Bioenergetic properties of human sarcoma cells help define sensitivity to metabolic inhibitors

Mitochondria-Targeted Drugs Synergize with 2-Deoxyglucose to Trigger Breast Cancer Cell Death

(2012) G. Cheng et al.   CANCER RESEARCH

New targets and approaches in osteosarcoma

(2012) Jonathan Gill et al.   PHARMACOLOGY & THERAPEUTICS

Cellular bioenergetics is regulated by PARP1 under resting conditions and during oxidative stress

(2011) Katalin Módis et al.   BIOCHEMICAL PHARMACOLOGY

2-Deoxyglucose Induces Noxa-Dependent Apoptosis in Alveolar Rhabdomyosarcoma

(2011) S. Ramirez-Peinado et al.   CANCER RESEARCH

Hallmarks of Cancer: The Next Generation

(2011) Douglas Hanahan et al.   CELL

Glycolysis inhibition by 2-deoxy-d-glucose reverts the metastatic phenotype in vitro and in vivo

(2011) Joseph L. Sottnik et al.   CLINICAL & EXPERIMENTAL METASTASIS

Inhibition of the Notch-Hey1 Axis Blocks Embryonal Rhabdomyosarcoma Tumorigenesis

(2011) B. C. Belyea et al.   CLINICAL CANCER RESEARCH

Assessing bioenergetic function in response to oxidative stress by metabolic profiling

(2011) Brian P. Dranka et al.   FREE RADICAL BIOLOGY AND MEDICINE

Dual Inhibition of Tumor Energy Pathway by 2-Deoxyglucose and Metformin Is Effective against a Broad Spectrum of Preclinical Cancer Models

(2011) J.-H. Cheong et al.   MOLECULAR CANCER THERAPEUTICS

Targeting cancer metabolism: a therapeutic window opens

(2011) Matthew G. Vander Heiden   NATURE REVIEWS DRUG DISCOVERY

Targeting Cancer Cell Metabolism: The Combination of Metformin and 2-Deoxyglucose Induces p53-Dependent Apoptosis in Prostate Cancer Cells

(2010) I. Ben Sahra et al.   CANCER RESEARCH

Bioenergetic function in cardiovascular cells: The importance of the reserve capacity and its biological regulation

(2010) Brian E. Sansbury et al.   CHEMICO-BIOLOGICAL INTERACTIONS

Mitochondrial reserve capacity in endothelial cells: The impact of nitric oxide and reactive oxygen species

(2010) Brian P. Dranka et al.   FREE RADICAL BIOLOGY AND MEDICINE

Importance of the bioenergetic reserve capacity in response to cardiomyocyte stress induced by 4-hydroxynonenal

(2009) Bradford G. Hill et al.   BIOCHEMICAL JOURNAL

Understanding the Warburg Effect: The Metabolic Requirements of Cell Proliferation

(2009) M. G. Vander Heiden et al.   SCIENCE

Experimental assessment of bioenergetic differences caused by the common European mitochondrial DNA haplogroups H and T

(2008) Taku Amo et al.   GENE