Phagosomal signaling byBorrelia burgdorferiin human monocytes involves Toll-like receptor (TLR) 2 and TLR8 cooperativity and TLR8-mediated induction of IFN-β

A Critical Role for Type I IFN in Arthritis Development following Borrelia burgdorferi Infection of Mice

(2014) J. C. Miller et al.   JOURNAL OF IMMUNOLOGY

Macrophage Proinflammatory Response to Francisella tularensis Live Vaccine Strain Requires Coordination of Multiple Signaling Pathways

(2014) L. E. Cole et al.   JOURNAL OF IMMUNOLOGY

Identification of RNA Sequence Motifs Stimulating Sequence-Specific TLR8-Dependent Immune Responses

(2014) A. Forsbach et al.   JOURNAL OF IMMUNOLOGY

Exposure to HIV-1-encoded Toll-like receptor 8 ligands enhances monocyte response to microbial encoded Toll-like receptor 2/4 ligands

(2010) Marianne W Mureith et al.   AIDS

Induction of type I interferons by bacteria

(2010) Kathryn M. Monroe et al.   CELLULAR MICROBIOLOGY

Genetic modulation of TLR8 response following bacterial phagocytosis

(2010) Michael P. Gantier et al.   HUMAN MUTATION

The Lyme Disease Spirochete Borrelia burgdorferi Utilizes Multiple Ligands, Including RNA, for Interferon Regulatory Factor 3-Dependent Induction of Type I Interferon-Responsive Genes

(2010) J. C. Miller et al.   INFECTION AND IMMUNITY

HIV-1 exploits innate signaling by TLR8 and DC-SIGN for productive infection of dendritic cells

(2010) Sonja I Gringhuis et al.   NATURE IMMUNOLOGY

The role of pattern-recognition receptors in innate immunity: update on Toll-like receptors

(2010) Taro Kawai et al.   NATURE IMMUNOLOGY

Murine Toll-Like Receptor 2 Activation Induces Type I Interferon Responses from Endolysosomal Compartments

(2010) Nicole Dietrich et al.   PLoS One

Toll-like receptor 8-mediated activation of murine plasmacytoid dendritic cells by vaccinia viral DNA

(2010) J. Martinez et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Pathogen Recognition and Inflammatory Signaling in Innate Immune Defenses

(2009) T. H. Mogensen   CLINICAL MICROBIOLOGY REVIEWS

TheBorrelia burgdorferi flaBpromoter has an extended −10 element and includes a T-rich −35/−10 spacer sequence that is essential for optimal activity

(2009) Aarti Gautam et al.   FEMS MICROBIOLOGY LETTERS

TLR7 and TLR8 ligands and antiphospholipid antibodies show synergistic effects on the induction of IL-1β and caspase-1 in monocytes and dendritic cells

(2009) Julia Hurst et al.   IMMUNOBIOLOGY

Live Borrelia burgdorferi Spirochetes Elicit Inflammatory Mediators from Human Monocytes via the Toll-Like Receptor Signaling Pathway

(2009) V. A. Dennis et al.   INFECTION AND IMMUNITY

Recognition of Borrelia burgdorferi, the Lyme Disease Spirochete, by TLR7 and TLR9 Induces a Type I IFN Response by Human Immune Cells

(2009) M. M. Petzke et al.   JOURNAL OF IMMUNOLOGY

Bacterial recognition by TLR7 in the lysosomes of conventional dendritic cells

(2009) Giuseppe Mancuso et al.   NATURE IMMUNOLOGY

Toll-like receptor 2 on inflammatory monocytes induces type I interferon in response to viral but not bacterial ligands

(2009) Roman Barbalat et al.   NATURE IMMUNOLOGY

NOD2, RIP2 and IRF5 Play a Critical Role in the Type I Interferon Response to Mycobacterium tuberculosis

(2009) Amit K. Pandey et al.   PLoS Pathogens

Activation of Human Monocytes by Live Borrelia burgdorferi Generates TLR2-Dependent and -Independent Responses Which Include Induction of IFN-β

(2009) Juan C. Salazar et al.   PLoS Pathogens

Recognition of viral single-stranded RNA by Toll-like receptors☆

(2008) S DIEBOLD   ADVANCED DRUG DELIVERY REVIEWS

Toll-like receptor-mediated activation of neutrophils by influenza A virus

(2008) J. P. Wang et al.   BLOOD

TLR-Independent Type I Interferon Induction in Response to an Extracellular Bacterial Pathogen via Intracellular Recognition of Its DNA

(2008) Marie Charrel-Dennis et al.   Cell Host & Microbe

Gene expression profiling provides insights into the pathways involved in inflammatory arthritis development: Murine model of Lyme disease

(2008) Jennifer C. Miller et al.   EXPERIMENTAL AND MOLECULAR PATHOLOGY

Distinct Roles for MyD88 and Toll-Like Receptors 2, 5, and 9 in Phagocytosis of Borrelia burgdorferi and Cytokine Induction

(2008) O. S. Shin et al.   INFECTION AND IMMUNITY

Group A Streptococcus Activates Type I Interferon Production and MyD88-dependent Signaling without Involvement of TLR2, TLR4, and TLR9

(2008) Nina Gratz et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Cellular trafficking of lipoteichoic acid and Toll-like receptor 2 in relation to signaling; role of CD14 and CD36

(2008) Nadra J. Nilsen et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Genetic Association and Expression Studies Indicate a Role of Toll-Like Receptor 8 in Pulmonary Tuberculosis

(2008) Sonia Davila et al.   PLoS Genetics