Silencing of RB1 but not of RB2/P130 induces cellular senescence and impairs the differentiation potential of human mesenchymal stem cells

How to become immortal: let MEFs count the ways

(2016) Adam Odell et al.   Aging-US

Low concentrations of isothiocyanates protect mesenchymal stem cells from oxidative injuries, while high concentrations exacerbate DNA damage

(2012) Fulvia Zanichelli et al.   APOPTOSIS

Dose-dependent effects of R-sulforaphane isothiocyanate on the biology of human mesenchymal stem cells, at dietary amounts, it promotes cell proliferation and reduces senescence and apoptosis, while at anti-cancer drug doses, it has a cytotoxic effect

(2011) Fulvia Zanichelli et al.   AGE

Elevated transcription of the p53 gene in early S-phase leads to a rapid DNA-damage response during S-phase of the cell cycle

(2011) Paula Takahashi et al.   APOPTOSIS

The switch from pRb/p105 to Rb2/p130 in DNA damage and cellular senescence

(2011) Heike Helmbold et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Dissecting the Unique Role of the Retinoblastoma Tumor Suppressor during Cellular Senescence

(2010) Agustin Chicas et al.   CANCER CELL

Long-term Cultures of Bone Marrow–Derived Human Mesenchymal Stem Cells Frequently Undergo Spontaneous Malignant Transformation

(2009) Gro Vatne Røsland et al.   CANCER RESEARCH

Epstein–Barr Virus-Induced Expression of a Novel Human Vault RNA

(2009) Constanze Nandy et al.   JOURNAL OF MOLECULAR BIOLOGY

Changes in Retinoblastoma Cell Adhesion Associated with Optic Nerve Invasion

(2009) N. Laurie et al.   MOLECULAR AND CELLULAR BIOLOGY

Protocols to detect senescence-associated beta-galactosidase (SA-βgal) activity, a biomarker of senescent cells in culture and in vivo

(2009) Florence Debacq-Chainiaux et al.   Nature Protocols

Hematopoietic stem cell ageing is uncoupled from p16INK4A-mediated senescence

(2009) J L Attema et al.   ONCOGENE

Rb2/p130 is the dominating pocket protein in the p53–p21 DNA damage response pathway leading to senescence

(2009) H Helmbold et al.   ONCOGENE

Nucleolus, Ribosomes, and Cancer

(2008) Lorenzo Montanaro et al.   AMERICAN JOURNAL OF PATHOLOGY

Redox Regulation of Stem and Progenitor Cells

(2008) Laura S. Haneline   ANTIOXIDANTS & REDOX SIGNALING

Mechanism of oxidative DNA damage repair and relevance to human pathology

(2007) M DERRICO et al.   MUTATION RESEARCH-REVIEWS IN MUTATION RESEARCH