Multiplex N-terminome Analysis of MMP-2 and MMP-9 Substrate Degradomes by iTRAQ-TAILS Quantitative Proteomics

A Statistics-based Platform for Quantitative N-terminome Analysis and Identification of Protease Cleavage Products

(2010) Ulrich auf dem Keller et al.   MOLECULAR & CELLULAR PROTEOMICS

Isotopic labeling of terminal amines in complex samples identifies protein N-termini and protease cleavage products

(2010) Oded Kleifeld et al.   NATURE BIOTECHNOLOGY

A guided tour of the Trans-Proteomic Pipeline

(2010) Eric W. Deutsch et al.   PROTEOMICS

Comparative Assessment of Large-Scale Proteomic Studies of Apoptotic Proteolysis

(2009) Gabriel M. Simon et al.   ACS Chemical Biology

Matrix metalloproteinase-9-mediated tissue injury overrides the protective effect of matrix metalloproteinase-2 during colitis

(2009) Pallavi Garg et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

Updated Biological Roles for Matrix Metalloproteinases and New “Intracellular” Substrates Revealed by Degradomics

(2009) Georgina S. Butler et al.   BIOCHEMISTRY

Expression of a protease-resistant insulin-like growth factor-binding protein-4 inhibits tumour growth in a murine model of breast cancer

(2009) A J Ryan et al.   BRITISH JOURNAL OF CANCER

Matrix metalloproteinase proteomics: substrates, targets, and therapy

(2009) Charlotte J Morrison et al.   CURRENT OPINION IN CELL BIOLOGY

Multidimensional degradomics identifies systemic autoantigens and intracellular matrix proteins as novel gelatinase B/MMP-9 substrates

(2009) Bénédicte Cauwe et al.   Integrative Biology

Effect of Matrix Metalloproteinase-9 Knockout on Vein Graft Remodelling in Mice

(2009) Anita C. Thomas et al.   JOURNAL OF VASCULAR RESEARCH

Improved visualization of protein consensus sequences by iceLogo

(2009) Niklaas Colaert et al.   NATURE METHODS

Proteomic identification of multitasking proteins in unexpected locations complicates drug targeting

(2009) Georgina S. Butler et al.   NATURE REVIEWS DRUG DISCOVERY

Single proteins might have dual but related functions in intracellular and extracellular microenvironments

(2009) Derek C. Radisky et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

The protein information and property explorer: an easy-to-use, rich-client web application for the management and functional analysis of proteomic data

(2008) H. Ramos et al.   BIOINFORMATICS

Effect of Ablation or Inhibition of Stromal Matrix Metalloproteinase-9 on Lung Metastasis in a Breast Cancer Model Is Dependent on Genetic Background

(2008) M. D. Martin et al.   CANCER RESEARCH

Global Sequencing of Proteolytic Cleavage Sites in Apoptosis by Specific Labeling of Protein N Termini

(2008) Sami Mahrus et al.   CELL

Global Mapping of the Topography and Magnitude of Proteolytic Events in Apoptosis

(2008) Melissa M. Dix et al.   CELL

Stromal cell-derived factors 1α and 1β, inflammatory protein-10 and interferon-inducible T cell chemo-attractant are novel substrates of dipeptidyl peptidase 8

(2008) Katerina Ajami et al.   FEBS LETTERS

Modulation of M2-type pyruvate kinase activity by the cytoplasmic PML tumor suppressor protein

(2008) Nobukazu Shimada et al.   GENES TO CELLS

Matrix metalloproteinase-9 contributes to intestinal tumourigenesis in the adenomatous polyposis coli multiple intestinal neoplasia mouse

(2008) Mark J. Sinnamon et al.   INTERNATIONAL JOURNAL OF EXPERIMENTAL PATHOLOGY

Multiple Reaction Monitoring of mTRAQ-Labeled Peptides Enables Absolute Quantification of Endogenous Levels of a Potential Cancer Marker in Cancerous and Normal Endometrial Tissues

(2008) Leroi V. DeSouza et al.   JOURNAL OF PROTEOME RESEARCH

An Assessment of Software Solutions for the Analysis of Mass Spectrometry Based Quantitative Proteomics Data

(2008) Lukas N. Mueller et al.   JOURNAL OF PROTEOME RESEARCH

Analysis of Protein Processing by N-terminal Proteomics Reveals Novel Species-specific Substrate Determinants of Granzyme B Orthologs

(2008) Petra Van Damme et al.   MOLECULAR & CELLULAR PROTEOMICS

Metadegradomics

(2008) Alain Doucet et al.   MOLECULAR & CELLULAR PROTEOMICS

Novel MMP-9 Substrates in Cancer Cells Revealed by a Label-free Quantitative Proteomics Approach

(2008) Danmei Xu et al.   MOLECULAR & CELLULAR PROTEOMICS

Pharmacoproteomics of a Metalloproteinase Hydroxamate Inhibitor in Breast Cancer Cells: Dynamics of Membrane Type 1 Matrix Metalloproteinase-Mediated Membrane Protein Shedding

(2008) G. S. Butler et al.   MOLECULAR AND CELLULAR BIOLOGY

Protease proteomics: Revealing protease in vivo functions using systems biology approaches

(2008) A DOUCET et al.   MOLECULAR ASPECTS OF MEDICINE

Proteome-derived, database-searchable peptide libraries for identifying protease cleavage sites

(2008) Oliver Schilling et al.   NATURE BIOTECHNOLOGY

REIC/Dkk-3 induces cell death in human malignant glioma

(2008) Yoshifumi Mizobuchi et al.   NEURO-ONCOLOGY

Pyruvate kinase isozyme type M2 (PKM2) interacts and cooperates with Oct-4 in regulating transcription

(2007) Jungwoon Lee et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY