Differential regulation of FBXW7 isoforms by various stress stimuli

Fbw7 Repression by Hes5 Creates a Feedback Loop That Modulates Notch-Mediated Intestinal and Neural Stem Cell Fate Decisions

(2013) Rocio Sancho et al.   PLOS BIOLOGY

p53 negatively regulates Aurora A via both transcriptional and posttranslational regulation

(2012) Chun-Chi Wu et al.   CELL CYCLE

Tumor suppressor functions of FBW7 in cancer development and progression

(2012) Zhiwei Wang et al.   FEBS LETTERS

Fbxw7β resides in the endoplasmic reticulum membrane and protects cells from oxidative stress

(2011) Akinobu Matsumoto et al.   CANCER SCIENCE

MiRNA-27a controls FBW7/hCDC4-dependent cyclin E degradation and cell cycle progression

(2011) Mikael Lerner et al.   CELL CYCLE

Emerging roles of the FBW7 tumour suppressor in stem cell differentiation

(2011) Zhiwei Wang et al.   EMBO REPORTS

SCFFBW7 regulates cellular apoptosis by targeting MCL1 for ubiquitylation and destruction

(2011) Hiroyuki Inuzuka et al.   NATURE

Sensitivity to antitubulin chemotherapeutics is regulated by MCL1 and FBW7

(2011) Ingrid E. Wertz et al.   NATURE

The tumour suppressor C/EBPδ inhibits FBXW7 expression and promotes mammary tumour metastasis

(2010) Kuppusamy Balamurugan et al.   EMBO JOURNAL

MicroRNA-223 Regulates Cyclin E Activity by Modulating Expression of F-box and WD-40 Domain Protein 7

(2010) Yanfei Xu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Presenilin modulates EGFR signaling and cell transformation by regulating the ubiquitin ligase Fbw7

(2010) V Rocher-Ros et al.   ONCOGENE

Visualizing Spatiotemporal Dynamics of Multicellular Cell-Cycle Progression

(2008) Asako Sakaue-Sawano et al.   CELL

Transcriptional repression of c-Jun's E3 ubiquitin ligases contributes to c-Jun induction by UV

(2008) Shira Anzi et al.   CELLULAR SIGNALLING

Isoform- and cell cycle–dependent substrate degradation by the Fbw7 ubiquitin ligase

(2008) Jonathan E. Grim et al.   JOURNAL OF CELL BIOLOGY

Fbw7 regulates the activity of endoreduplication mediators and the p53 pathway to prevent drug-induced polyploidy

(2008) S Finkin et al.   ONCOGENE