ING1 and ING2: multifaceted tumor suppressor genes

The Dark Side of E2F1: In Transit beyond Apoptosis

(2012) D. Engelmann et al.   CANCER RESEARCH

p63/p73 in the control of cell cycle and cell death

(2012) N. Allocati et al.   EXPERIMENTAL CELL RESEARCH

ING1 and 5-Azacytidine Act Synergistically to Block Breast Cancer Cell Growth

(2012) Satbir Thakur et al.   PLoS One

Identification of a Novel Function for the Chromatin Remodeling Protein ING2 in Muscle Differentiation

(2012) Shawn A. Eapen et al.   PLoS One

Proliferating Cell Nuclear Antigen (PCNA) Interactions in Solution Studied by NMR

(2012) Alfredo De Biasio et al.   PLoS One

Genetic Events That Shape the Cancer Epigenome

(2012) R. J. H. Ryan et al.   SCIENCE

Active DNA demethylation by Gadd45 and DNA repair

(2012) Christof Niehrs et al.   TRENDS IN CELL BIOLOGY

Nucleolar protein CSIG is required for p33ING1 function in UV-induced apoptosis

(2012) N Li et al.   Cell Death & Disease

Hallmarks of Cancer: The Next Generation

(2011) Douglas Hanahan et al.   CELL

Cancerous miRNAs and their regulation

(2011) Xu-Bao Shi et al.   CELL CYCLE

p73 tumor suppressor protein: A close relative of p53 not only in structure but also in anti-cancer approach?

(2011) Joanna Zawacka-Pankau et al.   CELL CYCLE

p63 is a suppressor of tumorigenesis and metastasis interacting with mutant p53

(2011) G Melino   CELL DEATH AND DIFFERENTIATION

The tumor suppressor p33ING1bupregulates p16INK4aexpression and induces cellular senescence

(2011) Na Li et al.   FEBS LETTERS

Tumour suppressor ING1b maintains genomic stability upon replication stress

(2011) Ronald P. C. Wong et al.   NUCLEIC ACIDS RESEARCH

The p53 Tumor Suppressor Is Stabilized by Inhibitor of Growth 1 (ING1) by Blocking Polyubiquitination

(2011) Subhash Thalappilly et al.   PLoS One

SMURF1 Amplification Promotes Invasiveness in Pancreatic Cancer

(2011) Kevin A. Kwei et al.   PLoS One

The tumor suppressor ING1 contributes to epigenetic control of cellular senescence

(2010) María Abad et al.   AGING CELL

Regulation of the MicroRNA Processor DGCR8 by the Tumor Suppressor ING1

(2010) D. Gomez-Cabello et al.   CANCER RESEARCH

SharING out the roles in replicatING DNA

(2010) Delphine Larrieu et al.   CELL CYCLE

ING2 controls the G1to S-phase transition by regulating p21 expression

(2010) Delphine Larrieu et al.   CELL CYCLE

Transforming growth factor-β and the hallmarks of cancer

(2010) Maozhen Tian et al.   CELLULAR SIGNALLING

Deacetylase Inhibitors Dissociate the Histone-Targeting ING2 Subunit from the Sin3 Complex

(2010) Karen T. Smith et al.   CHEMISTRY & BIOLOGY

Interplay of bromodomain and histone acetylation in the regulation of p300-dependent genes

(2010) Jihong Chen et al.   Epigenetics

HECT ubiquitin ligase Smurf1 targets the tumor suppressor ING2 for ubiquitination and degradation

(2010) Jing Nie et al.   FEBS LETTERS

The Dimeric Structure and the Bivalent Recognition of H3K4me3 by the Tumor Suppressor ING4 Suggests a Mechanism for Enhanced Targeting of the HBO1 Complex to Chromatin

(2010) Alicia Palacios et al.   JOURNAL OF MOLECULAR BIOLOGY

Sumoylation of ING2 regulates the transcription mediated by Sin3A

(2010) D Ythier et al.   ONCOGENE

Targeted Disruption of Ing2 Results in Defective Spermatogenesis and Development of Soft-Tissue Sarcomas

(2010) Motonobu Saito et al.   PLoS One

ING2 controls the progression of DNA replication forks to maintain genome stability

