EGFR signaling and autophagy dependence for growth, survival, and therapy resistance
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Title
EGFR signaling and autophagy dependence for growth, survival, and therapy resistance
Authors
Keywords
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Journal
CELL CYCLE
Volume 13, Issue 1, Pages 42-51
Publisher
Informa UK Limited
Online
2013-12-19
DOI
10.4161/cc.27518
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Note: Only part of the references are listed.- Expression of EGFRvIII in Glioblastoma: Prognostic Significance Revisited
- (2015) Nicola Montano et al. NEOPLASIA
- Activation of Multiple ERBB Family Receptors Mediates Glioblastoma Cancer Stem-like Cell Resistance to EGFR-Targeted Inhibition
- (2015) Paul A. Clark et al. NEOPLASIA
- Autophagy inhibition induces enhanced proapoptotic effects of ZD6474 in glioblastoma
- (2013) J Shen et al. BRITISH JOURNAL OF CANCER
- EGFR-Mediated Beclin 1 Phosphorylation in Autophagy Suppression, Tumor Progression, and Tumor Chemoresistance
- (2013) Yongjie Wei et al. CELL
- EGFR Mutation-Induced Alternative Splicing of Max Contributes to Growth of Glycolytic Tumors in Brain Cancer
- (2013) Ivan Babic et al. Cell Metabolism
- A Minority Subpopulation of CD133+/EGFRvIII+/EGFR−Cells Acquires Stemness and Contributes to Gefitinib Resistance
- (2013) Xu-Jie Liu et al. CNS Neuroscience & Therapeutics
- Cancer stem-like cell properties are regulated by EGFR/AKT/β-catenin signaling and preferentially inhibited by gefitinib in nasopharyngeal carcinoma
- (2013) Lei Ma et al. FEBS Journal
- The Autophagy Inhibitor Chloroquine Overcomes the Innate Resistance of Wild-Type EGFR Non-Small-Cell Lung Cancer Cells to Erlotinib
- (2013) Yiyu Zou et al. Journal of Thoracic Oncology
- Erlotinib-induced autophagy in epidermal growth factor receptor mutated non-small cell lung cancer
- (2013) Yuan-yuan Li et al. LUNG CANCER
- PERK/eIF2 signaling protects therapy resistant hypoxic cells through induction of glutathione synthesis and protection against ROS
- (2013) K. M. Rouschop et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Predictive value of hypoxia, proliferation and tyrosine kinase receptors for EGFR-inhibition and radiotherapy sensitivity in head and neck cancer models
- (2013) Hanneke Stegeman et al. RADIOTHERAPY AND ONCOLOGY
- EGFR overexpressing cells and tumors are dependent on autophagy for growth and survival
- (2013) Barry Jutten et al. RADIOTHERAPY AND ONCOLOGY
- The autophagy associated gene, ULK1, promotes tolerance to chronic and acute hypoxia
- (2013) Marco B.E. Schaaf et al. RADIOTHERAPY AND ONCOLOGY
- Mcl-1-dependent activation of Beclin 1 mediates autophagic cell death induced by sorafenib and SC-59 in hepatocellular carcinoma cells
- (2013) W-T Tai et al. Cell Death & Disease
- A view on EGFR-targeted therapies from the oncogene-addiction perspective
- (2013) Rolando Perez et al. Frontiers in Pharmacology
- Direct interaction between STAT3 and EIF2AK2 controls fatty acid-induced autophagy
- (2012) Mireia Niso-Santano et al. Autophagy
- Transcriptional up-regulation of ULK1 by ATF4 contributes to cancer cell survival
- (2012) Luke R. G. Pike et al. BIOCHEMICAL JOURNAL
- Epidermal Growth Factor Receptor Variant III Contributes to Cancer Stem Cell Phenotypes in Invasive Breast Carcinoma
- (2012) C. A. Del Vecchio et al. CANCER RESEARCH
- Expression of epidermal growth factor variant III (EGFRvIII) in pediatric diffuse intrinsic pontine gliomas
- (2012) Gordon Li et al. JOURNAL OF NEURO-ONCOLOGY
- Cytoplasmic STAT3 Represses Autophagy by Inhibiting PKR Activity
- (2012) Shensi Shen et al. MOLECULAR CELL
- The autophagy-associated factors DRAM1 and p62 regulate cell migration and invasion in glioblastoma stem cells
- (2012) S Galavotti et al. ONCOGENE
- Beclin 1 and autophagy are required for the tumorigenicity of breast cancer stem-like/progenitor cells
- (2012) C Gong et al. ONCOGENE
- ULK1 inhibits the kinase activity of mTORC1 and cell proliferation
- (2011) Chang Hwa Jung et al. Autophagy
- Molecular mechanisms of resistance to the EGFR monoclonal antibody cetuximab
- (2011) Toni M. Brand et al. CANCER BIOLOGY & THERAPY
- Maintenance of EGFR and EGFRvIII expressions in an in vivo and in vitro model of human glioblastoma multiforme
- (2011) Marie-Thérése Stockhausen et al. EXPERIMENTAL CELL RESEARCH
- Activated Ras requires autophagy to maintain oxidative metabolism and tumorigenesis
- (2011) J. Y. Guo et al. GENES & DEVELOPMENT
- Involvement of Autophagy in Oncogenic K-Ras-induced Malignant Cell Transformation
- (2011) Min-Jung Kim et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Activation of Src induces mitochondrial localisation of de2-7EGFR (EGFRvIII) in glioma cells: implications for glucose metabolism
- (2011) Anna N. Cvrljevic et al. JOURNAL OF CELL SCIENCE
- EGFR exon 20 insertion mutations in non-small-cell lung cancer: preclinical data and clinical implications
- (2011) Hiroyuki Yasuda et al. LANCET ONCOLOGY
- Role of AMPK-mTOR-Ulk1/2 in the Regulation of Autophagy: Cross Talk, Shortcuts, and Feedbacks
- (2011) S. Alers et al. MOLECULAR AND CELLULAR BIOLOGY
- EGFR and EGFRvIII undergo stress- and EGFR kinase inhibitor-induced mitochondrial translocalization: A potential mechanism of EGFR-driven antagonism of apoptosis
- (2011) Xinyu Cao et al. Molecular Cancer
- AMPK and mTOR regulate autophagy through direct phosphorylation of Ulk1
- (2011) Joungmok Kim et al. NATURE CELL BIOLOGY
- EGFR Tyrosine Kinase Inhibitors Activate Autophagy as a Cytoprotective Response in Human Lung Cancer Cells
- (2011) Weidong Han et al. PLoS One
- Deregulation of cap-dependent mRNA translation increases tumour radiosensitivity through reduction of the hypoxic fraction
- (2011) Kasper M.A. Rouschop et al. RADIOTHERAPY AND ONCOLOGY
- Hypoxic modification of radiotherapy in squamous cell carcinoma of the head and neck – A systematic review and meta-analysis
- (2011) Jens Overgaard RADIOTHERAPY AND ONCOLOGY
- Roles of autophagy in cetuximab-mediated cancer therapy against EGFR
- (2010) Xinqun Li et al. Autophagy
- Pro-survival AKT and ERK signaling from EGFR and mutant EGFRvIII enhances DNA double-strand break repair in human glioma cells
- (2010) Sarah E. Golding et al. CANCER BIOLOGY & THERAPY
- Epidermal Growth Factor Receptor Expression Identifies Functionally and Molecularly Distinct Tumor-Initiating Cells in Human Glioblastoma Multiforme and Is Required for Gliomagenesis
- (2010) S. Mazzoleni et al. CANCER RESEARCH
- The Epidermal Growth Factor Receptor Antibody Cetuximab Induces Autophagy in Cancer Cells by Downregulating HIF-1 and Bcl-2 and Activating the Beclin 1/hVps34 Complex
- (2010) X. Li et al. CANCER RESEARCH
- Nuclear EGFR shuttling induced by ionizing radiation is regulated by phosphorylation at residue Thr654
- (2010) Klaus Dittmann et al. FEBS LETTERS
- Autophagy facilitates glycolysis during Ras-mediated oncogenic transformation
- (2010) Rebecca Lock et al. MOLECULAR BIOLOGY OF THE CELL
- Different Response of Human Glioma Tumor-initiating Cells to Epidermal Growth Factor Receptor Kinase Inhibitors
- (2009) Fabrizio Griffero et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Epidermal Growth Factor Receptor Translocation to the Mitochondria
- (2009) Michelle L. Demory et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- The unfolded protein response protects human tumor cells during hypoxia through regulation of the autophagy genes MAP1LC3B and ATG5
- (2009) Kasper M.A. Rouschop et al. JOURNAL OF CLINICAL INVESTIGATION
- The EGFRvIII variant in glioblastoma multiforme
- (2009) Hui K. Gan et al. JOURNAL OF CLINICAL NEUROSCIENCE
- Different molecular patterns in glioblastoma multiforme subtypes upon recurrence
- (2009) Ramon Martinez et al. JOURNAL OF NEURO-ONCOLOGY
- Hypoxia-Induced Autophagy Is Mediated through Hypoxia-Inducible Factor Induction of BNIP3 and BNIP3L via Their BH3 Domains
- (2009) G. Bellot et al. MOLECULAR AND CELLULAR BIOLOGY
- Nutrient-dependent mTORC1 Association with the ULK1–Atg13–FIP200 Complex Required for Autophagy
- (2009) Nao Hosokawa et al. MOLECULAR BIOLOGY OF THE CELL
- Two Beclin 1-binding proteins, Atg14L and Rubicon, reciprocally regulate autophagy at different stages
- (2009) Kohichi Matsunaga et al. NATURE CELL BIOLOGY
- The AMPK agonist AICAR inhibits the growth of EGFRvIII-expressing glioblastomas by inhibiting lipogenesis
- (2009) D. Guo et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- The deletion mutant EGFRvIII significantly contributes to stress resistance typical for the tumour microenvironment
- (2009) Jan Theys et al. RADIOTHERAPY AND ONCOLOGY
- Autophagy is required during cycling hypoxia to lower production of reactive oxygen species
- (2009) Kasper M.A. Rouschop et al. RADIOTHERAPY AND ONCOLOGY
- Proliferation of Human Glioblastoma Stem Cells Occurs Independently of Exogenous Mitogens
- (2009) John J. P. Kelly et al. STEM CELLS
- Crystal structure of unphosphorylated STAT3 core fragment
- (2008) Zhiyong Ren et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Survival of Cancer Cells Is Maintained by EGFR Independent of Its Kinase Activity
- (2008) Zhang Weihua et al. CANCER CELL
- Oncogene Addiction
- (2008) I. B. Weinstein et al. CANCER RESEARCH
- Hypoxia signals autophagy in tumor cells via AMPK activity, independent of HIF-1, BNIP3 and BNIP3L
- (2008) I Papandreou et al. CELL DEATH AND DIFFERENTIATION
- Epidermal Growth Factor Plays a Crucial Role in Mitogenic Regulation of Human Brain Tumor Stem Cells
- (2008) Akio Soeda et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Mitochondrial Autophagy Is an HIF-1-dependent Adaptive Metabolic Response to Hypoxia
- (2008) Huafeng Zhang et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Beclin 1 Forms Two Distinct Phosphatidylinositol 3-Kinase Complexes with Mammalian Atg14 and UVRAG
- (2008) Eisuke Itakura et al. MOLECULAR BIOLOGY OF THE CELL
- The T790M mutation in EGFR kinase causes drug resistance by increasing the affinity for ATP
- (2008) C.-H. Yun et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- EGFR Tyrosine Kinase Inhibitors in Lung Cancer: An Evolving Story
- (2007) Lecia V. Sequist et al. Annual Review of Medicine
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