Identifying USPs regulating immune signals in Drosophila: USP2 deubiquitinates Imd and promotes its degradation by interacting with the proteasome

Negative regulation of NF-κB signaling in T lymphocytes by the ubiquitin-specific protease USP34

(2013) Konstantinos Poalas et al.   Cell Communication and Signaling

Regulation of NF-κB by ubiquitination

(2013) Jueqi Chen et al.   CURRENT OPINION IN IMMUNOLOGY

The Drosophila ubiquitin-specific protease Puffyeye regulates dMyc-mediated growth

(2013) L. Li et al.   DEVELOPMENT

fat facetsinduces polyubiquitination of Imd and inhibits the innate immune response inDrosophila

(2013) Yoshimasa Yagi et al.   GENES TO CELLS

Proteomic characterization ofPseudomonas aeruginosaPAO1 inner membrane

(2013) Maria G. Casabona et al.   PROTEOMICS

Ubiquitylation in immune disorders and cancer: from molecular mechanisms to therapeutic implications

(2012) Simone Fulda et al.   EMBO Molecular Medicine

Regulation of NF-κB by deubiquitinases

(2012) Edward W. Harhaj et al.   IMMUNOLOGICAL REVIEWS

Cellular functions of the DUBs

(2012) M. J. Clague et al.   JOURNAL OF CELL SCIENCE

The Proteomics Identifications (PRIDE) database and associated tools: status in 2013

(2012) Juan Antonio Vizcaíno et al.   NUCLEIC ACIDS RESEARCH

The ubiquitin-specific protease USP2a prevents endocytosis-mediated EGFR degradation

(2012) Z Liu et al.   ONCOGENE

Systematic Analysis of the Physiological Importance of Deubiquitinating Enzymes

(2012) Wei-Ling Tsou et al.   PLoS One

USP2a Activation of MYC in Prostate Cancer

(2012) William G. Nelson et al.   Cancer Discovery

A Targeted In Vivo RNAi Screen Reveals Deubiquitinases as New Regulators of Notch Signaling

(2012) Junzheng Zhang et al.   G3-Genes Genomes Genetics

USP2a positively regulates TCR-induced NF-κB activation by bridging MALT1-TRAF6

(2012) Yi Li et al.   Protein & Cell

De-ubiquitinating protease USP2a targets RIP1 and TRAF2 to mediate cell death by TNF

(2011) A-L Mahul-Mellier et al.   CELL DEATH AND DIFFERENTIATION

Control of AIF-mediated cell death by antagonistic functions of CHIP ubiquitin E3 ligase and USP2 deubiquitinating enzyme

(2011) K H Oh et al.   CELL DEATH AND DIFFERENTIATION

An RNAi screen identifies USP2 as a factor required for TNF-α-induced NF-κB signaling

(2011) Marie Metzig et al.   INTERNATIONAL JOURNAL OF CANCER

Ubiquitin-specific Cysteine Protease 2a (USP2a) Regulates the Stability of Aurora-A

(2011) Yan Shi et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Yeast Deubiquitinase Ubp3 Interacts with the 26 S Proteasome to Facilitate Rad4 Degradation

(2010) Peng Mao et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Caspase-Mediated Cleavage, IAP Binding, and Ubiquitination: Linking Three Mechanisms Crucial for Drosophila NF-κB Signaling

(2010) Nicholas Paquette et al.   MOLECULAR CELL

Tracing the history of the ubiquitin proteolytic system: The pioneering article

(2009) Aaron Ciechanover   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

The Drosophila Ubiquitin-Specific Protease dUSP36/Scny Targets IMD to Prevent Constitutive Immune Signaling

(2009) Dominique Thevenon et al.   Cell Host & Microbe

Suppression of Cancer Cell Growth by Promoting Cyclin D1 Degradation

(2009) Jing Shan et al.   MOLECULAR CELL

MdmX is a substrate for the deubiquitinating enzyme USP2a

(2009) N Allende-Vega et al.   ONCOGENE

Down-regulation of the De-ubiquitinating Enzyme Ubiquitin-specific Protease 2 Contributes to Tumor Necrosis Factor-α-induced Hepatocyte Survival

(2008) Florian Haimerl et al.   JOURNAL OF BIOLOGICAL CHEMISTRY