggi et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Bariatric Surgery Reduces Visceral Adipose Inflammation and Improves Endothelial Function in Type 2 Diabetic Mice

(2011) Hanrui Zhang et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Late-onset neutropenia following rituximab therapy in rheumatic diseases: Association with B lymphocyte depletion and infections

(2011) Daniel Tesfa et al.   ARTHRITIS AND RHEUMATISM

Immunologic profile of excessive body weight

(2011) Mansour Taghavi Azar Sharabiani et al.   BIOMARKERS

Deficiency of haematopoietic-cell-derived IL-10 does not exacerbate high-fat-diet-induced inflammation or insulin resistance in mice

(2011) G. M. Kowalski et al.   DIABETOLOGIA

State of the union between metabolism and the immune system in type 2 diabetes

(2011) B S Nikolajczyk et al.   GENES AND IMMUNITY

Leptin Activates Human B Cells to Secrete TNF-α, IL-6, and IL-10 via JAK2/STAT3 and p38MAPK/ERK1/2 Signaling Pathway

(2011) Sudhanshu Agrawal et al.   JOURNAL OF CLINICAL IMMUNOLOGY

Gut microbiome, obesity, and metabolic dysfunction

(2011) Herbert Tilg et al.   JOURNAL OF CLINICAL INVESTIGATION

Human B1 cells in umbilical cord and adult peripheral blood express the novel phenotype CD20+CD27+CD43+CD70−

(2011) Daniel O. Griffin et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Crosstalk between B lymphocytes, microbiota and the intestinal epithelium governs immunity versus metabolism in the gut

(2011) Natalia Shulzhenko et al.   NATURE MEDICINE

B cells promote insulin resistance through modulation of T cells and production of pathogenic IgG antibodies

(2011) Daniel A Winer et al.   NATURE MEDICINE

B Cell-Activating Factor Controls the Production of Adipokines and Induces Insulin Resistance

(2011) Maho Hamada et al.   Obesity

Eosinophils Sustain Adipose Alternatively Activated Macrophages Associated with Glucose Homeostasis

(2011) D. Wu et al.   SCIENCE

Macrophages, Inflammation, and Insulin Resistance

(2010) Jerrold M. Olefsky et al.   Annual Review of Physiology

Endoplasmic Reticulum Stress and the Inflammatory Basis of Metabolic Disease

(2010) Gökhan S. Hotamisligil   CELL

Toll-like receptors regulate B cell cytokine production in patients with diabetes

(2010) M. Jagannathan et al.   DIABETOLOGIA

Memory B and memory plasma cells

(2010) Taketoshi Yoshida et al.   IMMUNOLOGICAL REVIEWS

B cell depletion reduces the development of atherosclerosis in mice

(2010) Hafid Ait-Oufella et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Conventional B2 B Cell Depletion Ameliorates whereas Its Adoptive Transfer Aggravates Atherosclerosis

(2010) T. Kyaw et al.   JOURNAL OF IMMUNOLOGY

Elevated Proinflammatory Cytokine Production by a Skewed T Cell Compartment Requires Monocytes and Promotes Inflammation in Type 2 Diabetes

(2010) M. Jagannathan-Bogdan et al.   JOURNAL OF IMMUNOLOGY

B Cells Are Required for Optimal CD4+ and CD8+ T Cell Tumor Immunity: Therapeutic B Cell Depletion Enhances B16 Melanoma Growth in Mice

(2010) D. J. DiLillo et al.   JOURNAL OF IMMUNOLOGY

Childhood Obesity, Other Cardiovascular Risk Factors, and Premature Death

(2010) Paul W. Franks et al.   NEW ENGLAND JOURNAL OF MEDICINE

Post-Streptococcal Auto-Antibodies Inhibit Protein Disulfide Isomerase and Are Associated with Insulin Resistance

(2010) Adi Aran et al.   PLoS One

T-Lymphocyte Responses to Intestinally Absorbed Antigens Can Contribute to Adipose Tissue Inflammation and Glucose Intolerance during High Fat Feeding

(2010) Yuehui Wang et al.   PLoS One

Leptin signaling maintains B-cell homeostasis via induction of Bcl-2 and Cyclin D1

(2010) Q. L. K. Lam et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Adaptive immunity and adipose tissue biology

