Activities of multiple cancer-related pathways are associated withBRAFmutation and predict the resistance to BRAF/MEK inhibitors in melanoma cells

IFN-  Induces Transcription of Hypoxia-Inducible Factor-1  to Inhibit Proliferation of Human Endothelial Cells

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Epigenetic genes regulated by the BRAFV600E signaling are associated with alterations in the methylation and expression of tumor suppressor genes and patient survival in melanoma

(2012) Dingxie Liu et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Molecular Pathways: Interferon/Stat1 Pathway: Role in the Tumor Resistance to Genotoxic Stress and Aggressive Growth

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The Dual Role of Tumor Necrosis Factor (TNF) in Cancer Biology

(2012) L. Bertazza et al.   CURRENT MEDICINAL CHEMISTRY

Hypoxia-inducible factors as key regulators of tumor inflammation

(2012) Soulafa Mamlouk et al.   INTERNATIONAL JOURNAL OF CANCER

Mechanism of TNF-α autocrine effects in hypoxic cardiomyocytes: Initiated by hypoxia inducible factor 1α, presented by exosomes

(2012) Xian Yu et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

The Cancer Cell Line Encyclopedia enables predictive modelling of anticancer drug sensitivity

(2012) Jordi Barretina et al.   NATURE

Vemurafenib: the first drug approved for BRAF-mutant cancer

(2012) Gideon Bollag et al.   NATURE REVIEWS DRUG DISCOVERY

MAP kinase signaling and inhibition in melanoma

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Hypoxia promotes ligand-independent EGF receptor signaling via hypoxia-inducible factor-mediated upregulation of caveolin-1

(2012) Y. Wang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Inhibiting EGF Receptor or SRC Family Kinase Signaling Overcomes BRAF Inhibitor Resistance in Melanoma

(2012) Maria R. Girotti et al.   Cancer Discovery

Genotype-Selective Combination Therapies for Melanoma Identified by High-Throughput Drug Screening

(2012) Matthew A. Held et al.   Cancer Discovery

LIBSVM

(2012) Chih-Chung Chang et al.   ACM Transactions on Intelligent Systems and Technology

Use of Gene Expression and Pathway Signatures to Characterize the Complexity of Human Melanoma

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Acquired and intrinsic BRAF inhibitor resistance in BRAF V600E mutant melanoma

(2011) Inna V. Fedorenko et al.   BIOCHEMICAL PHARMACOLOGY

β-Catenin Signaling Controls Metastasis in Braf-Activated Pten-Deficient Melanomas

(2011) William E. Damsky et al.   CANCER CELL

RANK Is Expressed in Metastatic Melanoma and Highly Upregulated on Melanoma-Initiating Cells

(2011) Verena Kupas et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

STAT3 SIGNALING: Anticancer Strategies and Challenges

(2011) P. A. Johnston et al.   MOLECULAR INTERVENTIONS

Taming the dragon: genomic biomarkers to individualize the treatment of cancer

(2011) Ian J Majewski et al.   NATURE MEDICINE

Improved Survival with Vemurafenib in Melanoma with BRAF V600E Mutation

(2011) Paul B. Chapman et al.   NEW ENGLAND JOURNAL OF MEDICINE

Transcriptional Pathway Signatures Predict MEK Addiction and Response to Selumetinib (AZD6244)

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Clinical Correlates of NRAS and BRAF Mutations in Primary Human Melanoma

(2010) J. A. Ellerhorst et al.   CLINICAL CANCER RESEARCH

Predicting and preventing melanoma invasiveness: advances in clarifying E2F1 function

(2010) Brigitte M Pützer et al.   Expert Review of Anticancer Therapy

Analysis of the genome to personalize therapy for melanoma

(2010) M A Davies et al.   ONCOGENE

A pathway-based classification of human breast cancer

(2010) M. L. Gatza et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Dangerous liaisons: STAT3 and NF-κB collaboration and crosstalk in cancer

(2009) Sergei I. Grivennikov et al.   CYTOKINE & GROWTH FACTOR REVIEWS

BrafV600E cooperates with Pten loss to induce metastatic melanoma

(2009) David Dankort et al.   NATURE GENETICS

Mechanisms of c-Myc Degradation by Nickel Compounds and Hypoxia

(2009) Qin Li et al.   PLoS One

Deoxyribonucleic Acid Profiling Analysis of 40 Human Thyroid Cancer Cell Lines Reveals Cross-Contamination Resulting in Cell Line Redundancy and Misidentification

(2008) Rebecca E. Schweppe et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Oncogenes and Cancer

(2008) Carlo M. Croce   NEW ENGLAND JOURNAL OF MEDICINE

C-MYC overexpression is required for continuous suppression of oncogene-induced senescence in melanoma cells

(2008) D Zhuang et al.   ONCOGENE

Transactivation of EGF receptor and ErbB2 protects intestinal epithelial cells from TNF-induced apoptosis

(2008) T. Yamaoka et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA