Therapeutic Potential of MicroRNA Let-7: Tumor Suppression or Impeding Normal Stemness
Published 2014 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Therapeutic Potential of MicroRNA Let-7: Tumor Suppression or Impeding Normal Stemness
Authors
Keywords
-
Journal
CELL TRANSPLANTATION
Volume 23, Issue 4-5, Pages 459-469
Publisher
SAGE Publications
Online
2014-05-08
DOI
10.3727/096368914x678418
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- LIN28B-mediated expression of fetal hemoglobin and production of fetal-like erythrocytes from adult human erythroblasts ex vivo
- (2013) Y. T. Lee et al. BLOOD
- Identification of miRNAs associated with sexual maturity in chicken ovary by Illumina small RNA deep sequencing
- (2013) Li Kang et al. BMC GENOMICS
- Lin28: Primal Regulator of Growth and Metabolism in Stem Cells
- (2013) Ng Shyh-Chang et al. Cell Stem Cell
- The let-7/LIN-41 Pathway Regulates Reprogramming to Human Induced Pluripotent Stem Cells by Controlling Expression of Prodifferentiation Genes
- (2013) Kathleen A. Worringer et al. Cell Stem Cell
- Hypoxia-responsive miRNAs target argonaute 1 to promote angiogenesis
- (2013) Zhen Chen et al. JOURNAL OF CLINICAL INVESTIGATION
- Let-7c MicroRNA Expression and Clinical Significance in Hepatocellular Carcinoma
- (2013) X-M Zhu et al. JOURNAL OF INTERNATIONAL MEDICAL RESEARCH
- The Lin28b–let-7–Hmga2 axis determines the higher self-renewal potential of fetal haematopoietic stem cells
- (2013) Michael R. Copley et al. NATURE CELL BIOLOGY
- Role of Deregulated microRNAs in Breast Cancer Progression Using FFPE Tissue
- (2013) Liang Chen et al. PLoS One
- OstemiR: A Novel Panel of MicroRNA Biomarkers in Osteoblastic and Osteocytic Differentiation from Mesencymal Stem Cells
- (2013) Takanori Eguchi et al. PLoS One
- Distinct microRNA Expression Profile in Prostate Cancer Patients with Early Clinical Failure and the Impact of let-7 as Prognostic Marker in High-Risk Prostate Cancer
- (2013) Maria Schubert et al. PLoS One
- SOX2-LIN28/let-7 pathway regulates proliferation and neurogenesis in neural precursors
- (2013) F. Cimadamore et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- NF-κB and STAT3 signaling pathways collaboratively link inflammation to cancer
- (2013) Yihui Fan et al. Protein & Cell
- Pulmonary microRNA profiling in a mouse model of ventilator-induced lung injury
- (2012) Katerina Vaporidi et al. AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY
- Cancer and Inflammation: An Old Intuition with Rapidly Evolving New Concepts
- (2012) Giorgio Trinchieri Annual Review of Immunology
- The let-7 microRNA enhances heme oxygenase-1 by suppressing Bach1 and attenuates oxidant injury in human hepatocytes
- (2012) Weihong Hou et al. Biochimica et Biophysica Acta-Gene Regulatory Mechanisms
- Mono-Uridylation of Pre-MicroRNA as a Key Step in the Biogenesis of Group II let-7 MicroRNAs
- (2012) Inha Heo et al. CELL
- Synthetic miR-34a Mimics as a Novel Therapeutic Agent for Multiple Myeloma: In Vitro and In Vivo Evidence
- (2012) M. T. Di Martino et al. CLINICAL CANCER RESEARCH
- Role of miRNAs in Muscle Stem Cell Biology: Proliferation, Differentiation and Death
- (2012) Stefania Crippa et al. CURRENT PHARMACEUTICAL DESIGN
- Hormonal activation of let-7-C microRNAs via EcR is required for adult Drosophila melanogaster morphology and function
- (2012) G. Chawla et al. DEVELOPMENT
- Steroid-induced microRNAlet-7acts as a spatio-temporal code for neuronal cell fate in the developingDrosophilabrain
- (2012) Mariya M Kucherenko et al. EMBO JOURNAL
- Whole-genome microRNA screening identifies let-7 and mir-18 as regulators of germ layer formation during early embryogenesis
- (2012) A. R. Colas et al. GENES & DEVELOPMENT
- Lin-28 Homologue A (LIN28A) Promotes Cell Cycle Progression via Regulation of Cyclin-dependent Kinase 2 (CDK2), Cyclin D1 (CCND1), and Cell Division Cycle 25 Homolog A (CDC25A) Expression in Cancer
- (2012) Ning Li et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Differentiation-associated microRNAs antagonize the Rb–E2F pathway to restrict proliferation
- (2012) Matteo J. Marzi et al. JOURNAL OF CELL BIOLOGY
- Differential Regulation of the Let-7 Family of MicroRNAs in CD4+ T Cells Alters IL-10 Expression
- (2012) S. Swaminathan et al. JOURNAL OF IMMUNOLOGY
- MicroRNA expression profiles associated with pancreatic adenocarcinoma and ampullary adenocarcinoma
- (2012) Nicolai A Schultz et al. MODERN PATHOLOGY
- The let-7–Imp axis regulates ageing of the Drosophila testis stem-cell niche
- (2012) Hila Toledano et al. NATURE
- Regulation of the let-7a-3 Promoter by NF-κB
- (2012) David J. Wang et al. PLoS One
- Genomic DNA Copy-Number Alterations of the let-7 Family in Human Cancers
- (2012) Yanling Wang et al. PLoS One
- How does Lin28 let-7 control development and disease?
- (2012) James E. Thornton et al. TRENDS IN CELL BIOLOGY
- MicroRNA profiling predicts survival in anti-EGFR treated chemorefractory metastatic colorectal cancer patients with wild-type KRAS and BRAF
- (2012) Neda Mosakhani et al. Cancer Genetics
- lin-28 Controls the Succession of Cell Fate Choices via Two Distinct Activities
- (2012) Bhaskar Vadla et al. PLoS Genetics
- A LIN28-Dependent Structural Change in pre-let-7g Directly Inhibits Dicer Processing
- (2011) Helen L. Lightfoot et al. BIOCHEMISTRY
- IMP-1 Displays Cross-Talk with K-Ras and Modulates Colon Cancer Cell Survival through the Novel Proapoptotic Protein CYFIP2
- (2011) P. S. Mongroo et al. CANCER RESEARCH
- MicroRNA Sequence and Expression Analysis in Breast Tumors by Deep Sequencing
- (2011) T. A. Farazi et al. CANCER RESEARCH
- Invasion front-specific expression and prognostic significance of microRNA in colorectal liver metastases
- (2011) Christoph Kahlert et al. CANCER SCIENCE
- Lin28A and Lin28B Inhibit let-7 MicroRNA Biogenesis by Distinct Mechanisms
- (2011) Elena Piskounova et al. CELL
- Classification of Non-small Cell Lung Carcinoma in Transthoracic Needle Specimens Using MicroRNA Expression Profiling
- (2011) Ambrogio Fassina et al. CHEST
- MicroRNAs and developmental timing
- (2011) Victor Ambros CURRENT OPINION IN GENETICS & DEVELOPMENT
- Messenger RNA and microRNA profiling during early mouse EB formation
- (2011) Rashmi Tripathi et al. GENE EXPRESSION PATTERNS
- Musashi1 Cooperates in Abnormal Cell Lineage Protein 28 (Lin28)-mediated Let-7 Family MicroRNA Biogenesis in Early Neural Differentiation
- (2011) Hironori Kawahara et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- MYC Protein Inhibits Transcription of the MicroRNA ClusterMC-let-7a-1∼let-7dvia Noncanonical E-box
- (2011) Zifeng Wang et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Functional analysis of microRNAs in human hepatocellular cancer stem cells
- (2011) Fanyin Meng et al. JOURNAL OF CELLULAR AND MOLECULAR MEDICINE
- MicroRNA identity and abundance in developing swine adipose tissue as determined by solexa sequencing
- (2011) Guoxi Li et al. JOURNAL OF CELLULAR BIOCHEMISTRY
- LIN-28 co-transcriptionally binds primary let-7 to regulate miRNA maturation in Caenorhabditis elegans
