Gene polymorphisms of cellular senescence marker p21 and disease progression in non-alcohol-related fatty liver disease

Progression of NAFLD to diabetes mellitus, cardiovascular disease or cirrhosis

(2013) Quentin M. Anstee et al.   Nature Reviews Gastroenterology & Hepatology

Hepatocyte Expression of the Senescence Marker p21 Is Linked to Fibrosis and an Adverse Liver-Related Outcome in Alcohol-Related Liver Disease

(2013) Aloysious Aravinthan et al.   PLoS One

Interleukin-22 induces hepatic stellate cell senescence and restricts liver fibrosis in mice

(2012) Xiaoni Kong et al.   HEPATOLOGY

p53/p66Shc-mediated signaling contributes to the progression of non-alcoholic steatohepatitis in humans and mice

(2012) Kengo Tomita et al.   JOURNAL OF HEPATOLOGY

Hepatocyte senescence predicts progression in non-alcohol-related fatty liver disease

(2012) Aloysious Aravinthan et al.   JOURNAL OF HEPATOLOGY

Atorvastatin inhibits proliferation and apoptosis, but induces senescence in hepatic myofibroblasts and thereby attenuates hepatic fibrosis in rats

(2012) Sabine Klein et al.   LABORATORY INVESTIGATION

Association between Variations in Cell Cycle Genes and Idiopathic Pulmonary Fibrosis

(2012) Nicoline M. Korthagen et al.   PLoS One

The SOD2 C47T polymorphism influences NAFLD fibrosis severity: Evidence from case-control and intra-familial allele association studies

(2011) Ahmad Al-Serri et al.   JOURNAL OF HEPATOLOGY

Genetics of Alcoholic and Nonalcoholic Fatty Liver Disease

(2011) Quentin Anstee et al.   SEMINARS IN LIVER DISEASE

Bile Ductular Cells Undergoing Cellular Senescence Increase in Chronic Liver Diseases Along With Fibrous Progression

(2010) Motoko Sasaki et al.   AMERICAN JOURNAL OF CLINICAL PATHOLOGY

Senescent cells as a source of inflammatory factors for tumor progression

(2010) Albert R. Davalos et al.   CANCER AND METASTASIS REVIEWS

Genome-Wide Association Study Identifies Variants Associated With Histologic Features of Nonalcoholic Fatty Liver Disease

(2010) Naga Chalasani et al.   GASTROENTEROLOGY

Genetic variants regulating insulin receptor signalling are associated with the severity of liver damage in patients with non-alcoholic fatty liver disease

(2010) P. Dongiovanni et al.   GUT

The association of genetic variability in patatin-like phospholipase domain-containing protein 3 (PNPLA3) with histological severity of nonalcoholic fatty liver disease

(2010) Yaron Rotman et al.   HEPATOLOGY

Homozygosity for the patatin-like phospholipase-3/adiponutrin I148M polymorphism influences liver fibrosis in patients with nonalcoholic fatty liver disease

(2010) Luca Valenti et al.   HEPATOLOGY

Potentially functional polymorphisms in cell cycle genes and the survival of non-small cell lung cancer in a Chinese population

(2010) Hongxia Ma et al.   LUNG CANCER

Nuclear size measurement is a simple method for the assessment of hepatocellular aging in non-alcoholic fatty liver disease: Comparison with telomere-specific quantitative FISH and p21 immunohistochemistry

(2010) Tomoki Nakajima et al.   PATHOLOGY INTERNATIONAL

Association between angiotensin II type 1 receptor polymorphisms and the occurrence of nonalcoholic fatty liver disease

(2009) Masato Yoneda et al.   LIVER INTERNATIONAL

Senescence of Activated Stellate Cells Limits Liver Fibrosis

(2008) Valery Krizhanovsky et al.   CELL

The Kruppel-Like Factor 6 Genotype Is Associated With Fibrosis in Nonalcoholic Fatty Liver Disease

(2008) Luca Miele et al.   GASTROENTEROLOGY

Telomere shortening in the damaged small bile ducts in primary biliary cirrhosis reflects ongoing cellular senescence

(2008) Motoko Sasaki et al.   HEPATOLOGY

Non-alcoholic fatty liver disease: The mist gradually clears

(2008) Nimantha Mark Wilfred de Alwis et al.   JOURNAL OF HEPATOLOGY

The Epidemiology of Nonalcoholic Fatty Liver Disease: A Global Perspective

(2008) Mariana Lazo et al.   SEMINARS IN LIVER DISEASE