Smoothened transduces Hedgehog signal by forming a complex with Evc/Evc2
Published 2012 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Smoothened transduces Hedgehog signal by forming a complex with Evc/Evc2
Authors
Keywords
-
Journal
CELL RESEARCH
Volume 22, Issue 11, Pages 1593-1604
Publisher
Springer Nature
Online
2012-09-18
DOI
10.1038/cr.2012.134
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Distinct Phosphorylations on Kinesin Costal-2 Mediate Differential Hedgehog Signaling Strength
- (2012) Nadia Ranieri et al. DEVELOPMENTAL CELL
- Evc2 is a positive modulator of Hedgehog signalling that interacts with Evc at the cilia membrane and is also found in the nucleus
- (2011) Helen J Blair et al. BMC BIOLOGY
- Evc works in chondrocytes and osteoblasts to regulate multiple aspects of growth plate development in the appendicular skeleton and cranial base
- (2011) María Pacheco et al. BONE
- Transduction of the Hedgehog signal through the dimerization of Fused and the nuclear translocation of Cubitus interruptus
- (2011) Yanyan Zhang et al. CELL RESEARCH
- Kif7 promotes hedgehog signaling in growth plate chondrocytes by restricting the inhibitory function of Sufu
- (2011) S.-H. C. Hsu et al. DEVELOPMENT
- The Hedgehog-induced Smoothened conformational switch assembles a signaling complex that activates Fused by promoting its dimerization and phosphorylation
- (2011) Q. Shi et al. DEVELOPMENT
- Hedgehog Activates Fused through Phosphorylation to Elicit a Full Spectrum of Pathway Responses
- (2011) Qianhe Zhou et al. DEVELOPMENTAL CELL
- Sonic Hedgehog Dependent Phosphorylation by CK1α and GRK2 Is Required for Ciliary Accumulation and Activation of Smoothened
- (2011) Yongbin Chen et al. PLOS BIOLOGY
- The output of Hedgehog signaling is controlled by the dynamic association between Suppressor of Fused and the Gli proteins
- (2010) E. W. Humke et al. GENES & DEVELOPMENT
- G protein-coupled receptor kinase 2 promotes high-level Hedgehog signaling by regulating the active state of Smo through kinase-dependent and kinase-independent mechanisms in Drosophila
- (2010) Y. Chen et al. GENES & DEVELOPMENT
- A mechanism for vertebrate Hedgehog signaling: recruitment to cilia and dissociation of SuFu–Gli protein complexes
- (2010) Hanna Tukachinsky et al. JOURNAL OF CELL BIOLOGY
- The Mammalian Cos2 Homolog Kif7 Plays an Essential Role in Modulating Hh Signal Transduction during Development
- (2009) Setsu Endoh-Yamagami et al. CURRENT BIOLOGY
- Cilium-independent regulation of Gli protein function by Sufu in Hedgehog signaling is evolutionarily conserved
- (2009) M.-H. Chen et al. GENES & DEVELOPMENT
- Widening the mutation spectrum ofEVCandEVC2: ectopic expression of Weyer variants in NIH 3T3 fibroblasts disrupts hedgehog signaling
- (2009) Maria Valencia et al. HUMAN MUTATION
- Mouse Kif7/Costal2 is a cilia-associated protein that regulates Sonic hedgehog signaling
- (2009) K. F. Liem et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Small-molecule inhibitors reveal multiple strategies for Hedgehog pathway blockade
- (2009) J. M. Hyman et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- The Kinesin Protein Kif7 Is a Critical Regulator of Gli Transcription Factors in Mammalian Hedgehog Signaling
- (2009) H. O.-L. Cheung et al. Science Signaling
- Hedgehog Signaling in Development and Cancer
- (2008) Jin Jiang et al. DEVELOPMENTAL CELL
Find Funding. Review Successful Grants.
Explore over 25,000 new funding opportunities and over 6,000,000 successful grants.
ExploreCreate your own webinar
Interested in hosting your own webinar? Check the schedule and propose your idea to the Peeref Content Team.
Create Now