Expression and functional importance of innate immune receptors by intestinal epithelial cells

Anti-inflammatory capacity of selected lactobacilli in experimental colitis is driven by NOD2-mediated recognition of a specific peptidoglycan-derived muropeptide

(2011) E. M. Fernandez et al.   GUT

Toll-Like Receptor 5 Stimulation Protects Mice from AcuteClostridium difficileColitis

(2011) Irene Jarchum et al.   INFECTION AND IMMUNITY

The association of Streptococcus bovis/gallolyticus with colorectal tumors: The nature and the underlying mechanisms of its etiological role

(2011) Ahmed S Abdulamir et al.   JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH

Nucleotide-Binding Oligomerization Domain 1 Mediates Recognition of Clostridium difficile and Induces Neutrophil Recruitment and Protection against the Pathogen

(2011) M. Hasegawa et al.   JOURNAL OF IMMUNOLOGY

Autophagy in immunity and inflammation

(2011) Beth Levine et al.   NATURE

Meta-analysis identifies 29 additional ulcerative colitis risk loci, increasing the number of confirmed associations to 47

(2011) Carl A Anderson et al.   NATURE GENETICS

Paneth cells, antimicrobial peptides and maintenance of intestinal homeostasis

(2011) Charles L. Bevins et al.   NATURE REVIEWS MICROBIOLOGY

Toll-Like Receptors in Angiogenesis

(2011) Karsten Grote et al.   TheScientificWorldJOURNAL

The Nlrp3 inflammasome: contributions to intestinal homeostasis

(2011) Md. Hasan Zaki et al.   TRENDS IN IMMUNOLOGY

miR-146a Mediates Protective Innate Immune Tolerance in the Neonate Intestine

(2010) Cécilia Chassin et al.   Cell Host & Microbe

NF-κB in the regulation of epithelial homeostasis and inflammation

(2010) Andy Wullaert et al.   CELL RESEARCH

Control of infection by pyroptosis and autophagy: role of TLR and NLR

(2010) Karina R. Bortoluci et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Heads up! How the intestinal epithelium safeguards mucosal barrier immunity through the inflammasome and beyond

(2010) Elke Cario   CURRENT OPINION IN GASTROENTEROLOGY

Bacteria and MAMP-induced morphogenesis of the immune system

(2010) Gérard Eberl et al.   CURRENT OPINION IN IMMUNOLOGY

The inflammasomes: mechanisms of activation and function

(2010) Eicke Latz   CURRENT OPINION IN IMMUNOLOGY

Pathogenic and Protective Roles of MyD88 in Leukocytes and Epithelial Cells in Mouse Models of Inflammatory Bowel Disease

(2010) Mark J. Asquith et al.   GASTROENTEROLOGY

ATG16L1 and NOD2 Interact in an Autophagy-Dependent Antibacterial Pathway Implicated in Crohn's Disease Pathogenesis

(2010) Craig R. Homer et al.   GASTROENTEROLOGY

The NLRP3 Inflammasome Protects against Loss of Epithelial Integrity and Mortality during Experimental Colitis

(2010) Md. Hasan Zaki et al.   IMMUNITY

Control of Intestinal Homeostasis, Colitis, and Colitis-Associated Colorectal Cancer by the Inflammatory Caspases

(2010) Jeremy Dupaul-Chicoine et al.   IMMUNITY

NLRP3 inflammasome plays a key role in the regulation of intestinal homeostasis

(2010) Simon A. Hirota et al.   INFLAMMATORY BOWEL DISEASES

NOD1 contributes to mouse host defense against Helicobacter pylori via induction of type I IFN and activation of the ISGF3 signaling pathway

(2010) Tomohiro Watanabe et al.   JOURNAL OF CLINICAL INVESTIGATION

The NLRP3 inflammasome functions as a negative regulator of tumorigenesis during colitis-associated cancer

(2010) Irving C. Allen et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Bacterial Flagellin Stimulates Toll‐Like Receptor 5–Dependent Defense against Vancomycin‐ResistantEnterococcusInfection

(2010) Melissa A. Kinnebrew et al.   JOURNAL OF INFECTIOUS DISEASES

New Insights into the Regulation of Signalling by Toll-Like Receptors and Nod-Like Receptors

(2010) Rebecca C. Coll et al.   Journal of Innate Immunity

Resequencing of positional candidates identifies low frequency IL23R coding variants protecting against inflammatory bowel disease

(2010) Yukihide Momozawa et al.   NATURE GENETICS

ERK activation drives intestinal tumorigenesis in Apcmin/+ mice

(2010) Sung Hee Lee et al.   NATURE MEDICINE

Recognition of peptidoglycan from the microbiota by Nod1 enhances systemic innate immunity

(2010) Thomas B Clarke et al.   NATURE MEDICINE

Induction and rescue of Nod2-dependent Th1-driven granulomatous inflammation of the ileum

(2010) A. Biswas et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Inflammation-induced tumorigenesis in the colon is regulated by caspase-1 and NLRC4

(2010) B. Hu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

MyD88 signaling in nonhematopoietic cells protects mice against induced colitis by regulating specific EGF receptor ligands

