Wip1 promotes RUNX2-dependent apoptosis in p53-negative tumors and protects normal tissues during treatment with anticancer agents

Targeting p53 for Novel Anticancer Therapy

(2014) Zhen Wang et al.   Translational Oncology

Bcl-xL Retrotranslocates Bax from the Mitochondria into the Cytosol

(2011) Frank Edlich et al.   CELL

The apoptotic response in HCT116 BAX-/- cancer cells becomes rapidly saturated with increasing expression of a GFP-BAX fusion protein

(2010) Sheila J Semaan et al.   BMC CANCER

Runx2 in human breast carcinoma: its potential roles in cancer progression

(2010) Yoshiaki Onodera et al.   CANCER SCIENCE

Tiling Path Genomic Profiling of Grade 3 Invasive Ductal Breast Cancers

(2009) R. Natrajan et al.   CLINICAL CANCER RESEARCH

PPM1D Is a Potential Therapeutic Target in Ovarian Clear Cell Carcinomas

(2009) D. S.P. Tan et al.   CLINICAL CANCER RESEARCH

p38MAPK Controls Expression of Multiple Cell Cycle Inhibitors and Islet Proliferation with Advancing Age

(2009) Esther Sook Miin Wong et al.   DEVELOPMENTAL CELL

FGF2-activated ERK Mitogen-activated Protein Kinase Enhances Runx2 Acetylation and Stabilization

(2009) Ok-Jin Park et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Identification and Functional Characterization of ERK/MAPK Phosphorylation Sites in the Runx2 Transcription Factor

(2009) Chunxi Ge et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Post-translational Regulation of Runx2 in Bone and Cartilage

(2009) J.H. Jonason et al.   JOURNAL OF DENTAL RESEARCH

Chk1 deficiency in the mouse small intestine results in p53-independent crypt death and subsequent intestinal compensation

(2009) K R Greenow et al.   ONCOGENE

Posttranslational Modification of p53: Cooperative Integrators of Function

(2009) D. W. Meek et al.   Cold Spring Harbor Perspectives in Biology

The type 2C phosphatase Wip1: An oncogenic regulator of tumor suppressor and DNA damage response pathways

(2008) Xiongbin Lu et al.   CANCER AND METASTASIS REVIEWS

Dual Regulation of Cdc25A by Chk1 and p53-ATF3 in DNA Replication Checkpoint Control

(2008) Anastasia R. Demidova et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Runx2-mediated activation of the Bax gene increases osteosarcoma cell sensitivity to apoptosis

(2008) R A Eliseev et al.   ONCOGENE

A Small Molecular Scaffold for Selective Inhibition of Wip1 Phosphatase

(2007) Jeong Bang et al.   ChemMedChem