- (2011) Priscilla M Van Wynsberghe et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- MicroRNAs in Hepatobiliary and Pancreatic Cancers
- (2011) Yoshimasa Saito et al. Frontiers in Genetics
- Epigenetic Down-Regulation of the Tumor Suppressor Gene PRDM1/Blimp-1 in Diffuse Large B Cell Lymphomas
- (2010) Kui Nie et al. AMERICAN JOURNAL OF PATHOLOGY
- The prognostic and functional role of microRNAs in acute myeloid leukemia
- (2010) G. Marcucci et al. BLOOD
- Analysis of microRNA transcriptome by deep sequencing of small RNA libraries of peripheral blood
- (2010) Candida Vaz et al. BMC GENOMICS
- Double-Negative Feedback Loop between Reprogramming Factor LIN28 and microRNA let-7 Regulates Aldehyde Dehydrogenase 1-Positive Cancer Stem Cells
- (2010) X. Yang et al. CANCER RESEARCH
- Lin28: A MicroRNA Regulator with a Macro Role
- (2010) Srinivas R. Viswanathan et al. CELL
- Thioredoxin 1 Negatively Regulates Angiotensin II–Induced Cardiac Hypertrophy Through Upregulation of miR-98/let-7
- (2010) Yanfei Yang et al. CIRCULATION RESEARCH
- Identification of MicroRNAs Regulating Reprogramming FactorLIN28in Embryonic Stem Cells and Cancer Cells
- (2010) Xiaomin Zhong et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- MicroRNA transcriptome in the newborn mouse ovaries determined by massive parallel sequencing
- (2010) Hyo Won Ahn et al. MOLECULAR HUMAN REPRODUCTION
- MicroRNA signature in testes-derived male germ-line stem cells
- (2010) Yoon Hee Jung et al. MOLECULAR HUMAN REPRODUCTION
- Pathogenic LRRK2 negatively regulates microRNA-mediated translational repression
- (2010) Stephan Gehrke et al. NATURE
- Opposing microRNA families regulate self-renewal in mouse embryonic stem cells
- (2010) Collin Melton et al. NATURE
- Transfusion independence and HMGA2 activation after gene therapy of human β-thalassaemia
- (2010) Marina Cavazzana-Calvo et al. NATURE
- Ascl1a regulates Müller glia dedifferentiation and retinal regeneration through a Lin-28-dependent, let-7 microRNA signalling pathway
- (2010) Rajesh Ramachandran et al. NATURE CELL BIOLOGY
- Aging and microRNA expression in human skeletal muscle: a microarray and bioinformatics analysis
- (2010) Micah J. Drummond et al. PHYSIOLOGICAL GENOMICS
- Selected MicroRNAs Define Cell Fate Determination of Murine Central Memory CD8 T Cells
- (2010) Gonzalo Almanza et al. PLoS One
- miRNAs in Newt Lens Regeneration: Specific Control of Proliferation and Evidence for miRNA Networking
- (2010) Kenta Nakamura et al. PLoS One
- Let-7 MicroRNA Family Is Selectively Secreted into the Extracellular Environment via Exosomes in a Metastatic Gastric Cancer Cell Line
- (2010) Keiichi Ohshima et al. PLoS One
- MicroRNA let-7b regulates neural stem cell proliferation and differentiation by targeting nuclear receptor TLX signaling
- (2010) C. Zhao et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- An Epigenetic Switch Involving NF-κB, Lin28, Let-7 MicroRNA, and IL6 Links Inflammation to Cell Transformation
- (2009) Dimitrios Iliopoulos et al. CELL
- The TRIM-NHL Protein TRIM32 Activates MicroRNAs and Prevents Self-Renewal in Mouse Neural Progenitors
- (2009) Jens C. Schwamborn et al. CELL
- TUT4 in Concert with Lin28 Suppresses MicroRNA Biogenesis through Pre-MicroRNA Uridylation
- (2009) Inha Heo et al. CELL
- MicroRNAs and Lung Cancer: New Oncogenes and Tumor Suppressors, New Prognostic Factors and Potential Therapeutic Targets
- (2009) Cecile Ortholan et al. CURRENT MEDICINAL CHEMISTRY
- MicroRNAs and prostate cancer
- (2009) Valeria Coppola et al. ENDOCRINE-RELATED CANCER
- The role of let-7 in cell differentiation and cancer