(2010) K. Brandl et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

RIGorous Detection: Exposing Virus Through RNA Sensing

(2010) J. Rehwinkel et al.   SCIENCE

Investigation of innate immunity genes CARD4, CARD8 and CARD15 as germline susceptibility factors for colorectal cancer

(2009) Nikolaus Möckelmann et al.   BMC GASTROENTEROLOGY

The innate immune molecule, NOD1, regulates direct killing ofHelicobacter pyloriby antimicrobial peptides

(2009) Alexandra Grubman et al.   CELLULAR MICROBIOLOGY

Colitis-Associated Variant of TLR2 Causes Impaired Mucosal Repair Because of TFF3 Deficiency

(2009) Daniel K. Podolsky et al.   GASTROENTEROLOGY

Nod2 regulates the host response towards microflora by modulating T cell function and epithelial permeability in mouse Peyer's patches

(2009) F. Barreau et al.   GUT

Differential effects of NOD2 polymorphisms on colorectal cancer risk: a meta-analysis

(2009) Yun Tian et al.   INTERNATIONAL JOURNAL OF COLORECTAL DISEASE

TLR2 Mediates Gap Junctional Intercellular Communication through Connexin-43 in Intestinal Epithelial Barrier Injury

(2009) Birgit Ey et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Induction of microRNA‐155 duringHelicobacter pyloriInfection and Its Negative Regulatory Role in the Inflammatory Response

(2009) Bin Xiao et al.   JOURNAL OF INFECTIOUS DISEASES

A History of Recurrent Positive Selection at the Toll-Like Receptor 5 in Primates

(2009) Gabriela Wlasiuk et al.   MOLECULAR BIOLOGY AND EVOLUTION

Nod1 and Nod2 direct autophagy by recruiting ATG16L1 to the plasma membrane at the site of bacterial entry

(2009) Leonardo H Travassos et al.   NATURE IMMUNOLOGY

NOD2 stimulation induces autophagy in dendritic cells influencing bacterial handling and antigen presentation

(2009) Rachel Cooney et al.   NATURE MEDICINE

Modulation of the Intestinal Microbiota Alters Colitis-Associated Colorectal Cancer Susceptibility

(2009) Joshua M. Uronis et al.   PLoS One

Nod2 is required for the regulation of commensal microbiota in the intestine

(2009) T. Petnicki-Ocwieja et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Toll-like receptors (TLRs) and Nod-like receptors (NLRs) in inflammatory disorders

(2009) Masayuki Fukata et al.   SEMINARS IN IMMUNOLOGY

The Innate Immune Receptor Nod1 Protects the Intestine from Inflammation-Induced Tumorigenesis

(2008) G. Y. Chen et al.   CANCER RESEARCH

Toll-Like Receptor Signaling in Small Intestinal Epithelium Promotes B-Cell Recruitment and IgA Production in Lamina Propria

(2008) Limin Shang et al.   GASTROENTEROLOGY

The Ubiquitin-Editing Enzyme A20 Restricts Nucleotide-Binding Oligomerization Domain Containing 2-Triggered Signals

(2008) Osamu Hitotsumatsu et al.   IMMUNITY

When Signaling Pathways Collide: Positive and Negative Regulation of Toll-like Receptor Signal Transduction

(2008) Luke A.J. O'Neill   IMMUNITY

Toll-Like Receptor 5-Deficient Mice Have Dysregulated Intestinal Gene Expression and Nonspecific Resistance to Salmonella-Induced Typhoid-Like Disease

(2008) M. Vijay-Kumar et al.   INFECTION AND IMMUNITY

Hypomorphic nuclear factor-κB essential modulator mutation database and reconstitution system identifies phenotypic and immunologic diversity

(2008) Eric P. Hanson et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

A key role for autophagy and the autophagy gene Atg16l1 in mouse and human intestinal Paneth cells

(2008) Ken Cadwell et al.   NATURE

Lymphoid tissue genesis induced by commensals through NOD1 regulates intestinal homeostasis

(2008) Djahida Bouskra et al.   NATURE

Vancomycin-resistant enterococci exploit antibiotic-induced innate immune deficits

(2008) Katharina Brandl et al.   NATURE

Common variants in the NLRP3 region contribute to Crohn's disease susceptibility

(2008) Alexandra-Chloé Villani et al.   NATURE GENETICS

TRAM couples endocytosis of Toll-like receptor 4 to the induction of interferon-β

(2008) Jonathan C Kagan et al.   NATURE IMMUNOLOGY

Nod2 Mediates Susceptibility to Yersinia pseudotuberculosis in Mice

(2008) Ulrich Meinzer et al.   PLoS One

Paneth cells directly sense gut commensals and maintain homeostasis at the intestinal host-microbial interface

(2008) S. Vaishnava et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The inner of the two Muc2 mucin-dependent mucus layers in colon is devoid of bacteria

(2008) M. E. V. Johansson et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

MyD88 signalling plays a critical role in host defence by controlling pathogen burden and promoting epithelial cell homeostasis during Citrobacter rodentium-induced colitis

(2007) D. L. Gibson et al.   CELLULAR MICROBIOLOGY