Synphilin-1 inhibits alpha-synuclein degradation by the proteasome

Synphilin-1 attenuates neuronal degeneration in the A53T  -synuclein transgenic mouse model

(2010) W. W. Smith et al.   HUMAN MOLECULAR GENETICS

Methylation Regulates Alpha-Synuclein Expression and Is Decreased in Parkinson's Disease Patients' Brains

(2010) A. Jowaed et al.   JOURNAL OF NEUROSCIENCE

The HSP70 Molecular Chaperone Is Not Beneficial in a Mouse Model of α-synucleinopathy

(2010) Derya R. Shimshek et al.   PLoS One

Evidence That α-Synuclein Does Not Inhibit Phospholipase D†

(2009) Irit Rappley et al.   BIOCHEMISTRY

Intrinsic Protein Disorder and Interaction Promiscuity Are Widely Associated with Dosage Sensitivity

(2009) Tanya Vavouri et al.   CELL

Interaction with synphilin-1 promotes inclusion formation of α-synuclein: mechanistic insights and pathological implication

(2009) Yuan-Yuan Xie et al.   FASEB JOURNAL

Synphilin-1A Inhibits Seven in Absentia Homolog (SIAH) and Modulates α-Synuclein Monoubiquitylation and Inclusion Formation

(2009) Raymonde Szargel et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Cytomegalovirus Promoter Up-regulation Is the Major Cause of Increased Protein Levels of Unstable Reporter Proteins after Treatment of Living Cells with Proteasome Inhibitors

(2009) Beatriz Alvarez-Castelao et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Transgenic overexpression of the alpha-synuclein interacting protein synphilin-1 leads to behavioral and neuropathological alterations in mice

(2009) Silke Nuber et al.   NEUROGENETICS

Autophagy-mediated clearance of aggresomes is not a universal phenomenon

(2008) Esther S.P. Wong et al.   HUMAN MOLECULAR GENETICS

Triggering Aggresome Formation

(2008) Nava Zaarur et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Aggregate formation and toxicity by wild-type and R621C synphilin-1 in the nigrostriatal system of mice using adenoviral vectors

(2008) Antje Krenz et al.   JOURNAL OF NEUROCHEMISTRY