- (2009) Benjamin Boyerinas et al. ENDOCRINE-RELATED CANCER
- Let-7 microRNAs are developmentally regulated in circulating human erythroid cells
- (2009) Seung-Jae Noh et al. Journal of Translational Medicine
- MicroRNAlet-7Regulates 3T3-L1 Adipogenesis
- (2009) Tingwan Sun et al. MOLECULAR ENDOCRINOLOGY
- Active turnover modulates mature microRNA activity in Caenorhabditis elegans
- (2009) Saibal Chatterjee et al. NATURE
- MicroRNAs Expressed during Lung Cancer Development Are Expressed in Human Pseudoglandular Lung Embryogenesis
- (2009) Alfons Navarro et al. ONCOLOGY
- Comprehensive Gene and microRNA Expression Profiling Reveals a Role for microRNAs in Human Liver Development
- (2009) Galit Tzur et al. PLoS One
- Let-7a microRNA suppresses therapeutics-induced cancer cell death by targeting caspase-3
- (2008) Wing Pui Tsang et al. APOPTOSIS
- MicroRNA signatures associated with cytogenetics and prognosis in acute myeloid leukemia
- (2008) R. Garzon et al. BLOOD
- MicroRNA Expression Profiling in Human Ovarian Cancer: miR-214 Induces Cell Survival and Cisplatin Resistance by Targeting PTEN
- (2008) H. Yang et al. CANCER RESEARCH
- Genomic Profiling of MicroRNA and Messenger RNA Reveals Deregulated MicroRNA Expression in Prostate Cancer
- (2008) S. Ambs et al. CANCER RESEARCH
- Overlapping expression of microRNAs in human embryonic colon and colorectal cancer
- (2008) Mariano Monzo et al. CELL RESEARCH
- MicroRNA Regulation of Cell Lineages in Mouse and Human Embryonic Stem Cells
- (2008) Kathryn N. Ivey et al. Cell Stem Cell
- Clinical Significance of High Mobility Group A2 in Human Gastric Cancer and Its Relationship to let-7 MicroRNA Family
- (2008) K. Motoyama et al. CLINICAL CANCER RESEARCH
- MicroRNA Expression Profiles in Serous Ovarian Carcinoma
- (2008) E. J. Nam et al. CLINICAL CANCER RESEARCH
- NF-κB and cancer—identifying targets and mechanisms
- (2008) Willscott E Naugler et al. CURRENT OPINION IN GENETICS & DEVELOPMENT
- Drosophila let-7 microRNA is required for remodeling of the neuromusculature during metamorphosis
- (2008) N. S. Sokol et al. GENES & DEVELOPMENT
- Identification of metastasis-related microRNAs in hepatocellular carcinoma
- (2008) Anuradha Budhu et al. HEPATOLOGY
- Lin28 Mediates the Terminal Uridylation of let-7 Precursor MicroRNA
- (2008) Inha Heo et al. MOLECULAR CELL
- A combinatorial library of lipid-like materials for delivery of RNAi therapeutics
- (2008) Akin Akinc et al. NATURE BIOTECHNOLOGY
- A feedback loop comprising lin-28 and let-7 controls pre-let-7 maturation during neural stem-cell commitment
- (2008) Agnieszka Rybak et al. NATURE CELL BIOLOGY
- MicroRNA Expression and Identification of Putative miRNA Targets in Ovarian Cancer
- (2008) Neetu Dahiya et al. PLoS One
- Suppression of non-small cell lung tumor development by the let-7 microRNA family
- (2008) M. S. Kumar et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Expression of microRNAs and protein‐coding genes associated with perineural invasion in prostate cancer
- (2008) Robyn L. Prueitt et al. PROSTATE
- The let-7 family of microRNAs
- (2008) Sarah Roush et al. TRENDS IN CELL BIOLOGY
- let-7 microRNAs in development, stem cells and cancer
- (2008) Ingo Büssing et al. TRENDS IN MOLECULAR MEDICINE
Add your recorded webinar
Do you already have a recorded webinar? Grow your audience and get more views by easily listing your recording on Peeref.
Upload NowAsk a Question. Answer a Question.
Quickly pose questions to the entire community. Debate answers and get clarity on the most important issues facing researchers.
Get Started