The substrate degradome of meprin metalloproteases reveals an unexpected proteolytic link between meprin β and ADAM10
Published 2012 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
The substrate degradome of meprin metalloproteases reveals an unexpected proteolytic link between meprin β and ADAM10
Authors
Keywords
Meprin, ADAM10, Metalloproteases, Proteomics, TAILS, Degradome
Journal
CELLULAR AND MOLECULAR LIFE SCIENCES
Volume 70, Issue 2, Pages 309-333
Publisher
Springer Nature
Online
2012-08-31
DOI
10.1007/s00018-012-1106-2
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Protease signalling: the cutting edge
- (2012) Boris Turk et al. EMBO JOURNAL
- Tumor cell-derived Timp-1 is necessary for maintaining metastasis-promoting Met-signaling via inhibition of Adam-10
- (2011) Florian Schelter et al. CLINICAL & EXPERIMENTAL METASTASIS
- The disintegrin/metalloproteinase Adam10 is essential for epidermal integrity and Notch-mediated signaling
- (2011) S. Weber et al. DEVELOPMENT
- Metalloprotease Meprin β Generates Nontoxic N-terminal Amyloid Precursor Protein Fragmentsin Vivo
- (2011) Tamara Jefferson et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Species Specificity of ADAM10 and ADAM17 Proteins in Interleukin-6 (IL-6) Trans-signaling and Novel Role of ADAM10 in Inducible IL-6 Receptor Shedding
- (2011) Christoph Garbers et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Activation of α-secretase cleavage
- (2011) Rolf Postina JOURNAL OF NEUROCHEMISTRY
- Proteomic Analyses Reveal an Acidic Prime Side Specificity for the Astacin Metalloprotease Family Reflected by Physiological Substrates
- (2011) Christoph Becker-Pauly et al. MOLECULAR & CELLULAR PROTEOMICS
- Role of Meprins to Protect Ileal Mucosa of Crohn's Disease Patients from Colonization by Adherent-Invasive E. coli
- (2011) Emilie Vazeille et al. PLoS One
- Enhanced Activity of Meprin-α, a Pro-Migratory and Pro-Angiogenic Protease, in Colorectal Cancer
- (2011) Daniel Lottaz et al. PLoS One
- Balance of meprin A and B in mice affects the progression of experimental inflammatory bowel disease
- (2010) Sanjita Banerjee et al. AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY
- Fetuin-A and Cystatin C Are Endogenous Inhibitors of Human Meprin Metalloproteases
- (2010) Jana Hedrich et al. BIOCHEMISTRY
- Adam10 is essential for early embryonic cardiovascular development
- (2010) Chi Zhang et al. DEVELOPMENTAL DYNAMICS
- ADAM10 is the physiologically relevant, constitutive α-secretase of the amyloid precursor protein in primary neurons
- (2010) Peer-Hendrik Kuhn et al. EMBO JOURNAL
- The “A Disintegrin And Metalloproteases” ADAM10 and ADAM17: Novel drug targets with therapeutic potential?
- (2010) Paul Saftig et al. EUROPEAN JOURNAL OF CELL BIOLOGY
- Processing of Procollagen III by Meprins: New Players in Extracellular Matrix Assembly?
- (2010) Daniel Kronenberg et al. JOURNAL OF INVESTIGATIVE DERMATOLOGY
- Alpha-secretase in Alzheimer’s disease: molecular identity, regulation and therapeutic potential
- (2010) Stefan F. Lichtenthaler JOURNAL OF NEUROCHEMISTRY
- A Statistics-based Platform for Quantitative N-terminome Analysis and Identification of Protease Cleavage Products
- (2010) Ulrich auf dem Keller et al. MOLECULAR & CELLULAR PROTEOMICS
- Multiplex N-terminome Analysis of MMP-2 and MMP-9 Substrate Degradomes by iTRAQ-TAILS Quantitative Proteomics
- (2010) Anna Prudova et al. MOLECULAR & CELLULAR PROTEOMICS
- Isotopic labeling of terminal amines in complex samples identifies protein N-termini and protease cleavage products
- (2010) Oded Kleifeld et al. NATURE BIOTECHNOLOGY
- The secretases: enzymes with therapeutic potential in Alzheimer disease
- (2010) Bart De Strooper et al. Nature Reviews Neurology
- Let It Flow: Morpholino Knockdown in Zebrafish Embryos Reveals a Pro-Angiogenic Effect of the Metalloprotease Meprin α2
- (2010) André Schütte et al. PLoS One
- ADAM10 Releases a Soluble Form of the GPNMB/Osteoactivin Extracellular Domain with Angiogenic Properties
- (2010) April A. N. Rose et al. PLoS One
- A guided tour of the Trans-Proteomic Pipeline
- (2010) Eric W. Deutsch et al. PROTEOMICS
- Meprin A and meprin α generate biologically functional IL-1β from pro-IL-1β
- (2009) Christian Herzog et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Active-site determinants of substrate recognition by the metalloproteinases TACE and ADAM10
- (2009) Cristina I. Caescu et al. BIOCHEMICAL JOURNAL
- Avoiding spam in the proteolytic internet: Future strategies for anti-metastatic MMP inhibition
- (2009) Achim Krüger et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH
- Transforming growth factor- -induced protein (TGFBIp/ ig-h3) activates platelets and promotes thrombogenesis
- (2009) H.-J. Kim et al. BLOOD
- ADAM10, the Rate-limiting Protease of Regulated Intramembrane Proteolysis of Notch and Other Proteins, Is Processed by ADAMS-9, ADAMS-15, and the γ-Secretase
- (2009) Thomas Tousseyn et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Specific processing of tenascin-C by the metalloprotease meprinβ neutralizes its inhibition of cell spreading
- (2009) Daniel Ambort et al. MATRIX BIOLOGY
- MEP1A allele for meprin A metalloprotease is a susceptibility gene for inflammatory bowel disease
- (2009) S Banerjee et al. Mucosal Immunology
- Proteomic identification of multitasking proteins in unexpected locations complicates drug targeting
- (2009) Georgina S. Butler et al. NATURE REVIEWS DRUG DISCOVERY
- Identification of Novel APP/Aβ Isoforms in Human Cerebrospinal Fluid
- (2009) Erik Portelius et al. Neurodegenerative Diseases
- MEROPS: the peptidase database
- (2009) Neil D. Rawlings et al. NUCLEIC ACIDS RESEARCH
- Desmoglein 2 is a substrate of kallikrein 7 in pancreatic cancer
- (2008) Vishnu C Ramani et al. BMC CANCER
- Prointerleukin-18 Is Activated by Meprin βin Vitroandin Vivoin Intestinal Inflammation
- (2008) Sanjita Banerjee et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Activation of the Epidermal Growth Factor Receptor (EGFR) by a Novel Metalloprotease Pathway
- (2008) David A. Bergin et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Meprins, membrane-bound and secreted astacin metalloproteinases
- (2008) E STERCHI et al. MOLECULAR ASPECTS OF MEDICINE
- Protease proteomics: Revealing protease in vivo functions using systems biology approaches
- (2008) A DOUCET et al. MOLECULAR ASPECTS OF MEDICINE
- Proteome-derived, database-searchable peptide libraries for identifying protease cleavage sites
- (2008) Oliver Schilling et al. NATURE BIOTECHNOLOGY
- Metalloprotease Meprinβ in Rat Kidney: Glomerular Localization and Differential Expression in Glomerulonephritis
- (2008) Beatrice Oneda et al. PLoS One
Add your recorded webinar
Do you already have a recorded webinar? Grow your audience and get more views by easily listing your recording on Peeref.
Upload NowAsk a Question. Answer a Question.
Quickly pose questions to the entire community. Debate answers and get clarity on the most important issues facing researchers.
Get Started