Icariin attenuates hypoxia-induced oxidative stress and apoptosis in osteoblasts and preserves their osteogenic differentiation potentialin vitro

Icariin prevents ovariectomy-induced bone loss and lowers marrow adipogenesis

(2014) Guan-Wu Li et al.   MENOPAUSE-THE JOURNAL OF THE NORTH AMERICAN MENOPAUSE SOCIETY

HIF-1α Confers Resistance to Induced Stress in Bone Marrow-derived Mesenchymal Stem Cells

(2013) Ali Asghar Kiani et al.   ARCHIVES OF MEDICAL RESEARCH

Icariin induces osteoblast proliferation, differentiation and mineralization through estrogen receptor-mediated ERK and JNK signal activation

(2013) Lige Song et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Icaritin attenuates cigarette smoke-mediated oxidative stress in human lung epithelial cells via activation of PI3K-AKT and Nrf2 signaling

(2013) Jinfeng Wu et al.   FOOD AND CHEMICAL TOXICOLOGY

Icariin Protects Rat Cardiac H9c2 Cells from Apoptosis by Inhibiting Endoplasmic Reticulum Stress

(2013) Qiufang Zhang et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Nrf2-dependent upregulation of antioxidative enzymes: a novel pathway for hypoxic preconditioning-mediated delayed cardioprotection

(2013) Xiao-Shan Huang et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

Icariin Induces Osteoblast Differentiation and Mineralization without Dexamethasone in Vitro

(2013) Xiao-Ni Ma et al.   PLANTA MEDICA

Herba epimedii flavonoids suppress osteoclastic differentiation and bone resorption by inducing G2/M arrest and apoptosis

(2012) Dawei Zhang et al.   BIOCHIMIE

Functions and action mechanisms of flavonoids genistein and icariin in regulating bone remodeling

(2012) Lei-Guo Ming et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Cadmium activates a programmed, lysosomal membrane permeabilization-dependent necrosis pathway

(2012) Barbara Messner et al.   TOXICOLOGY LETTERS

Effects of 50Hz sinusoidal electromagnetic fields of different intensities on proliferation, differentiation and mineralization potentials of rat osteoblasts

(2011) Jian Zhou et al.   BONE

Resveratrol promotes osteogenesis of human mesenchymal stem cells by upregulating RUNX2 gene expression via the SIRT1/FOXO3A axis

(2011) Pei-Chi Tseng et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Soft Bone – Hard Arteries: A Link?

(2011) Gérard M. London   KIDNEY & BLOOD PRESSURE RESEARCH

Hard arteries, weak bones

(2011) James F. Griffith et al.   SKELETAL RADIOLOGY

Icariin protects against bone loss induced by oestrogen deficiency and activates oestrogen receptor-dependent osteoblastic functions in UMR 106 cells

(2010) Sao-Keng Mok et al.   BRITISH JOURNAL OF PHARMACOLOGY

Mitochondria and GSK-3β in Cardioprotection Against Ischemia/Reperfusion Injury

(2010) Tetsuji Miura et al.   CARDIOVASCULAR DRUGS AND THERAPY

Reduced local blood supply to the tibial metaphysis is associated with ovariectomy-induced osteoporosis in mice

(2010) Wen-Ge Ding et al.   CONNECTIVE TISSUE RESEARCH

From Estrogen-Centric to Aging and Oxidative Stress: A Revised Perspective of the Pathogenesis of Osteoporosis

(2010) Stavros C. Manolagas   ENDOCRINE REVIEWS

Icariin is more potent than genistein in promoting osteoblast differentiation and mineralization in vitro

(2010) Hui-Ping Ma et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Endogenous glucocorticoids decrease skeletal angiogenesis, vascularity, hydration, and strength in aged mice

(2009) Robert S. Weinstein et al.   AGING CELL

PROTECTIVE EFFECTS OF ICARIIN ON COGNITIVE DEFICITS INDUCED BY CHRONIC CEREBRAL HYPOPERFUSION IN RATS

(2009) Rui-Xia Xu et al.   CLINICAL AND EXPERIMENTAL PHARMACOLOGY AND PHYSIOLOGY

Antiosteoporotic activity of icariin in ovariectomized rats

(2009) H. Nian et al.   PHYTOMEDICINE

Oxygen Sensing by Metazoans: The Central Role of the HIF Hydroxylase Pathway

(2008) William G. Kaelin et al.   MOLECULAR CELL