(2010) Denise A. Kaminski et al.   TRENDS IN IMMUNOLOGY

Unexpected trafficking of immune cells within the adipose tissue during the onset of obesity

(2009) Carine Duffaut et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

The C3a Anaphylatoxin Receptor Is a Key Mediator of Insulin Resistance and Functions by Modulating Adipose Tissue Macrophage Infiltration and Activation

(2009) Y. Mamane et al.   DIABETES

Interleukin-10 Prevents Diet-Induced Insulin Resistance by Attenuating Macrophage and Cytokine Response in Skeletal Muscle

(2009) E.-G. Hong et al.   DIABETES

Autoantibodies to glial fibrillary acid protein and S100β in diabetic patients

(2009) I. Gómez-Touriño et al.   DIABETIC MEDICINE

Associations between autoantibodies against apolipoprotein B-100 peptides and vascular complications in patients with type 2 diabetes

(2009) G. N. Fredrikson et al.   DIABETOLOGIA

Omental Milky Spots Develop in the Absence of Lymphoid Tissue-Inducer Cells and Support B and T Cell Responses to Peritoneal Antigens

(2009) Javier Rangel-Moreno et al.   IMMUNITY

Adipocyte Apoptosis, a Link between Obesity, Insulin Resistance, and Hepatic Steatosis

(2009) Naim Alkhouri et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Autoantibodies in Type 2 Diabetes Induce Stress Fiber Formation and Apoptosis in Endothelial Cells

(2009) Mark B. Zimering et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Deletion of Fas in adipocytes relieves adipose tissue inflammation and hepatic manifestations of obesity in mice

(2009) Stephan Wueest et al.   JOURNAL OF CLINICAL INVESTIGATION

Innate production of TH2 cytokines by adipose tissue-associated c-Kit+Sca-1+ lymphoid cells

(2009) Kazuyo Moro et al.   NATURE

Lean, but not obese, fat is enriched for a unique population of regulatory T cells that affect metabolic parameters

(2009) Markus Feuerer et al.   NATURE MEDICINE

CD8+ effector T cells contribute to macrophage recruitment and adipose tissue inflammation in obesity

(2009) Satoshi Nishimura et al.   NATURE MEDICINE

Normalization of obesity-associated insulin resistance through immunotherapy

(2009) Shawn Winer et al.   NATURE MEDICINE

Crucial Role for BAFF-BAFF-R Signaling in the Survival and Maintenance of Mature B Cells

(2009) Melanie Rauch et al.   PLoS One

Chylomicrons Promote Intestinal Absorption and Systemic Dissemination of Dietary Antigen (Ovalbumin) in Mice

(2009) Yuehui Wang et al.   PLoS One

Sera from Patients with Type 2 Diabetes Contain Agonistic Autoantibodies Against G Protein-Coupled Receptors

(2009) P. Hempel et al.   SCANDINAVIAN JOURNAL OF IMMUNOLOGY

B lymphocytes: how they develop and function

(2008) T. W. LeBien et al.   BLOOD

Peripheral B cell subsets

(2008) David Allman et al.   CURRENT OPINION IN IMMUNOLOGY

Cytokine-producing B lymphocytes—key regulators of immunity

(2008) Frances E Lund   CURRENT OPINION IN IMMUNOLOGY

A Regulatory B Cell Subset with a Unique CD1dhiCD5+ Phenotype Controls T Cell-Dependent Inflammatory Responses

(2008) Koichi Yanaba et al.   IMMUNITY

B-lymphocyte contributions to human autoimmune disease

(2008) Koichi Yanaba et al.   IMMUNOLOGICAL REVIEWS

Dual role for B-1a cells in immunity to influenza virus infection

(2008) Youn Soo Choi et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Chylomicrons promote intestinal absorption of lipopolysaccharides

(2008) Sarbani Ghoshal et al.   JOURNAL OF LIPID RESEARCH

Neutrophils transiently infiltrate intra-abdominal fat early in the course of high-fat feeding

(2008) Vered Elgazar-Carmon et al.   JOURNAL OF LIPID RESEARCH

A role for leptin in sustaining lymphopoiesis and myelopoiesis

(2008) K. Claycombe et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The ‘short’ history of regulatory B cells

(2007) Claudia Mauri et al.   TRENDS IN IMMUNOLOGY