microRNA-mediated regulation of the tumor microenvironment

BM mesenchymal stromal cell–derived exosomes facilitate multiple myeloma progression

(2013) Aldo M. Roccaro et al.   JOURNAL OF CLINICAL INVESTIGATION

The Downregulation of microRNA let-7a Contributes to the Excessive Expression of Type I Collagen in Systemic and Localized Scleroderma

(2013) K. Makino et al.   JOURNAL OF IMMUNOLOGY

GATA3 suppresses metastasis and modulates the tumour microenvironment by regulating microRNA-29b expression

(2013) Jonathan Chou et al.   NATURE CELL BIOLOGY

miR-126 and miR-126* repress recruitment of mesenchymal stem cells and inflammatory monocytes to inhibit breast cancer metastasis

(2013) Yun Zhang et al.   NATURE CELL BIOLOGY

MicroRNA-132 is frequently down-regulated in ductal carcinoma in situ (DCIS) of breast and acts as a tumor suppressor by inhibiting cell proliferation

(2013) Shuai Li et al.   PATHOLOGY RESEARCH AND PRACTICE

Class II HDAC Inhibition Hampers Hepatic Stellate Cell Activation by Induction of MicroRNA-29

(2013) Inge Mannaerts et al.   PLoS One

MicroRNA-mediated control of macrophages and its implications for cancer

(2013) Mario Leonardo Squadrito et al.   TRENDS IN IMMUNOLOGY

Upregulation of a Disintegrin and Metalloproteinase With Thrombospondin Motifs-7 by miR-29 Repression Mediates Vascular Smooth Muscle Calcification

(2012) Yaoyao Du et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

miR-155 regulates IFN-  production in natural killer cells

(2012) R. Trotta et al.   BLOOD

Loss of miR-133a expression associated with poor survival of breast cancer and restoration of miR-133a expression inhibited breast cancer cell growth and invasion

(2012) Zheng-sheng Wu et al.   BMC CANCER

Accessories to the Crime: Functions of Cells Recruited to the Tumor Microenvironment

(2012) Douglas Hanahan et al.   CANCER CELL

CCR5 Antagonist Blocks Metastasis of Basal Breast Cancer Cells

(2012) M. Velasco-Velazquez et al.   CANCER RESEARCH

A novel role of hematopoietic CCL5 in promoting triple-negative mammary tumor progression by regulating generation of myeloid-derived suppressor cells

(2012) Yan Zhang et al.   CELL RESEARCH

Prognostic value of miR-29a expression in pediatric acute myeloid leukemia

(2012) Conglong Zhu et al.   CLINICAL BIOCHEMISTRY

microRNA-29b contributes to pre-eclampsia through its effects on apoptosis, invasion and angiogenesis of trophoblast cells

(2012) Pengfei Li et al.   CLINICAL SCIENCE

miR-221 Is Required for Endothelial Tip Cell Behaviors during Vascular Development

(2012) Stefania Nicoli et al.   DEVELOPMENTAL CELL

Induction of Bv8 Expression by Granulocyte Colony-stimulating Factor in CD11b+Gr1+Cells

(2012) Xueping Qu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

MicroRNA-125b Down-regulates Matrix Metallopeptidase 13 and Inhibits Cutaneous Squamous Cell Carcinoma Cell Proliferation, Migration, and Invasion

(2012) Ning Xu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

MicroRNA-155 promotes atherosclerosis by repressing Bcl6 in macrophages

(2012) Maliheh Nazari-Jahantigh et al.   JOURNAL OF CLINICAL INVESTIGATION

microRNA-9 Targets Matrix Metalloproteinase 14 to Inhibit Invasion, Metastasis, and Angiogenesis of Neuroblastoma Cells

(2012) H. Zhang et al.   MOLECULAR CANCER THERAPEUTICS

The microcosmos of cancer

(2012) Amaia Lujambio et al.   NATURE

Melanoma exosomes educate bone marrow progenitor cells toward a pro-metastatic phenotype through MET

(2012) Héctor Peinado et al.   NATURE MEDICINE

DNA methylation silences miR-132 in prostate cancer

(2012) A Formosa et al.   ONCOGENE

Silencing of miR-148a in cancer-associated fibroblasts results in WNT10B-mediated stimulation of tumor cell motility

(2012) O Aprelikova et al.   ONCOGENE

Progestin suppression of miR-29 potentiates dedifferentiation of breast cancer cells via KLF4

(2012) D M Cittelly et al.   ONCOGENE

let-7b and miR-126 Are Down-Regulated in Tumor Tissue and Correlate with Microvessel Density and Survival Outcomes in Non–Small–Cell Lung Cancer

(2012) Edin Jusufović et al.   PLoS One

ECM microenvironment regulates collective migration and local dissemination in normal and malignant mammary epithelium

(2012) K.-V. Nguyen-Ngoc et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

CD49f Enhances Multipotency and Maintains Stemness Through the Direct Regulation of OCT4 and SOX2

