Metabolome and metaboproteome remodeling in nuclear reprogramming

Mitochondrial fusion by pharmacological manipulation impedes somatic cell reprogramming to pluripotency: New insight into the role of mitophagy in cell stemness

(2016) Alejandro Vazquez-Martin et al.   Aging-US

The mitochondrial H+-ATP synthase and the lipogenic switch

(2013) Alejandro Vazquez-Martin et al.   CELL CYCLE

Energy metabolism plasticity enables stemness programs

(2012) Clifford D.L. Folmes et al.   Annals of the New York Academy of Sciences

Reprogramming Cellular Identity for Regenerative Medicine

(2012) Anne B.C. Cherry et al.   CELL

The expanding role of miR-302–367 in pluripotency and reprogramming

(2012) Inna Lipchina et al.   CELL CYCLE

Activation of AMP-activated protein kinase (AMPK) provides a metabolic barrier to reprogramming somatic cells into stem cells

(2012) Alejandro Vazquez-Martin et al.   CELL CYCLE

Metabolic Regulation in Pluripotent Stem Cells during Reprogramming and Self-Renewal

(2012) Jin Zhang et al.   Cell Stem Cell

Metabolic Plasticity in Stem Cell Homeostasis and Differentiation

(2012) Clifford D.L. Folmes et al.   Cell Stem Cell

Systems Proteomics for Translational Network Medicine

(2012) D. Kent Arrell et al.   Circulation-Cardiovascular Genetics

Measuring energy metabolism in cultured cells, including human pluripotent stem cells and differentiated cells

(2012) Jin Zhang et al.   Nature Protocols

Metabolomics: the apogee of the omics trilogy

(2012) Gary J. Patti et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Influence of Threonine Metabolism on S-Adenosylmethionine and Histone Methylation

(2012) N. Shyh-Chang et al.   SCIENCE

Highly Coordinated Proteome Dynamics during Reprogramming of Somatic Cells to Pluripotency

(2012) Jenny Hansson et al.   Cell Reports

Energy metabolism in nuclear reprogramming

(2011) Clifford DL Folmes et al.   Biomarkers in Medicine

mTOR-regulated senescence and autophagy during reprogramming of somatic cells to pluripotency: A roadmap from energy metabolism to stem cell renewal and aging

(2011) Javier A. Menendez et al.   CELL CYCLE

Ketones and lactate increase cancer cell “stemness,” driving recurrence, metastasis and poor clinical outcome in breast cancer

(2011) Ubaldo E. Martinez-Outschoorn et al.   CELL CYCLE

Anaerobicizing into Pluripotency

(2011) Athanasia D. Panopoulos et al.   Cell Metabolism

Somatic Oxidative Bioenergetics Transitions into Pluripotency-Dependent Glycolysis to Facilitate Nuclear Reprogramming

(2011) Clifford D.L. Folmes et al.   Cell Metabolism

The metabolome of induced pluripotent stem cells reveals metabolic changes occurring in somatic cell reprogramming

(2011) Athanasia D Panopoulos et al.   CELL RESEARCH

miR-371-3 Expression Predicts Neural Differentiation Propensity in Human Pluripotent Stem Cells

(2011) Hyesoo Kim et al.   Cell Stem Cell

Disease Correction the iPSC Way: Advances in iPSC-Based Therapy

(2011) I Sancho-Martinez et al.   CLINICAL PHARMACOLOGY & THERAPEUTICS

iPSC Technology: Platform for Drug Discovery

(2011) J Ellis et al.   CLINICAL PHARMACOLOGY & THERAPEUTICS

Induced Pluripotent Stem Cells: An Emerging Theranostics Platform

(2011) T J Nelson et al.   CLINICAL PHARMACOLOGY & THERAPEUTICS

The Use of Induced Pluripotent Stem Cells in Drug Development

(2011) H Inoue et al.   CLINICAL PHARMACOLOGY & THERAPEUTICS

UCP2 regulates energy metabolism and differentiation potential of human pluripotent stem cells

(2011) Jin Zhang et al.   EMBO JOURNAL

Human pluripotent stem cells decouple respiration from energy production

(2011) Ng Shyh-Chang et al.   EMBO JOURNAL

Genome-wide identification of microRNA targets in human ES cells reveals a role for miR-302 in modulating BMP response

(2011) I. Lipchina et al.   GENES & DEVELOPMENT

Modulation of mitochondrial biogenesis and bioenergetic metabolism upon in vitro and in vivo differentiation of human ES and iPS cells