(2009) Delphine Larrieu et al.   EMBO REPORTS

MMR/c-Abl-dependent activation of ING2/p73α signaling regulates the cell death response to N-methyl-N′-nitro-N-nitrosoguanidine

(2009) Guoming Sun et al.   EXPERIMENTAL CELL RESEARCH

ING2 is upregulated in colon cancer and increases invasion by enhanced MMP13 expression

(2009) Kensuke Kumamoto et al.   INTERNATIONAL JOURNAL OF CANCER

Expression of candidate tumor suppressor gene ING2 is lost in non-small cell lung carcinoma

(2009) Damien Ythier et al.   LUNG CANCER

NMR assignments and histone specificity of the ING2 PHD finger

(2009) Pedro V. Peña et al.   MAGNETIC RESONANCE IN CHEMISTRY

The cancer genome

(2009) Michael R. Stratton et al.   NATURE

Arabidopsis ING and Alfin1-like protein families localize to the nucleus and bind to H3K4me3/2 via plant homeodomain fingers

(2009) Woo Yong Lee et al.   PLANT JOURNAL

The Role of p300 Histone Acetyltransferase in UV-Induced Histone Modifications and MMP-1 Gene Transcription

(2009) Min-Kyoung Kim et al.   PLoS One

ING1a expression increases during replicative senescence and induces a senescent phenotype

(2008) Mohamed A. Soliman et al.   AGING CELL

ING1 protein targeting to the nucleus by karyopherins is necessary for activation of p21

(2008) Michael W. Russell et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Nutlin-3a Activates p53 to Both Down-regulate Inhibitor of Growth 2 and Up-regulate mir-34a, mir-34b, and mir-34c Expression, and Induce Senescence

(2008) K. Kumamoto et al.   CANCER RESEARCH

p37Ing1bRegulates B-Cell Proliferation and Cooperates with p53 to Suppress Diffuse Large B-Cell Lymphomagenesis

(2008) Andrew H. Coles et al.   CANCER RESEARCH

The Inhibitor of Growth (ING) Gene Family: Potential Role in Cancer Therapy

(2008) Mehmet Gunduz et al.   CURRENT CANCER DRUG TARGETS

NAD(P)H quinone oxidoreductase 1 inhibits the proteasomal degradation of the tumour suppressor p33ING1b

(2008) Marco Garate et al.   EMBO REPORTS

A novel ING2 isoform, ING2b, synergizes with ING2a to prevent cell cycle arrest and apoptosis

(2008) Motoko Unoki et al.   FEBS LETTERS

The new tumor suppressor genes ING: Genomic structure and status in cancer

(2008) Damien Ythier et al.   INTERNATIONAL JOURNAL OF CANCER

ING2 as a Novel Mediator of Transforming Growth Factor-β-dependent Responses in Epithelial Cells

(2008) Krishna P. Sarker et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Frequent deletion of ING2 locus at 4q35.1 associates with advanced tumor stage in head and neck squamous cell carcinoma

(2008) Silvia S. Borkosky et al.   JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY

The ING gene family in the regulation of cell growth and tumorigenesis

(2008) Andrew H. Coles et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Histone H3K4me3 Binding Is Required for the DNA Repair and Apoptotic Activities of ING1 Tumor Suppressor

(2008) P.V. Peña et al.   JOURNAL OF MOLECULAR BIOLOGY

CSIG Inhibits PTEN Translation in Replicative Senescence

(2008) L. Ma et al.   MOLECULAR AND CELLULAR BIOLOGY

Tethering by lamin A stabilizes and targets the ING1 tumour suppressor

(2008) Xijing Han et al.   NATURE CELL BIOLOGY

SIRT1 negatively regulates HDAC1-dependent transcriptional repression by the RBP1 family of proteins

(2008) O Binda et al.   ONCOGENE

Decreased expression of ING2 gene and its clinicopathological significance in hepatocellular carcinoma

(2007) Hua-kun Zhang et al.   CANCER LETTERS

Expression profiles of mRNA transcript variants encoding the human inhibitor of growth tumor suppressor gene family in normal and neoplastic tissues

(2007) Alison A. Walzak et al.   EXPERIMENTAL CELL RESEARCH