Wip1 sensitizes p53-negative tumors to apoptosis by regulating the Bax/Bcl-xLratio
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Title
Wip1 sensitizes p53-negative tumors to apoptosis by regulating the Bax/Bcl-xLratio
Authors
Keywords
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Journal
CELL CYCLE
Volume 11, Issue 10, Pages 1883-1887
Publisher
Informa UK Limited
Online
2012-05-16
DOI
10.4161/cc.19901
References
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Related references
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- (2011) A. R. Goloudina et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- The p53 Pathway as a Target in Cancer Therapeutics: Obstacles and Promise
- (2011) A. Mandinova et al. Science Translational Medicine
- Dephosphorylation of γ-H2AX by WIP1: An important homeostatic regulatory event in DNA repair and cell cycle control
- (2010) Sung-Hwan Moon et al. CELL CYCLE
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- p53 and NF-κB: different strategies for responding to stress lead to a functional antagonism
- (2010) Prashanth Ak et al. FASEB JOURNAL
- Modes of p53 Regulation
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- Targeting Protein Serine/Threonine Phosphatases for Drug Development
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- WIP1 phosphatase is a negative regulator of NF-κB signalling
- (2009) Joanne Chew et al. NATURE CELL BIOLOGY
- Chk1 deficiency in the mouse small intestine results in p53-independent crypt death and subsequent intestinal compensation
- (2009) K R Greenow et al. ONCOGENE
- The type 2C phosphatase Wip1: An oncogenic regulator of tumor suppressor and DNA damage response pathways
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- Dual Regulation of Cdc25A by Chk1 and p53-ATF3 in DNA Replication Checkpoint Control
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- (2008) Matteo Rossi et al. NUCLEIC ACIDS RESEARCH
- Runx2-mediated activation of the Bax gene increases osteosarcoma cell sensitivity to apoptosis
- (2008) R A Eliseev et al. ONCOGENE
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