(2012) Kyung-Rok Yu et al.   STEM CELLS

Autocrine CCL5 Signaling Promotes Invasion and Migration of CD133+Ovarian Cancer Stem-Like Cells via NF-κB-Mediated MMP-9 Upregulation

(2012) Haixia Long et al.   STEM CELLS

A microRNA network regulates proliferative timing and extracellular matrix synthesis during cellular quiescence in fibroblasts

(2012) Eric J Suh et al.   GENOME BIOLOGY

Dysregulated microRNAs affect pathways and targets of biologic relevance in nasal-type natural killer/T-cell lymphoma

(2011) S.-B. Ng et al.   BLOOD

LOXL2-Mediated Matrix Remodeling in Metastasis and Mammary Gland Involution

(2011) H. E. Barker et al.   CANCER RESEARCH

Downregulation of miR-132 by promoter methylation contributes to pancreatic cancer development

(2011) Shuyu Zhang et al.   CARCINOGENESIS

Lysyl oxidase-like 2 (LOXL2), a new regulator of cell polarity required for metastatic dissemination of basal-like breast carcinomas

(2011) Gema Moreno-Bueno et al.   EMBO Molecular Medicine

Downregulation of microRNA-29c is associated with hypermethylation of tumor-related genes and disease outcome in cutaneous melanoma

(2011) Tung Nguyen et al.   Epigenetics

Macrophages and cathepsin proteases blunt chemotherapeutic response in breast cancer

(2011) T. Shree et al.   GENES & DEVELOPMENT

MicroRNA-29b suppresses tumor angiogenesis, invasion, and metastasis by regulating matrix metalloproteinase 2 expression

(2011) Jian-Hong Fang et al.   HEPATOLOGY

APOBEC3G promotes liver metastasis in an orthotopic mouse model of colorectal cancer and predicts human hepatic metastasis

(2011) Qingqing Ding et al.   JOURNAL OF CLINICAL INVESTIGATION

miR-150 regulates the development of NK and iNKT cells

(2011) Natalie A. Bezman et al.   JOURNAL OF EXPERIMENTAL MEDICINE

MicroRNA-125b Potentiates Macrophage Activation

(2011) Aadel A. Chaudhuri et al.   JOURNAL OF IMMUNOLOGY

Megakaryocytes, malignancy and bone marrow vascular niches

(2011) B. PSAILA et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

Microvesicles secreted by macrophages shuttle invasion-potentiating microRNAs into breast cancer cells

(2011) Mei Yang et al.   Molecular Cancer

A microRNA regulon that mediates endothelial recruitment and metastasis by cancer cells

(2011) Kim J. Png et al.   NATURE

Tumour-infiltrating regulatory T cells stimulate mammary cancer metastasis through RANKL–RANK signalling

(2011) Wei Tan et al.   NATURE

Reprogramming of the tumour microenvironment by stromal PTEN-regulated miR-320

(2011) A. Bronisz et al.   NATURE CELL BIOLOGY

Postpartum mammary gland involution drives progression of ductal carcinoma in situ through collagen and COX-2

(2011) Traci R Lyons et al.   NATURE MEDICINE

Breast cancer cells produce tenascin C as a metastatic niche component to colonize the lungs

(2011) Thordur Oskarsson et al.   NATURE MEDICINE

CD49f and CD61 identify Her2/neu-induced mammary tumor-initiating cells that are potentially derived from luminal progenitors and maintained by the integrin–TGFβ signaling

(2011) P-K Lo et al.   ONCOGENE

Control of tumor and microenvironment cross-talk by miR-15a and miR-16 in prostate cancer

(2011) M Musumeci et al.   ONCOGENE

miRNA-mRNA Integrated Analysis Reveals Roles for miRNAs in Primary Breast Tumors

(2011) Espen Enerly et al.   PLoS One

MicroRNA-29, a key regulator of collagen expression in systemic sclerosis

(2010) Britta Maurer et al.   ARTHRITIS AND RHEUMATISM

Cancer-Associated Fibroblasts Are Activated in Incipient Neoplasia to Orchestrate Tumor-Promoting Inflammation in an NF-κB-Dependent Manner

(2010) Neta Erez et al.   CANCER CELL

Concurrent Suppression of Integrin α5, Radixin, and RhoA Phenocopies the Effects of miR-31 on Metastasis

(2010) Scott Valastyan et al.   CANCER RESEARCH

Matrix Metalloproteinases: Regulators of the Tumor Microenvironment

(2010) Kai Kessenbrock et al.   CELL

Immunity, Inflammation, and Cancer

(2010) Sergei I. Grivennikov et al.   CELL

The role of miR-31 and its target gene SATB2 in cancer-associated fibroblasts

(2010) Olga Aprelikova et al.   CELL CYCLE

MicroRNA-124 suppresses oral squamous cell carcinoma motility by targeting ITGB1

(2010) Stuart Hunt et al.   FEBS LETTERS

Renal Medullary MicroRNAs in Dahl Salt-Sensitive Rats

(2010) Yong Liu et al.   HYPERTENSION

The Interleukin 13 (IL-13) Pathway in Human Macrophages Is Modulated by MicroRNA-155 via Direct Targeting of Interleukin 13 Receptor α1 (IL13Rα1)