(2011) Alessandro Prigione et al.   INTERNATIONAL JOURNAL OF DEVELOPMENTAL BIOLOGY

Multiple targets of miR-302 and miR-372 promote reprogramming of human fibroblasts to induced pluripotent stem cells

(2011) Deepa Subramanyam et al.   NATURE BIOTECHNOLOGY

Energy Metabolism in Human Pluripotent Stem Cells and Their Differentiated Counterparts

(2011) Sandra Varum et al.   PLoS One

Reprogramming of Human Primary Somatic Cells by OCT4 and Chemical Compounds

(2010) Saiyong Zhu et al.   Cell Stem Cell

Oxygen in Stem Cell Biology: A Critical Component of the Stem Cell Niche

(2010) Ahmed Mohyeldin et al.   Cell Stem Cell

Mitochondrial Rejuvenation After Induced Pluripotency

(2010) Steven T. Suhr et al.   PLoS One

The Senescence-Related Mitochondrial/Oxidative Stress Pathway is Repressed in Human Induced Pluripotent Stem Cells

(2010) Alessandro Prigione et al.   STEM CELLS

Human Induced Pluripotent Stem Cell Lines Show Stress Defense Mechanisms and Mitochondrial Regulation Similar to Those of Human Embryonic Stem Cells

(2010) Lyle Armstrong et al.   STEM CELLS

ATP-Sensitive K+ Channel-Deficient Dilated Cardiomyopathy Proteome Remodeled by Embryonic Stem Cell Therapy

(2010) Jelena Zlatkovic-Lindor et al.   STEM CELLS

Hypoxia Enhances the Generation of Induced Pluripotent Stem Cells

(2009) Yoshinori Yoshida et al.   Cell Stem Cell

Alternative Induced Pluripotent Stem Cell Characterization Criteria for In Vitro Applications

(2009) James Ellis et al.   Cell Stem Cell

Broader Implications of Defining Standards for the Pluripotency of iPSCs

(2009) George Q. Daley et al.   Cell Stem Cell

Repair of Acute Myocardial Infarction by Human Stemness Factors Induced Pluripotent Stem Cells

(2009) Timothy J. Nelson et al.   CIRCULATION

Senescence impairs successful reprogramming to pluripotent stem cells

(2009) A. Banito et al.   GENES & DEVELOPMENT

Pluripotency: Toward a gold standard for human ES and iPS cells

(2009) Kelly P. Smith et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Linking the p53 tumour suppressor pathway to somatic cell reprogramming

(2009) Teruhisa Kawamura et al.   NATURE

A p53-mediated DNA damage response limits reprogramming to ensure iPS cell genomic integrity

(2009) Rosa M. Marión et al.   NATURE

Suppression of induced pluripotent stem cell generation by the p53–p21 pathway

(2009) Hyenjong Hong et al.   NATURE

The Ink4/Arf locus is a barrier for iPS cell reprogramming

(2009) Han Li et al.   NATURE

Phenotypic correction of murine hemophilia A using an iPS cell-based therapy

(2009) Dan Xu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Induced Pluripotent Stem Cells at Nanoscale

(2009) Dagmar Zeuschner et al.   STEM CELLS AND DEVELOPMENT

Effects of oxygen on mouse embryonic stem cell growth, phenotype retention, and cellular energetics

(2008) Daryl E. Powers et al.   BIOTECHNOLOGY AND BIOENGINEERING

Guidelines and Techniques for the Generation of Induced Pluripotent Stem Cells

(2008) Nimet Maherali et al.   Cell Stem Cell

Neurons derived from reprogrammed fibroblasts functionally integrate into the fetal brain and improve symptoms of rats with Parkinson's disease

(2008) M. Wernig et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Coordinated Changes of Mitochondrial Biogenesis and Antioxidant Enzymes During Osteogenic Differentiation of Human Mesenchymal Stem Cells

(2008) Chien-Tsun Chen et al.   STEM CELLS

Identification of Oxygen-Sensitive Transcriptional Programs in Human Embryonic Stem Cells

(2008) Suzanne D. Westfall et al.   STEM CELLS AND DEVELOPMENT

Cardioinductive Network Guiding Stem Cell Differentiation Revealed by Proteomic Cartography of Tumor Necrosis Factor α-Primed Endodermal Secretome

(2007) D. Kent Arrell et al.   STEM CELLS