Substrates with Engineered Step Changes in Rigidity Induce Traction Force Polarity and Durotaxis

Mesenchymal stem cell durotaxis depends on substrate stiffness gradient strength

(2013) Ludovic G. Vincent et al.   Biotechnology Journal

Forcing Stem Cells to Behave: A Biophysical Perspective of the Cellular Microenvironment

(2012) Yubing Sun et al.   Annual Review of Biophysics

Substrate stiffness regulates cadherin-dependent collective migration through myosin-II contractility

(2012) Mei Rosa Ng et al.   JOURNAL OF CELL BIOLOGY

Crawling from soft to stiff matrix polarizes the cytoskeleton and phosphoregulates myosin-II heavy chain

(2012) Matthew Raab et al.   JOURNAL OF CELL BIOLOGY

UV-Modulated Substrate Rigidity for Multiscale Study of Mechanoresponsive Cellular Behaviors

(2012) Yubing Sun et al.   LANGMUIR

Evidence of a large-scale mechanosensing mechanism for cellular adaptation to substrate stiffness

(2012) L. Trichet et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Synergistic regulation of cell function by matrix rigidity and adhesive pattern

(2011) Shinuo Weng et al.   BIOMATERIALS

The influence of scaffold elasticity on germ layer specification of human embryonic stem cells

(2011) Janet Zoldan et al.   BIOMATERIALS

Cell Shape and Substrate Rigidity Both Regulate Cell Stiffness

(2011) Shang-You Tee et al.   BIOPHYSICAL JOURNAL

A Mechanoresponsive Cadherin-Keratin Complex Directs Polarized Protrusive Behavior and Collective Cell Migration

(2011) Gregory F. Weber et al.   DEVELOPMENTAL CELL

In situ force mapping of mammary gland transformation

(2011) Jose I. Lopez et al.   Integrative Biology

Myosin IIA/IIB restrict adhesive and protrusive signaling to generate front–back polarity in migrating cells

(2011) Miguel Vicente-Manzanares et al.   JOURNAL OF CELL BIOLOGY

Assessing the spatial resolution of cellular rigidity sensing using a micropatterned hydrogel–photoresist composite

(2011) Ian T. Hoffecker et al.   LAB ON A CHIP

Assaying stem cell mechanobiology on microfabricated elastomeric substrates with geometrically modulated rigidity

(2011) Michael T Yang et al.   Nature Protocols

Cell-ECM traction force modulates endogenous tension at cell-cell contacts

(2011) V. Maruthamuthu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Unidirectional mechanical cellular stimuli via micropost array gradients

(2011) Ryan D. Sochol et al.   Soft Matter

Mechanical regulation of cell function with geometrically modulated elastomeric substrates

(2010) Jianping Fu et al.   NATURE METHODS

Mechanical tugging force regulates the size of cell-cell junctions

(2010) Z. Liu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Substrate Elasticity Regulates Skeletal Muscle Stem Cell Self-Renewal in Culture

(2010) P. M. Gilbert et al.   SCIENCE

Vascular Smooth Muscle Cell Durotaxis Depends on Substrate Stiffness Gradient Strength

(2009) Brett C. Isenberg et al.   BIOPHYSICAL JOURNAL

Actomyosin stiffens the vertebrate embryo during crucial stages of elongation and neural tube closure

(2009) J. Zhou et al.   DEVELOPMENT

Classical cadherins control nucleus and centrosome position and cell polarity

(2009) Isabelle Dupin et al.   JOURNAL OF CELL BIOLOGY

Cell polarity triggered by cell-cell adhesion via E-cadherin

(2009) R. A. Desai et al.   JOURNAL OF CELL SCIENCE

Growth Factors, Matrices, and Forces Combine and Control Stem Cells

(2009) D. E. Discher et al.   SCIENCE

The role of matrix stiffness in regulating cell behavior

(2008) Rebecca G. Wells   HEPATOLOGY

Fabrication of elastomer pillar arrays with modulated stiffness for cellular force measurements

(2008) S. Ghassemi et al.   JOURNAL OF VACUUM SCIENCE & TECHNOLOGY B