(2010) Rocio T. Martinez-Nunez et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Let-7g targets collagen type I α2 and inhibits cell migration in hepatocellular carcinoma

(2010) Junfang Ji et al.   JOURNAL OF HEPATOLOGY

miR-212 and miR-132 are required for epithelial stromal interactions necessary for mouse mammary gland development

(2010) Ahmet Ucar et al.   NATURE GENETICS

Allosteric inhibition of lysyl oxidase–like-2 impedes the development of a pathologic microenvironment

(2010) Vivian Barry-Hamilton et al.   NATURE MEDICINE

Collagen regulation of let-7 in pancreatic cancer involves TGF-β1-mediated membrane type 1-matrix metalloproteinase expression

(2010) S Dangi-Garimella et al.   ONCOGENE

Mir-30 reduction maintains self-renewal and inhibits apoptosis in breast tumor-initiating cells

(2010) F Yu et al.   ONCOGENE

MicroRNA miR-93 promotes tumor growth and angiogenesis by targeting integrin-β8

(2010) L Fang et al.   ONCOGENE

microRNA 17/20 inhibits cellular invasion and tumor metastasis in breast cancer by heterotypic signaling

(2010) Z. Yu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Granulocyte-colony stimulating factor promotes lung metastasis through mobilization of Ly6G+Ly6C+ granulocytes

(2010) M. Kowanetz et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Mammary Gland ECM Remodeling, Stiffness, and Mechanosignaling in Normal Development and Tumor Progression

(2010) P. Schedin et al.   Cold Spring Harbor Perspectives in Biology

MicroRNA 29b functions in acute myeloid leukemia

(2009) R. Garzon et al.   BLOOD

CD4+ T Cells Regulate Pulmonary Metastasis of Mammary Carcinomas by Enhancing Protumor Properties of Macrophages

(2009) David G. DeNardo et al.   CANCER CELL

Hypoxia-Induced Lysyl Oxidase Is a Critical Mediator of Bone Marrow Cell Recruitment to Form the Premetastatic Niche

(2009) Janine T. Erler et al.   CANCER CELL

Matrix Crosslinking Forces Tumor Progression by Enhancing Integrin Signaling

(2009) Kandice R. Levental et al.   CELL

RETRACTED: A Pleiotropically Acting MicroRNA, miR-31, Inhibits Breast Cancer Metastasis

(2009) Scott Valastyan et al.   CELL

MicroRNA-17-3p is a prostate tumor suppressor in vitro and in vivo, and is decreased in high grade prostate tumors analyzed by laser capture microdissection

(2009) Xueping Zhang et al.   CLINICAL & EXPERIMENTAL METASTASIS

Targeting of Integrin β1 and Kinesin 2α by MicroRNA 183

(2009) Guorong Li et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Biological Functions of miR-29b Contribute to Positive Regulation of Osteoblast Differentiation

(2009) Zhaoyong Li et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

GATA3 in development and cancer differentiation: Cells GATA have it!

(2009) Jonathan Chou et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Pten in stromal fibroblasts suppresses mammary epithelial tumours

(2009) Anthony J. Trimboli et al.   NATURE

MicroRNA MiR-17 retards tissue growth and represses fibronectin expression

(2009) Sze Wan Shan et al.   NATURE CELL BIOLOGY

Regulation of HIF-1α and VEGF by miR-20b Tunes Tumor Cells to Adapt to the Alteration of Oxygen Concentration

(2009) Zhang Lei et al.   PLoS One

Dicer-regulated microRNAs 222 and 339 promote resistance of cancer cells to cytotoxic T-lymphocytes by down-regulation of ICAM-1

(2009) R. Ueda et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

GATA-3 Links Tumor Differentiation and Dissemination in a Luminal Breast Cancer Model

(2008) Hosein Kouros-Mehr et al.   CANCER CELL

NF-κB–YY1–miR-29 Regulatory Circuitry in Skeletal Myogenesis and Rhabdomyosarcoma

(2008) Huating Wang et al.   CANCER CELL

miR-126 Regulates Angiogenic Signaling and Vascular Integrity

(2008) Jason E. Fish et al.   DEVELOPMENTAL CELL

MicroRNA-183 regulates Ezrin expression in lung cancer cells

(2008) Guofu Wang et al.   FEBS LETTERS

Endogenous human microRNAs that suppress breast cancer metastasis

(2008) Sohail F. Tavazoie et al.   NATURE

The miR-15a–miR-16-1 cluster controls prostate cancer by targeting multiple oncogenic activities

(2008) Désirée Bonci et al.   NATURE MEDICINE

MicroRNA 29c is down-regulated in nasopharyngeal carcinomas, up-regulating mRNAs encoding extracellular matrix proteins

(2008) S. Sengupta et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Dysregulation of microRNAs after myocardial infarction reveals a role of miR-29 in cardiac fibrosis

(2008) E. van Rooij et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA